INFLUENCE OF THIAMINE ON BLOOD SUGAR LEVELS IN DIABETIC PATIENTS

1940 ◽  
Vol 66 (5) ◽  
pp. 1079 ◽  
Author(s):  
ROBERT E. KAUFMAN
Keyword(s):  
Blood Sugar ◽  
Diabetic Patients ◽  
Sugar Levels

Plasminogen Activation in Diabetes Mellitus: Normalization of Blood Sugar Levels Improves Impaired Enzyme Kinetics In Vitro

1985 ◽  
Vol 54 (02) ◽  
pp. 413-414 ◽  
Author(s):  
Margarethe Geiger ◽  
Bernd R Binder
Keyword(s):  
Plasminogen Activator ◽  
Blood Sugar ◽  
Metabolic Disorders ◽  
Normal Values ◽  
Diabetic Patients ◽  
Type I ◽  
Plasminogen Activation ◽  
Lag Period ◽  
Sugar Levels

SummaryWe have demonstrated previously that fibrin enhanced plasmin formation by the vascular plasminogen activator was significantly impaired, when components isolated from the plasma of three uncontrolled diabetic patients (type I) were used to study plasminogen activation in vitro. In the present study it can be demonstrated that functional properties of the vascular plasminogen activators as well as of the plasminogens from the same three diabetic patients are significantly improved after normalization of blood sugar levels and improvement of HbAlc values. Most pronounced the Km of diabetic vascular plasminogen activator in the presence of fibrin returned to normal values, and for diabetic plasminogen the prolonged lag period until maximal plasmin formation occurred was shortened to almost control values. From these data we conclude that the observed abnormalities of in vitro fibrinolysis are not primarily associated with the diabetic disease, but might be secondary to metabolic disorders caused by diabetes.

scholarly journals Low-Glycemic-Index Sugar in Type 2 Diabetic Patients: A Randomized Controlled Study

2021 ◽  
Author(s):  
Damien Steciuk ◽  
Samia Mahmood Hafez Amir ◽  
Muzzammil Hosenally ◽  
Aroushini Goorapah
Keyword(s):  
Blood Sugar ◽  
Glycemic Index ◽  
Glucose Monitoring ◽  
Controlled Study ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Sugar Levels ◽  
Type 2 Diabetic ◽  
Low Glycemic Index

Abstract Background and Objectives: There is a need to re assess the value of low-GI food and its specific components. The effect of one of them, namely low-glycemic-index sugar, is unclear, as its impact is usually confounded when reported in the literature. This study attempts to breach this gap, shedding light on its effect in type 2 diabetic patients and evaluate if it could be considered as part of a dietary plan.Subjects and Methods: The blood sugar level of twenty (20) type 2 diabetics was monitored using a Continuous Glucose Monitoring system during two phases; firstly, an initial period of 5 days, whereby all the included patients were taking their usual dietary meals. Subjects were then randomized into two groups of equal size before embarking on a second phase; 10 subjects were instructed to eat prepared, portioned and delivered meals, the difference for the second group being that low-GI sugar was used for the preparation. Results: Compared to baseline (day 1), blood sugar dropped by 18% for the group with low-GI sugar and 13% for those who consumed sugar with a normal-GI. The variation in sugar levels was also more contained in the interventional group. A by-product of the study design shows that constant glucose monitoring could raise awareness, and may foster reduction in blood sugar levels. Portioned food was capable of reducing blood sugar levels, with elevated levels of compliance just after start. Conclusions: Even though the ultimate aim is to reduce sugar consumption by diabetic patients, the intake of a low-GI sugar seems to be less harmful than normal sugar. Compared to using normal sugar for the preparation of portioned foods, the use of a low-GI sugar is encouraged as part of a wider plan for the management of diabetic patients.

scholarly journals Estimation of HbA1c value using artificial neural networks

2017 ◽  
Vol 7 (1) ◽  
pp. 1-7
Author(s):  
Musa Peker ◽  
Ali Sasar ◽  
Osman Ozkaraca ◽  
Gurbuz Akcay
Keyword(s):  
Neural Network ◽  
Blood Sugar ◽  
Accurate Estimation ◽  
Diabetic Patients ◽  
Haemoglobin A1c ◽  
Factors Affecting ◽  
High Hba1c ◽  
Artificial Neural ◽  
Artificial Neural Network Ann ◽  
Sugar Levels

Diabetes is a life-long disease that occurs because of ineffectiveness or lack of the insulin hormone. Although the blood sugar, fructose and haemoglobin A1c (HbA1c) values are commonly used for diagnosis, the latter give more accurate results. The HbA1c value gives information about the blood sugar levels over the past 2 to 3 months, which is required for treating diabetes. Follow-up data of diabetic patients have been used in this study. In the classification phase, a feed-forward artificial neural network (ANN) was used to estimate the factors affecting HbA1c. The designed ANN has 26 features used as input parameters. The output layer comprises two outputs: normal (HbA1c < 6.5) and high (HbA1c ≥ 6.5). An accuracy rate of 90.33% was obtained with the proposed method. The results, which show accurate estimation of the HbA1c level parameters, will be used in future studies to investigate which parameter affects the HbA1c levels, and in what way. Keywords: Neural network, haemoglobin A1c, diagnosis of diabetes disease

scholarly journals Garlic: an alternative in reducing blood glucose on diabetic patients

