The upward trend in online graduate degrees, the mobility of graduate students, and the increase in the number of dissertations completed at a distance from universities poses several challenges for faculty who supervise research virtually, students being mentored virtually, and institutions invested in the quality of doctoral education. At the same time, emerging communication technologies present new opportunities for mentoring approaches that build upon those used in traditional on-campus environments. Based on qualitative research with 29 graduates who completed their dissertations at a distance, this chapter presents a framework for the e-mentoring of research and dissertations that encompasses strategies and support at the institutional, mentor, small group, and mentee levels.