Scalable approach towards specific and ultrasensitive cation sensing in harsh environmental conditions by engineering the analyte-transducer interface

Affordable and high-performing sensing platforms are becoming increasingly critical for sustainable environmental monitoring and medical diagnostics. Such miniaturized and point-of-care sensing platforms need to overcome the fundamental tradeoff between ultrahigh...

Falsely low arterial blood pressure due to pressure transducer damage in three horses

Three horses undergoing general anaesthesia for orthopaedic procedures between August 2018 and January 2019 at Langford Veterinary Equine Services, Bristol University had falsely low arterial blood pressures due to damage of the non-disposable invasive arterial blood pressure transducer interface. The invasive arterial blood pressure transducer interface is not currently a component that is checked during the anaesthetic machine check prior starting a general anaesthetic procedure. Starting treatment for hypotension based on incorrect information due to faulty equipment can have severe negative consequences for the patient, such as extreme hypertension, increased myocardial workload and oxygen demand, and reduced perfusion of splanchnic and muscle tissue due to vasoconstriction. Therefore, we recommend routinely using the square wave test and checking the integrity of the blood pressure transducer interface before starting a general anaesthetic procedure, and when unexpected hypotensive readings are obtained and/or a state of hypotension is not responsive to treatment.

Efficient Digital System Management using IEEE 1451.0 Enabled Control Architecture

The IEEE and National Institute of Standards and Technology have formulated an open universal standard called IEEE 1451 for ‘Smart Transducer Interface’ with digital systems. The objectives of this paper is to propose IEEE 21450 enabled control architectures for efficient management of power system with embedded system parameters as electronic documentation. The control architecture accommodates appropriate number of transducer interface module along with transducer electronic data sheet, which enables active calibration, adaptive tuning and failure proof operation of system management.

S-layer Protein-based Biosensors

The present Feature Paper highlights the application of bacterial surface (S-) layer proteins as versatile components for the fabrication of biosensors. One technologically relevant feature of S‑layer proteins is their ability to self-assemble on many surfaces and interfaces to form a crystalline 2D protein lattice. The S-layer lattice on the surface of a biosensor becomes part of the interface architecture, linking the bioreceptor to the transducer interface, which may cause signal amplification. The S-layer lattice as ultrathin, highly porous structure with functional groups in a well-defined special distribution and orientation and an overall anti-fouling characteristics can significantly raise the limit in terms of variety and ease of bioreceptor immobilization, compactness of bioreceptor molecule arrangement, sensitivity, specificity, and detection limit for many types of biosensors. The present paper discusses and summarizes examples for the successful implementation of S-layer lattices on biosensor surfaces in order to give a comprehensive overview on the application potential of these bioinspired S-layer protein-based biosensors.

Research and Implementation on Networked Smart Sensor Based on IEEE1451 Standard

Firstly, the background and significance of IEEE1451 standard are introduced. Secondly, each protocol, especially the IEEE1451.2 standard of IEEE1451 family standards, is described respectively, including Smart Transducer Interface Module(STIM), Network Capable Application Processor (NCAP) and Transducer Electronic Data Sheet(TEDS). Then, a new design idea and implementation of a kind of networked smart sensor based on the IEEE451.2 is introduced in detail. Finally, the advantages and trends of the smart sensor based on IEEE1451 standard are summarized.