Survey for Transition of Normal Reaction

Transition of reaction is a short-lived unstable molecule in a reaction which is formed in between the reaction when reactants change into products. Whereas, transition state is just the state before formation of new molecule (involves breaking of bonds of reactants and formation of new ones) Transition of reaction differs from a transition state in that the intermediate has a discrete lifetime (be it a few nanoseconds or many days), whereas a transition state lasts for just one bond vibration cycle. Intermediates may be unstable molecules (in which case they are called reactive intermediates) or highly stable molecules. The difference between them can be better described through the energy profile diagram.

Comprehensive Surgical Management of Chronic Suppurative Osteomyelitis Extending to The Lower Border of Mandible – A Case Report

Osteomyelitis of maxillofacial skeleton is common in developing countries such as India. This case report describes successful surgical treatment of chronic suppurative osteomyelitis {CSO} of the mandible of a 35yr old female. The precipitating factor was thought to be eventful extraction in the {left } posterior body at the inferior border of mandible. Methods: Presurgical course of antibiotics ( Amoxycillin and metronidazole for 7 days and later followed by doxycycline for 1 month).Surgical debridement of the affected bone and reinforcing it with reconstruction plate using AO principles was done . Patient was kept on a high nutrient diet consisting of proteins. Conclusion: The case report demonstrates the typical features of CSO . The combination of the antibiotics therapy and surgical debridement was successful in the treatment of chronic suppurative osteomylitis.

Principles of Nucleophilic Substitution

The work reported in this theoretical paper deals with types of substitution reaction ( sn1 , sn2 , conditions of both reactions , methods of both reactions , diagram of reactions , energy for reactions, types of reactants , products, rate of reactions , steps of reactions, transition state for reaction) and other reactions.

Internet Based Drug Design of New Opioid Analgesics

The development of new drug with its therapeutic potential is one of the most vital process in pharmaceutical industry. Now a day, there is development and importance of computational chemistry including molecular docking and a SAR study which deals with pharmacophore based drug design approach. Also, the methodology linked with modification of the target based drug discovery has been performed by using various computational tools. Thus, the present study deals with the Structural Activity Relationship study and pharmacophore based drug design approaches with the use of internet based tools which are free of cost and compatible with any platform. Here, attempts are made to design OPIORPHIN analogue by pharmacophore study to design more potent or equivalent opioid analgesic using free internet based tools by using Java platform to input structure, calculate its drug likeness, molecular properties and toxicity which are important parameters for structure based rational drug design.

Descartes and the paradigm of Western medicine: an essay

This essay is a contribution to the study of the CartesianDualism (separation of mind-body) and Mechanicism (the body is a machine) that have contributed to the paradigm of Western medicine. These Cartesian ideas of separation and fragmentation of the reality have hampered the implementation of the new paradigm in health care in contemporary society, where the patient is seen in an holistic way: soul-mind-body.

A Review Paper on Specimens Size and Shape Effects on the Concrete Properties

Concrete properties are the most essential and critical physical material property when reinforced concrete structures are planned. Because of the development and in types and nature of material used to enhance the concrete innovation, materials and mix proportions, test measure, mixing strategy, and testing condition have noteworthy impacts on highlights of concrete strength, in light of the fact that the control specimen sizes and shapes might be unique in relation from State to State. Testing of mechanical properties (especially compressive strength and tensile strength) of concrete is one of the most urgent stages of development. To control the nature of the concrete, there are different molds used for pouring concrete samples according to different directions in different countries. Many researchers have realized that the specific shapes and sizes of concrete samples can cause different types in the consequences of compressive strength or tensile strength. The relationship between the compressive strength of the concrete cube and the cylinder is complex. The cylinder and concrete cube samples were compared in the pressure test by studying previous research, including the test methodology, factors affecting the cylinder / cube strength ratio, and the coefficients, equations and components of the conversion factors. Previous attempts to determine experimental transformational relationships and conversion factors have proved that it is disturbing (if not impossible) to predict the relationships between the forces of the cylinder and the cube. Previous research has shown that the ratio of the strength of the cylinder / cube is between 0.65 and 0.90, despite the fact that the ratios outside this range have been found similarly. In light of this review of previous research, the test of the cylinder is not initiated by testing the cube. This study is a review of the sample size and shape effect on concrete properties.

THE ROLE OF FINITE ELEMENT METHOD IN CIVIL ENGINEERING

The finite element method is a numerical method that is used to find solution of mathematical and engineering problems. It basically deals with partial differential equations. It is very complex for civil engineers to study various structures by using analytical method,so they prefer finite element methods over the analytical methods. As it is an approximate solution, therefore several limitationsare associated in the applicationsin civil engineering due to misinterpretationof analyst. Hence, the main aim of the paper is to study the finite element method in details along with the benefits and limitations of using this method in analysis of building components like beams, frames, trusses, slabs etc.

COMPARATIVE PERFORMANCE EVALUATION OF PMB and CRMB WITH PARTIAL REPLACEMENT OF BITUMEN (VG-30) USING MARSHALL MIX DESIGN METHOD-A REVIEW

Waste generated from industries and from various places around us not only contains rubber or plastics but contains lot many harmful pollutants whichare hazardous if disposed continuously in open and leftto degrade in our environment.Our project aims to study properties of different materials which may help in utilising the waste as well as improve the quality of roads and make them efficient, stable, durable and long lasting. Some of the materials that we have studied and considered to be tested in the partial replacement of bitumen are PMB and CRMB.

ORODISPERSIBLE TABLETS:AN OVERVIEW

The oral route is the most widely accepted route.The review deals with overview of orodipersible tablets that includes advantages,disadvantages,properties,methods forits formulation.

HYDROLOGICAL MODELLING FOR KHUSHKHERA-BHIWADI-NEEMRANA INVESTMENT REGION, RAJASTHAN USING SWAT

In India the availability of accurate information of observed runoff is insufficient. However due to water scarcity great emphasis is now placed on preparation of proper watershed management program for conservation and development of land and water management. For the present study, watershed spanning Jaipur and Alwar districts of Rajasthan state of India, with outlet in Khushkhera-Bhiwadi-Neemrana Investment Region (KBNIR) in Rajasthan, under proposed Delhi-Mumbai freight corridor has been selected as the study area for deriving the optimum water use policies. Basic data of the study area were generated with the help of freely available remotely sensed information. Total watershed area is 2995.84 km2, in which 73.27% is agriculture area. The major soil in watershed area is older alluvial soil. On digitization, ArcSWAT created four hundred sixty four hydrological response units by defining unique combinations of the land use, soil cover and slope conditions. By providing all theinputs for model set up, SWAT model was run for the period of thirty five years (1979–2014). Result of actual evapotranspiration and discharge is validated with the output of other modelling exercises of same area. Total average annual surface runoff is calculated to be 94.79 mm out of which highest average monthly runoff is 34.79 mm in the month of July. Total average runoff for the monsoon month is 92.55 mm which is 97.63% of total runoff. Output of this model can be utilized for development of optimum water resource and agricultural management policies of newly development of KBNIR.