FUNCTION AND SAFETY EVALUATION OF 3D TECHNOLOGY TO PREPARE BONE REPAIR BIOMATERIALS

PLGA/HA composite biomaterials are prepared, and 3D printing technology is used to make bone scaffolds that can be implanted in the body. Its performance is tested by in vitro physical and biological methods, and its safety is evaluated by animal experiments. Methods: 3D printing technology was used to print the PLGA/HA composite three-dimensional stent biomaterial, and the tensile strength and bending strength of the stent material were tested with reference to GB/T1040 and GB/T9341 to verify its ability to support the proliferation and differentiation of hMSC. The biological evaluation standard (GB/T16886) evaluates the biocompatibility and biosafety of scaffoldmaterials in vitro and in vivo. Results: The porous 3D scaffold made of PLGA/HA composite material was successfully fabricated; the mechanical tensile strength and flexuralstrength of the composite material were 38 MPa and 42 MPa respectively, which were5.35 times and 5.25 times that of normal human cartilage; in vitro cell test It is proved that the 3D scaffold can support the proliferation and differentiation of hMSC into chondrocytes. The results of the biosafety test show that the scaffold meets the national medical device biological evaluation standards.

SOME MEDICAL-BIOLOGICAL ASPECTS AND ECOLOGICAL BACKGROUND DURING THE USAGE OF POISON CHEMICALS AGAINST THE PATHOGENESIS OF BUXUS COLCHICA

It is proved, that the unique model of Georgian flora, Colchian box-tree (Buxus), is in the phase of ecological catastrophe. The chance of survivalis minimal in the refuges, gorges and mountain slopes. Relict or introductory plants of all Georgian box-tree species should be sprayed with pesticide “Dimelin” and tilled with fungicides. All types of Deltamethryn (Decis) pesticides must be removed from purging scheme, since, according to survey results, abovementioned drug is an ecological threat fot the human health and the fauna complexes.

ПОЛЗУЧЕСТЬПАФ-2 В СПИРТАХ

Is learnt PAF-2 creeping in spirts.Is shown that Metanol’sdiffusion carries as fast as in water, creeping curve in spirits is not different from creeping curve in water.Experiments that took place into spirits solutions and received curves show that if we rise spiritsconcentration it rises polymer’s creeping size and mostly is received S alike curve.

THE METHODOLOGY OF THE FORMATION OF INFORMATION CULTURE OF STUDENTS IN BIOLOGY

The article deals with the dynamic development of information and communication technologies and their impact on the education system, as well as the importance of forming an information culture of students through the use of information technologies in biology lessons. For biological science, which is constantly updated and updated information base, the use of information technologies in the educational process is becoming more rational and acceptable. In particular, the use of a virtual laboratory, an online microscope, multimedia information systems and various animations in biology classes makes the lesson interesting and useful. Thus, with the help of systematic informatization, students can be helped to study in an open education system, toform a system of thinking and independence.This article contributes to the formation of information culture in the process of teaching and training students through information and communication technologies using new information systems in biology lessons and contributes to a more detailed understanding of the problem of Informatization of education.

ЭТИОЛОГИЯ И ОСОБЕННОСТИ ТЕЧЕНИЯ ХБП У ДЕТЕЙ ПРИ ПАТОЛОГИИ МОЧЕВЫДЕЛИТЕЛЬНОЙ СИСТЕМЫ

This article presents data on the development of (chronickidney disease) CKD in children.In particular, with the pathology of the urinary system in children of different age groups.We analyzed the main clinical characteristics and laboratory parameters in children with pathology of the urinary system.The main parameters of the functional state of the kidneys were considered, the glomerular filtration rate (GFR) was calculated using the CKD EPI formula.The chronic pathology of the urinary systemin children was also analyzed.The course of CKD in children with various clinical nosological forms of kidney pathology was studied.

ЕNSURING THЕRЕLIАBILITY ОF TRАNSРОRT

Rоаd sаfеty is bесоming thеnumbеr оnеissuе. Rеliаbility -аbrаnсh оf sсiеnсеthаt studiеs thеgеnеrаl mеаsurеs tоbесоnsidеrеd whеn dеsigning, mаnufасturing аnd ореrаting tесhniсаl systеms, in оrdеr tоеnsurеmахimum еffiсiеnсy in thеir usе.Thесаr is dереndеnt оn thееnvirоnmеnt, оn thерrосеssеs thаt influеnсеthеtriggеring оf its bаsiссhаrасtеristiсs, during ореrаtiоn.Аn ореrаtiоn strаtеgy is аsеt оf rulеs thаt еnsurеthеsресifiеd соntrоl оf thесоrrеsроnding ореrаtiоn рrосеss. Соmmеrсiаl ореrаtiоns gоvеrns thеintеndеd usеоf vеhiсlеs. Аll strаtеgiеs аrесlоsеly rеlаtеd tоit. Thus, thеаutоmоbilеtrаnsроrt systеm hаs thеfеаturеs inhеrеnt in соmрlехtесhniсаl systеms: thерrеsеnсеоf аsinglеgоаl, соntrоllаbility, thеintеrсоnnесtiоn оf еlеmеnts, аhiеrаrсhiсаl struсturе. Thеsystеm оf tесhniсаl ореrаtiоn оf vеhiсlеs is аsеt оf vеhiсlеs, trаffiссоntrоl dеviсеs, drivеrs, rеgulаtiоns аnd nоrms thаt dеtеrminеthеsеlесtiоn аndmаintеnаnсеоf thеmоst аdvаntаgеоus mоdеs оf ореrаtiоn оf vеhiсlеunits, аs wеll аs thеmаintеnаnсеаnd rеstоrаtiоn оf thеlоst реrfоrmаnсеоf vеhiсlеs in thерrосеss оf реrfоrming trаnsроrt wоrk.Thеrеliаbility оf thесаr is thеаbility оf thесаr tореrfоrm thеsресifiеd funсtiоns, kеерing thеvаluеs оf thееstаblishеd реrfоrmаnсеindiсаtоrs within thеlimits соrrеsроnding tоthеsресifiеd mоdеs аnd соnditiоns оf usе, mаintеnаnсе, rераir, stоrаgеаnd trаnsроrtаtiоn.

ОСОБЕННОСТИХРУСТАЛЕНОСНОСТИУЛЫТАУСКОГОРАЙОНА

The Ulytau crystal-bearing region is located in the western part of the Kazakh folded country, distinguished by a significant complexity of the geological structure. The latter is due to the heterogeneity and varying degrees of dislocation of its constituent rocks.In connection with the manifestation of two stages of tectogenesis, two structural stages are distinguished in the folded base of the Ulytau zone.The purpose of this article is to study the features of the crystal content of the region.On the territory of the Ulytau district, 140 vein fields were identified, numbering up to 6,000 quartz veins, of which 1,700 with signs of crystallinity. Of the total number of crystal-bearing veins, 1100 were explored, located within 75 vein fields. Quartz veins, including crystal-bearing ones, are found in almost all rocks, including deposits of the Middle Carboniferous, which determine the upper age limit of the veins in the region.Productive (industrially -crystal-bearing) mineralization is manifested in the contours of the region more locally. Of the 110 identified fields and areas, industrial mineralization is associated with vein formations only 18 objects.