Chemical Standards and HPTLC Finger Print Profiles of a Siddha Polyherbal Formulation - Kadukkai Legiyam

To study physico-chemical, phytochemical and high performance thin layer chromatography of a Siddha drug “Kadukkai Legiyam” (KL). The prepared Kadukkai Legiyam (KL) was prepared as per the standard operating procedures mentioned in literature. Then the drug was subjected to physicochemical parameters, phytochemical screening, thin layer chromatographic photo documentation (TLC), high performance thin layer chromatographic (HPTLC) finger print profile of hexane, chloroform, ethanol and hydro alcohol (1:1) extracts. Different extracts of the drug showed distinct TLC and HPTLC finger print patterns which will be unique to this drug. This study giving information about physiochemical and phytochemical analysis and HPTLC fingerprint profile of different extracts, the integration spectrum which will useful in standardizing the raw drugs and future comparison studies.

Relationship between finger print patterns with blood group and genotype among basic medical science, students of Bayero University, Kano

Fingerprint patterns and the blood genotypes of individuals are chiefly determined by genetic factors during in-utero development. Evaluating genotypes requires expertise and facilities which could relatively be difficult to obtain and operate in some setting. The aim of the current study was to determine the correlation between hand finger print patterns and the common blood typing phenotype (genotype and blood group) among agroup of consenting adult population in Nigeria. Four hundred students (217 males and 183 females) of the Faculty of Basic Medical Sciences in Bayero University Kano had their total hand fingerprints captured using a scanner / computer set up. Data regarding common blood phenotypes was also determined for all participants from the blood phenotype information on their University identification cards. The mean age of theparticipants was 21.86±3.37 years. Loop finger prints patternwas the most common identified in the participants (58.4%), followed by whorls (27.9%), and then the least was arches (13.7%). There was a significant association between the finger print patternon the left thumb (p=0.012) as well as right thumb (p=0.013) withblood groups, while the print in the right index (p=0.042) and left little finger (p= 0.024) were associated with genotypes in the participants respectively. There was a relationship between the finger prints patterns the thumb, index finger and little finger with the common blood typing phenotypes. Thus, finger print patterns on the right index and left little fingercorrelates with blood genotypes.

FINGER RIDGE PATTERNS IN PSORIASIS PATIENTS

Psoriasis is a chronic inflammatory disorder of the skin. In India the prevalence of psoriasis varies from 0.44 to 2.8%, it is twice more common in males compared to females. Beyond the physical dimensions of disease, psoriasis has an extensive emotional and psychosocial effects on patients. Dermatoglyphics is the study of epidermal ridges and grooves on palm and sole which is formed during the third or fourth month of foetal life which remain unchanged till death. The present study is an attempt to correlate the differences in fingertip patterns of psoriasis patients with controls. In this study 54 male patients and 100 controls are included from a tertiary care teaching institution in North Kerala. There were 46.12% whorls, 48.31% ulnar loops, 1.66% radial loops and 3.91% arches among the patients. Among the controls it was 42.8%, 51.2%, 2.4% and 3.6% respectively. When the fingers are individually considered thumb and second and fourth fingers have more whorls in both cases and controls. Of these the increase of whorls on the fourth finger (ring finger) on right side among patients is statistically significant. Pattern intensity index, Dankmeijer’s index and Furuhata’s index are reported. The findings of the study are suggestive of a possible trend and an association of finger print patterns with patients suffering from psoriasis.

Comparative study of dermatoglyphic patterns in identical twins

Background and aims: Dermatoglyphics has been studied extensively in chromosomal disorders and also in various diseases. Identical twins cannot be distinguished based on DNA. It is claimed that identical twins can be distinguished based on their finger prints, retina, and thermogram and iris patterns. It will be really interesting to know whether the identical twins have same dermatoglyphic patterns or not. Materials and Methods: 24 pairs of identical twins were examined for quantitative and qualitative similarities of finger print patterns; patterns on the palm, ‘atd’angle, ‘a-b’ridge count and palmar creases. Finger prints were evaluated for loop, arch, whorl and the data was recorded. Paired sample correlation test was applied to analyse ‘a-b’ridge count and ‘atd’ angle. Results: We have found that on comparison of finger tip patterns there are differences of about 33.33%. ‘a-b’ridge count in cases studied showed mean range from 38.23 to 38.37 on right and left hands respectively. This indicates there is close similarity in the ‘a-b’ridge count of identical twins, ‘atd’ angle showed close similarity in mean ranging from 46.23 to 46.10 on right and left hand respectively. Conclusion: Finger tip patterns is superior parameter to differentiate Identical twins compared to ‘a-b’ridge count and ‘atd’ angle.