Fight/Flight Reaction

2010 ◽  
Author(s):  
Stanley Berent
Keyword(s):  
Flight Reaction

Autism Spectrum Disorder, Fear Response, and Environmental Exposures

2019 ◽  
pp. 30-51 ◽  
Author(s):  
Theoharis C. Theoharides ◽  
Jaanvi Sant ◽  
Maria-Eleni Giota
Keyword(s):  
Autism Spectrum Disorder ◽  
Mast Cells ◽  
Effective Treatment ◽  
Immune Cells ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Fear Response ◽  
Environmental Stimuli ◽  
Flight Reaction ◽  
Developmental Condition

Autism spectrum disorder (ASD) is a developmental condition characterized by impaired social interactions and communication, as well as by stereotypic movements, that affects 1 in 59 children. ASD is expected to reach 1 in about 40 children by 2020, yet it remains without distinct pathogenesis and effective treatment. Children with ASD respond with high anxiety to almost any unknown stimulus and appear to misread danger/threat signals, and may not experience anxiety in situations where normotypic children do. The authors propose that environmental stimuli stimulate the unique immune cells, known as mast cells (MC), which then trigger microglia, leading to dysfunctional neuronal connectivity in the amygdala. This process lowers or disrupts the “fear response” and leads to an exaggerated “fight-or-flight” reaction. corticotropin-releasing hormone (CRH) could have a synergistic effect with environmental stimuli, especially mycotoxins. Recognizing this association and preventing stimulation of mast cells/microglia could lead to effective treatment of ASD.

Genome‐wide association study identifies genomic loci associated with flight reaction in cattle

2019 ◽  
Vol 137 (5) ◽  
pp. 477-485
Author(s):  
Qiuming Chen ◽  
Fengwei Zhang ◽  
Kaixing Qu ◽  
Quratulain Hanif ◽  
Jiafei Shen ◽  
...  
Keyword(s):  
Association Study ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Genome Wide ◽  
Flight Reaction

Detection of Driver's Fight or Flight Reaction by Spatio-Temporal Spectrum Differential Analysis ofFacial Skin Thermogram

2010 ◽  
Vol 22 (1) ◽  
pp. 43-49
Author(s):  
Hirotoshi Asano ◽  
◽  
Hideto Ide
Keyword(s):  
Skin Temperature ◽  
Driving Simulator ◽  
Differential Analysis ◽  
Facial Skin ◽  
Car Accidents ◽  
Flight Reaction ◽  
Spatio Temporal ◽  
Car Accident ◽  
Biological Measurement ◽  
Fight Or Flight

Before a person has a car accident, he may have several “close calls.” These “close calls” may cause a person to experience tension and fear. People experience the “fight or flight reaction” (FFR) under such circumstances, as it is known that people exhibit the FFR when they feel anxiety, strain, or threat. If the manifestation of the FFR in a driver can be determined using a biological measurement, it would be an extremely effective indicator that might help in the prevention of car accidents. In this research, we conducted FFR-arousing experiments using a driving simulator, and the STSDA method was used to detect spatio-temporal changes in the skin temperature on facial skin thermograms accompanying the occurrence of the FFR.

The concept of cellular “fight-or-flight” reaction to stress

2001 ◽  
Vol 280 (4) ◽  
pp. F551-F561 ◽  
Author(s):  
Michael S. Goligorsky
Keyword(s):  
Essential Feature ◽  
Cellular Mechanisms ◽  
Cellular Survival ◽  
Cellular Events ◽  
Cell Matrix ◽  
Growing Body ◽  
Flight Reaction ◽  
Fight Or Flight Response ◽  
Cell Matrix Adhesion ◽  
Fight Or Flight

As animals respond to environmental stress with a set of default reactions described as the “fight-or-flight” response, so do epithelial and endothelial cells when they are confronting stressors in their microenvironment. This review will summarize a growing body of data suggesting the existence of a set of stereotypical cellular reactions to stress, provide some examples of diseases that are characterized by excessive flight reactions, describe the cellular mechanisms whereby the fight-or-flight reaction is accomplished, as well as cellular mechanisms triggering either fight or flight. It is proposed that cell-matrix adhesion is a sensitive indicator of the severity of stress. This indicator is interfaced with several default programs for cellular survival or death, thus dictating the fate of the cell. Some diagnostic and therapeutic applications of the concept, presently used and potentially useful, are outlined. The essential feature of this concept is its ability to categorize cellular events in terms of either type of default reaction, predict the details of each, and potentially exploit them clinically.

