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2021 ◽  
Vol 10 (4) ◽  
pp. 89-94
Author(s):  
M. V. Mikhalkina ◽  
K. P. Mikhalkin

The article is dedicated to the outstanding Russian histologist Professor Anton Vitalievich Nemilov, who, being a student of St. Petersburg Imperial University, was one of the first students of Alexander Stanislavovich Dogel, the world-famous Russian scientist, the founder of neurohistology. Having so far shown a bright talent of a researcher and experimenter in his student years, Anton Vitalievich was invited to prepare for a professorship at the university and over and above met expectations based on him. He significantly contributed to the development of neurohistology, histophysiology, including histophysiology of the reproductive system. Anton Vitalievich did a lot for development of endocrinology, which he studied in a general biological but not in a purely medical aspect; this was new and valuable for that period. Finally, he made his contribution to the development of cell theory. A talented teacher, an excellent lecturer, an author of a number of brilliant textbooks, a consummate popularizer of science, an active public figure – Anton Vitalievich demonstrated so many diverse talents during his life, which was not really long, that their combination in one person seems simply unbelievable. His life was in full swing, he was full of creative plans, but the Great Patriotic War prevented their implementation. It started when Anton Vitalievich was 62 years old. Professor A.V. Nemilov wanted to continue research at his native Leningrad University, refused to be evacuated, and remained in the besieged city. With his peculiar enthusiasm, Anton Vitalievich joined defense work, angrily denounced fascism in his articles and radio speeches. However, hunger and cold of the blockade undermined his strength, and he died of exhaustion on February 2, 1942. He was under 63 years old. The article dedicated to Anton Vitalievich Nemilov presents milestones of his life and work, his contribution to science, his professional and personal traits. The paper also highlights his participation in the fight against fascism and tragic death during the blockade of Leningrad.


Religions ◽  
2021 ◽  
Vol 12 (12) ◽  
pp. 1099
Author(s):  
Sam Challis ◽  
Andrew Skinner

With earlier origins and a rebirth in the late 1990s, the New Animisms and the precipitate ‘ontological turn’ have now been in full swing since the mid-2000s. They make a valuable contribution to the interpretation of the rock arts of numerous societies, particularly in their finding that in animist societies, there is little distinction between nature and culture, religious belief and practicality, the sacred and the profane. In the process, a problem of perspective arises: the perspectives of such societies, and the analogical sources that illuminate them, diverge in more foundational terms from Western perspectives than is often accounted for. This is why archaeologists of religion need to be anthropologists of the wider world, to recognise where animistic and shamanistic ontologies are represented, and perhaps where there is reason to look closely at how religious systems are used to imply Cartesian separations of nature and culture, religious and mundane, human/person and animal/non-person, and where these dichotomies may obscure other forms of being-in-the-world. Inspired by Bird-David, Descola, Hallowell, Ingold, Vieiros de Castro, and Willerslev, and acting through the lens of navigation in a populated, enculturated, and multinatural world, this contribution locates southern African shamanic expressions of rock art within broader contexts of shamanisms that are animist.


2021 ◽  
Vol 9 (12) ◽  
pp. 232596712110608
Author(s):  
Lindsay S. Flynn ◽  
George J. Richard ◽  
Heather K. Vincent ◽  
Michelle Bruner ◽  
Cong Chen ◽  
...  

Background: Bat swing and grip type may contribute to hook of hamate fractures in baseball players. Purpose: To compare the effects of swing type and batting grip on the pressure and rate of pressure development over the hook of hamate in collegiate baseball players. Study Design: Descriptive laboratory study. Level of evidence, 3. Methods: This was an experimental quasi-randomized study of bat grip and swing differences in National Collegiate Athletic Association Division I baseball players (N = 14; age, 19.6 ± 1.1 years [mean ± SD]). All participants performed swings under 6 combinations: 3 grip types (all fingers on the bat shaft [AO], one finger off the bat shaft [OF], and choked up [CU]) and 2 swing types (full swing and check swing). Peak pressure and rate of pressure generation over the area of the hamate were assessed using a pressure sensor fitted to the palm of the bare hand over the area of the hamate. Wrist angular velocities and excursions of radial ulnar deviation were obtained using 3-dimensional motion analysis. Results: The OF–check swing combination produced the highest peak pressure over the hamate (3.72 ± 2.64 kg/cm2) versus the AO–full swing (1.36 ± 0.73 kg/cm2), OF–full swing (1.68 ± 1.17 kg/cm2), and CU–full swing (1.18 ± 0.96 kg/cm2; P < .05 for all). There was a significant effect of condition on rate of pressure development across the 6 conditions ( P = .023). Maximal wrist angular velocities were 44% lower in all check swing conditions than corresponding full swing conditions ( P < .0001). The time to achieve the maximal wrist angular velocity was longest with the AO–full swing and shortest with the CU–check swing (100.1% vs 7.9% of swing cycle; P = .014). Conclusion: The OF–check swing condition produced the highest total pressure reading on the hook of hamate. Check swing conditions also had the steepest rate of pressure development as compared with the full swing conditions. Clinical Relevance: Batters who frequently check their swings and use an OF or AO grip may benefit from bat modifications or grip adjustment to reduce stresses over the hamate. Athletic trainers and team physicians should be aware of these factors to counsel players in the context of previous or ongoing hand injury.