2020 ◽  
Vol 7 (6) ◽  
pp. 2078
Author(s):  
Putri Dafriani ◽  
Roza Marlinda ◽  
Eliza Arman ◽  
Meldafia Idaman
Keyword(s):  
Blood Sugar ◽  
Group Intervention ◽  
Blood Sugar Level ◽  
Intervention Group ◽  
Antidiabetic Drugs ◽  
Control Group ◽  
Diabetic Patients ◽  
Post Test ◽  
Quasi Experimental ◽  
Sugar Levels

Background: Diabetes mellitus (DM), a metabolic disorder characterized by an increasing of blood sugar (hyperglycemia). Medication is one of the seven pillars of diabetes managementt. Garlic (Allium sativum), an alternative herb, also has an antidiabetic effect. The purpose of this study was to investigate the effect of garlic on the blood sugar level in type 2 diabetes mellitus.Methods: This study was a quasi-experimental design with two group post-test design. The participants were DM patients who only take medication without any supplemental herbs. The respondents were divided into two group; intervention group, given antidiabetic drugs and consume garlic 3 pieces of garlic/day for 2 weeks and control group only got antidiabetic drugs. Data were collected by performing blood sugar measurement using glucose-check on all respondents using capillary blood in the fingertips. Second measurement were taken after monitoring the consumption of garlic together with drugs for two weeks. Hypothesis testing used independent T-Test test.Results: The study result found that the average of blood sugar level after administering the treatment is 240 mg/dl in the intervention group, and 284 mg/dl in control group. It can be concluded that the administration of 3 pieces of garlic combining with antidiabetic drugs for 2 weeks has not been able to reduce blood sugar levels into normal limits.Conclusions: This combination found to lowering the blood sugar levels in a significant amount compare to only drugs. The length of the therapy could consider as a significant predictor.

scholarly journals Correlation of Ankle-Brachial Index with Diabetic Retinopathy in Patients of Type 2 Diabetes

2020 ◽  
Vol 35 (4) ◽  
Author(s):  
Abdullah Mazhar ◽  
Tayyaba gul Malik ◽  
Aalia Ali ◽  
Hina Nadeem
Keyword(s):  
Type 2 Diabetes ◽  
Diabetic Retinopathy ◽  
Blood Sugar ◽  
Teaching Hospital ◽  
Ankle Brachial Index ◽  
Diabetic Patients ◽  
Duration Of Diabetes ◽  
Sugar Levels ◽  
Relationship Of

Objectives: To find out a relationship of diabetic retinopathy with ankle-brachial (ABI) in patients of type 2 diabetes. Material and Methods It was a cross-sectional observational study carried out in Arif Memorial Teaching hospital and Rashid Latif Medical College from January 2019 to June 2019. 120 patients were selected by purposive convenient sampling from outpatient department of Arif Memorial Teaching hospital. After clinical history, complete ocular examination was performed. Random blood sugar levels were measured using Glucometer. Ankle-brachial index was calculated by dividing the systolic pressure at ankle by the systolic blood pressure at arm. Statistical analysis was done using SPSS 25. Independent sample t test and chi square tests were used to find out the significance of the results. Results: In this study of 120 diabetic patients, 80 (66.7%) were female and 40 (33.3%) were males. Mean Ankle Branchial Index (ABI) of Males was 0.96±0.11 and for females was 0.97±0.14. Among 120 participants of this study, 73 (60.83 %) patients had no signs of diabetic retinopathy, 35 (29.16 %) patients had NPDR and 12 (10%) patients had PDR. ABI was not associated with gender and duration of diabetes. However, there was negative and weak linear relationship between BSR and ABI (r= -0.221). This correlation was higher in diabetics of less than 5 year duration (r=-0.286) than in patients of more than 5 years duration of diabetes (r=-0.129).  Conclusion: Our study indicates that ABI is not significantly related with diabetic retinopathy. However, there is a positive relationship of ABI with high blood sugar levels.

scholarly journals Impact of Music on Type 2 Diabetes

2016 ◽  
Vol 1 (1) ◽  
Keyword(s):  
Blood Sugar ◽  
Fasting Blood Glucose ◽  
Control Group ◽  
Diabetic Patients ◽  
Glucose Levels ◽  
Normal Category ◽  
Conventional Diet ◽  
Sugar Levels ◽  
In The Beginning ◽  
Experimental Group

