Social determinants of health (SDH) are defined as the non-medical yet health-affecting conditions of a person’s life. They include such considerations as working conditions, discrimination, and access to health services. The aim of this study was to explore the SDH impacting those who have survived sex trafficking in Cambodia. This study employed a mixed methods, secondary analysis, focusing on 52 survivors of sex trafficking in the Butterfly Longitudinal Research Project from 2010 through 2019. Participants described myriad social determinants of health, including: gender, age, relationship status (marriage), ethnicity, national identification documentation (statelessness), social class, formal education, vocational training, occupation, and monthly income. The negative impacts of these social determinants of health included: poor access to basic needs of food and clean water, unstable housing, low education rates, worsening physical health, depression, and suicidal ideation, along with long unresolved STI-like symptoms. As these are multidisciplinary issues, the study concludes with recommendations for remedial actions to be taken by multidisciplinary stakeholders, namely government agencies, healthcare professionals, and survivor aftercare service providers.