Local Immune‐Triggered Surface‐Modified Stem Cells for Solid Tumor Immunotherapy

2019 ◽  
Vol 29 (26) ◽  
pp. 1900773 ◽  
Author(s):  
Kyoung Sub Kim ◽  
Joo Young Lee ◽  
Jieun Han ◽  
Hee Sook Hwang ◽  
Jonghwan Lee ◽  
...  
2019 ◽  
Vol 29 (26) ◽  
pp. 1970176 ◽  
Author(s):  
Kyoung Sub Kim ◽  
Joo Young Lee ◽  
Jieun Han ◽  
Hee Sook Hwang ◽  
Jonghwan Lee ◽  
...  

2014 ◽  
Vol 33 (1) ◽  
pp. 148-148
Author(s):  
Sonia SANTANDER ◽  
Clara ALCAINE ◽  
Jaber LYAHYAI ◽  
Maria Angeles PÉREZ ◽  
Clementina RODELLAR ◽  
...  

2014 ◽  
pp. 5389 ◽  
Author(s):  
Ai Wen Tan ◽  
Lelia Tay ◽  
Kien Hui Chua ◽  
Roslina Ahmad ◽  
Sheikh Ali Akbar ◽  
...  

2018 ◽  
Vol 13 (01) ◽  
pp. 19-28 ◽  
Author(s):  
David H. Margarit ◽  
Lilia Romanelli ◽  
Alejandro J. Fendrik

A model with spherical symmetry is proposed. We analyze the appropriate parameters of cell differentiation for different kinds of cells (Cancer Stem Cells (CSC) and Differentiated Cells (DC)). The plasticity (capacity to return from a DC to its previous state of CSC) is taken into account. Following this hypothesis, the dissemination of CSCs to another organ is analyzed. The location of the cells in the tumor and the plasticity range for possible metastasis is discussed.


Cells ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 1293 ◽  
Author(s):  
Ghmkin Hassan ◽  
Masaharu Seno

The concepts of hematopoiesis and the generation of blood and immune cells from hematopoietic stem cells are some steady concepts in the field of hematology. However, the knowledge of hematopoietic cells arising from solid tumor cancer stem cells is novel. In the solid tumor microenvironment, hematopoietic cells play pivotal roles in tumor growth and progression. Recent studies have reported that solid tumor cancer cells or cancer stem cells could differentiate into hematopoietic cells. Here, we discuss efforts and research that focused on the presence of hematopoietic cells in tumor microenvironments. We also discuss hematopoiesis from solid tumor cancer stem cells and clarify the notion of differentiation of solid tumor cancer stem cells into non-cancer hematopoietic stem cells.


Stem Cells ◽  
2009 ◽  
Vol 27 (3) ◽  
pp. 753-760 ◽  
Author(s):  
Marta Compte ◽  
Ángel M. Cuesta ◽  
David Sánchez-Martín ◽  
Vanesa Alonso-Camino ◽  
José Luís Vicario ◽  
...  

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