The present study is undertaken to see the effect of music on blood sugar levels among type two diabetic patients. 100 diabetic patients aged 60-75 years were randomly selected from diabetic clinics. They are divided into two groups of 50 each (25 females and 25 males) one group served as control and another experimental. Both groups received regular conventional diet, medical protocol, and exercise/yoga. The experimental group was exposed daily to music of their choice approved by a music therapist for 40 minutes in addition. The study was undertaken for 3 months. Fasting blood glucose levels were taken in the beginning and after every month. The initial average blood sugar in the control group is 160 mg/dl and in the experimental group is 158mg/dl. Grouping them into various levels showed that initially none of the patients in both groups had normal blood sugar levels. In the experimental group those in the categories of 101-120 mg/dl are 16%, 121-140 mg/dl are 28%, 141-160 mg/dl are16% and those in >160 mg/dl are 48c% after 3 months 48% patients slided over to the normal category, in the other levels are 28%, 18%, 4% and 2% respectively. In the control group the corresponding levels are 4% in the normal category and 4%, 28%, 60%, and 4% respectively. The results indicated that there is consistent decrease in the fasting levels in the experimental group indicating that listening to music of their choice probably reduced the stress levels and thereby the blood sugar levels.

scholarly journals Low-Glycemic-Index Sugar in Type 2 Diabetic Patients: a Randomized Controlled Study

2021 ◽  
Author(s):  
Damien Steciuk ◽  
Samia Mahmood Hafez Amir ◽  
Aroushini Goorapah ◽  
Muzzammil Hosenally
Keyword(s):  
Blood Sugar ◽  
Glycemic Index ◽  
Glucose Monitoring ◽  
Controlled Study ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Sugar Levels ◽  
Type 2 Diabetic ◽  
Low Glycemic Index

Abstract Background and ObjectivesThere is a need to re assess the value of low-GI food and its specific components. The effect of one of them, namely low-glycemic-index sugar, is unclear, as its impact is usually confounded when reported in the literature. This study attempts to breach this gap, shedding light on its effect in type 2 diabetic patients and evaluate if it could be considered as part of a dietary plan.Subjects and MethodsThe blood sugar level of twenty (20) type 2 diabetics was monitored using a Continuous Glucose Monitoring system during two phases; firstly, an initial period of 5 days, whereby all the included patients were taking their usual dietary meals. Subjects were then randomized into two groups of equal size before embarking on a second phase; 10 subjects were instructed to eat prepared, portioned and delivered meals, the difference for the second group being that low-GI sugar was used for the preparation. ResultsCompared to baseline (day 1), blood sugar dropped by 18% for the group with low-GI sugar and 13% for those who consumed sugar with a normal-GI. The variation in sugar levels was also more contained in the interventional group. A by-product of the study design shows that constant glucose monitoring could raise awareness, and may foster reduction in blood sugar levels. Portioned food was capable of reducing blood sugar levels, with elevated levels of compliance just after start. ConclusionsEven though the ultimate aim is to reduce sugar consumption by diabetic patients, the intake of a low-GI sugar seems to be less harmful than normal sugar. Compared to using normal sugar for the preparation of portioned foods, the use of a low-GI sugar is encouraged as part of a wider plan for the management of diabetic patients.

Biochemical Parameters Determination for Prognosis of Retinal Diseases and their Relationship to Cataract, Diabetes and Hypertension Patients in Ibn Al-Haytham Hospital in Baghdad-Iraq

2021 ◽  
Vol 19 (5) ◽  
pp. 43-48
Author(s):  
Huda H. Hassan ◽  
Fayhaa M. Khaleel ◽  
Khuthear A. Al Taee
Keyword(s):  
Blood Sugar ◽  
Pathological Condition ◽  
Retinal Disease ◽  
Diabetic Patients ◽  
Retinal Diseases ◽  
Serum Retinol ◽  
Glucose Levels ◽  
Healthy Control ◽  
Sugar Levels ◽  
Cataract Patients

The role of serum retinol activity in association with the Blood sugar level, and their link as biochemical marker risk for lens inflammation and damage stage under pandemic, for the Retinal disease patients with cataract, hypertension, and diabetes, and in healthy for both genders. Total of seventy-five patients and thirty healthy control have been studied. Retinal disease patients were subdivided on the basis of pathological condition into three subgroups (First group was cataract, second was hypertension, and the third group was diabetes. Assessment, of serum retinol activity, and blood glucose levels were done for all groups. The concentricity of serum retinol levels is decreased in diabetic patients than control (13.147±7.195 (μmol/L) with 21.930±16.241 (μmol/L) versus P = 0.011)), while for cataract patients, they showed extremely similar concentricity of serum retinol levels to healthy (20.760±15.941 (μmol/L) with P = 0.790), whilst the retinol-activity was exhibited to be higher in hypertension patients (24.190±21.972 (μmol/L) versus P = 0.663). retinol activity is correlated significantly negatively with both diabetic patients and cataract. Moreover, blood sugar levels are increased in diabetes than control (10.256±4.119 (μmol/L) versus 5.365±1.084 (μmol/L) with P = 0.0001), in comparison with cataract (5.288±0.9560 (μmol/L) with P = 782). The retinol levels are correlated significantly negatively for diabetic and cataract patients. The purpose of this work: is to investigate association between retinal diseases with cataract hypertension & diabetes for risk of fasting at least eight hours in Ramadan and out of Ramadan time, and directly pre surgery gets started by artificial intraocular lens, and by estimation of retinol and blood sugar concentrations.

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