This article addresses the challenges and reflections of a junior anthropologist while developing research on the delicate topic of reproductive health and infertility in Maputo, Mozambique. Based on participant observation notes, entries in fieldwork diaries, and interviews, and assuming the character of a reflexive ethnographic account, the article concerns personal and research challenges and opportunities experienced during the preparation and development of a research project and a PhD thesis. While reflecting more broadly on processes of knowledge production, history and colonial relations, and on the writing of a scientific account, it provides insights into the pragmatics of research in medical anthropology by detailing the everyday life of doing ethnography, including networking, bureaucratic processes, boredom, the exploration of new fieldwork landscapes, and positionality dilemmas.