Towards the Possibility of Additive Manufacturing of XNA-Based Devices Using Molecular Engineering Principles

This paper considers a novel approach for integration between molecular engineering of XNA-based structures and additive manufacturing of XNA-based devices based on multiparametric characterization of XNAs by different functional descriptors (such as physical properties of XNA-based materials and precursors of XNA-based molecular devices) and the possibility of thermal or electron-beam processing as a prerequisite of the industrial technical process development for such device implementation. This can be performed in the framework of additive manufacturing by connecting the output of the XNA synthesizer or nucleic acid synthesizer with 3D-printer nozzles in such a way that oligos / AGCTX products are supported into the nozzles separately.

Multiparametric Porcine Oocyte Deformation Characterization by Novel MEMS-Type Cytometer

In this work for the first time MEMS-type deformation microcytometer and a new methodology for the determination of cell deformability is proposed. Novel chip design and methodology allow real-time observation of the cell deformation occurring during compression of oocytes. In addition, software-based analysis of microscopic images allows multiparametric characterization of the investigated cell toward quality assessment of the cell.