Stress Management For Good Physical And Mental Health

2017 ◽  
Vol 4 (2) ◽  
pp. 33-35
Author(s):  
K.D. Upadhyaya
Keyword(s):  
Negative Impact ◽  
External Pressure ◽  
Emotional Reaction ◽  
The Body ◽  
Physical And Mental Health ◽  
Cumulative Stress ◽  
Flight Reaction ◽  
Inner Strength ◽  
Fear And Anxiety ◽  
Risk Of Cancer

Stress can have a negative impact on just about every part of your body. It can suppress your immune system, cause a heart attack, or stroke, increase your risk of cancer, delay wound healing, promote inflammation, cause you to gain weight, impair your memory, cause depression, exacerbate diabetes and worsen your sexual function. Stress also makes you age faster….Dean Ornish MD : The Spectrum Stress is a physical or emotional reaction / response to any kind of change which may be external, internal or both. External pressure for example can be due to job stress, competition, challenges or frequently changing government policies etc. Internal pressure is mainly due to negative thoughts, fear, and anxiety. There is a individual variation in stress response. Many people have inner strength or resilience to manage day to day stress and cumulative stress well. People who have learned to manage stress also minimize the effect of stress. Those who do not have good inner strength and who have not learned the management of stress suffer a lot because of stress.Whenever there is stress, brain tells the body to release some chemicals so that the body is ready for the fight or flight reaction to deal with immediate danger.

Detour Experiments With Sticklebacks (Gasterosteus Aculeatus L.)

1931 ◽  
Vol 8 (4) ◽  
pp. 393-410
Author(s):  
E. S. RUSSELL
Keyword(s):  
Gasterosteus Aculeatus ◽  
Standard Test ◽  
Sudden Drop ◽  
Flight Reaction ◽  
To Come

The six individuals of Gasterosteus aculeatus tested learned to find their way into a small jar or bottle for food, and also learned how to come out. One failed in the standard test, with the jar upright. The solution was found at first by chance, but after a few trials the behaviour became definitely directed towards finding the solution. This change was accompanied by a sudden drop in the time taken; the jar also acquired significance, ceasing to be an indifferent object. The mode of solution was retained for over 3 months. The bearing of these results on the theory of learning is briefly discussed. The flight reaction shown by sticklebacks on sudden illumination is described.

scholarly journals Mast Cells, Stress, Fear and Autism Spectrum Disorder

2019 ◽  
Vol 20 (15) ◽  
pp. 3611 ◽  
Author(s):  
Theoharis C. Theoharides ◽  
Maria Kavalioti ◽  
Irene Tsilioni
Keyword(s):  
Autism Spectrum Disorder ◽  
Mast Cells ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Neuronal Connectivity ◽  
Environmental Stimuli ◽  
Flight Reaction ◽  
Developmental Condition ◽  
Synaptic Pruning ◽  
Stimulation Of

Autism Spectrum Disorder (ASD) is a developmental condition characterized by impaired communication and obsessive behavior that affects 1 in 59 children. ASD is expected to affect 1 in about 40 children by 2020, but there is still no distinct pathogenesis or effective treatments. Prenatal stress has been associated with higher risk of developing ASD in the offspring. Moreover, children with ASD cannot handle anxiety and respond disproportionately even to otherwise benign triggers. Stress and environmental stimuli trigger the unique immune cells, mast cells, which could then trigger microglia leading to abnormal synaptic pruning and dysfunctional neuronal connectivity. This process could alter the “fear threshold” in the amygdala and lead to an exaggerated “fight-or-flight” reaction. The combination of corticotropin-releasing hormone (CRH), secreted under stress, together with environmental stimuli could be major contributors to the pathogenesis of ASD. Recognizing these associations and preventing stimulation of mast cells and/or microglia could greatly benefit ASD patients.

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