2021 ◽  
pp. 1-25
Author(s):  
Jie Xu ◽  
Wenhui Zhou ◽  
Suzhi Zhang ◽  
Jinhua Fu

With the vigorous development of blockchain technology represented by bitcoin, blockchain technology has gradually entered the stage of blockchain 3.0 characterized by “programmable society”. And the application of blockchain technology in all walks of life has achieved actual results. Blockchain technology has typical characteristics of decentralization, Tamper-resistant data, information openness and transparency, and natural fit with the application requirements in the field of certificate tracing, which makes the development of the applications of blockchain deposit and traceability in full swing. First, this paper describes the concept, application process, key technology of blockchain deposit and traceability, the three application architectures of blockchain deposit and traceability, and the overall architecture of its system. Then, it introduces the application of scenarios and the blockchain deposit and traceability in various fields. Next, it discusses the issues existing in the development of the application of blockchain deposit and traceability. Finally, the paper also expresses the best wishes for the future of its application.


2021 ◽  
Vol 9 (47) ◽  
pp. 11593-11607
Author(s):  
Akhilesh Kumar Dixit

Priority sector lending, non-priority sector lending, corporate debt restructuring and accumulation of non- performing assets have now become an interesting topic of discussion and debate. Evolution of priority sector credit since social control of banks back in 1967 has a chequered history till emergence of micro finance as a tool of poverty alleviation. Various committees formed by RBI and the Government of India have reviewed progress of priority sector lending and recommended measures for revamping the structural and operational measures related to social banking. On the other side, non-priority sector NPAs and corporate debt restructuring seems to be alarming nowadays. Till the year 2011 the situation was different, but after 2011 with the implication of BASEL II, banks are bound to show their stressed assets and restructuring measures are in full swing. In 2015 the corporate debt restructuring was highest in last 10 years. With the introduction of financial sector reforms and adoption of prudential accounting norms following BASEL convention, the banks have been passing through tremendous crisis with phenomenal growth of nonperforming assets. This paper analyses the growth of priority sector non-performing assets, non-priority sector non-performing assets and its contribution towards building up total non-performing assets and investigates the relationship of non-performing assets with some economic parameters. It also analyses the association of corporate debt restructuring with non-performing assets and tries to find out relationship of the above two. A strong correlation is found between corporate debt restructuring and NPAs. A negative association is found between NPAs and GDP growth.


2021 ◽  
Vol 4 (3) ◽  
pp. 01-03
Author(s):  
Shahidul Islam ◽  
Farhana Hoque ◽  
Moushume Chowdhury

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has induced a sense of panic around the world as the disease is highly contagious and has been spreading in full swing. This study was aimed to investigate SARS-CoV-2 associated epidemiology and clinical outcomes in Bangladesh in order to understand the future course of COVID-19 pandemic and develop prevention approaches. A cross-sectional retrospective interview based study was conducted on RT-PCR confirmed COVID-19 patients admitted in Chattagram Maa O Shishu General Hospital Chittagong, Bangladesh and who recovered four weeks prior to the interview date. Of the total 500 patients, 7% patient are asymptomatic where as for the symptoms associated with COVID-19 fever (85%) and cough (70%) were the most prominent among cases. Our study has revealed that among the age groups, the 40-70 showed the highest infection rate (74.7%) and in terms of gender, the prevalence of Covid-19 infection in males (65%) was 2 times more than that in females (35%). Diabetes was found about (40%) and Hypertension was found (42%), so diabetic and hypertesive patient are more affected. The most used drug is Enoxaparin sodium, Methylprednisolone Na Succinate, Montelucast, fexofenadinb, Doxycyclline, Doxofylline, zinc, vitamin-C, D and about 60% patient need oxygen supply. The most complication after recovery is weak -fatigue, cough & breathing problem.


Vaccines ◽  
2021 ◽  
Vol 9 (10) ◽  
pp. 1067
Author(s):  
Irfan A. Rather ◽  
Sy-Bing Choi ◽  
Majid Rasool Kamli ◽  
Khalid Rehman Hakeem ◽  
Jamal S. M. Sabir ◽  
...  

In response to the ongoing COVID-19 pandemic, the global effort to develop high efficacy countermeasures to control the infection are being conducted at full swing. While the efficacy of vaccines and coronavirus drugs are being tested, the microbiome approach represents an alternative pathophysiology-based approach to prevent the severity of the infection. In the current study, we evaluated the action of a novel probiotic Lactobacillus plantarum Probio-88 against SARS-COV-2 replication and immune regulation using an in vitro and in silico study. The results showed that extract from this strain (P88-CFS) significantly inhibited the replication of SARS-COV-2 and the production of reactive oxygen species (ROS) levels. Furthermore, compared with infected cells, P88-CFS treated cells showed a significant reduction in inflammatory markers such as IFN-α, IFN-β, and IL-6. Using an in silico molecular docking approach, it was postulated that the antiviral activity of L. plantarum Probio-88 was derived from plantaricin E (PlnE) and F (PlnF). The high binding affinity and formation of hydrogen bonding indicated that the association of PlnE and PlnF on SARS-COV-2 helicase might serve as a blocker by preventing the binding of ss-RNA during the replication of the virus. In conclusion, our study substantiated that P88-CFS could be used as an integrative therapeutic approach along with vaccine to contain the spread of the highly infectious pathogen and possibly its variants.


Author(s):  
Shahbaz Hussain ◽  
Mehedi Hasan ◽  
Gazal Agrawal ◽  
Mohd Hasan

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