scholarly journals Adherence to the MIND diet and cognitive performance in the ELSA‐Brasil study

2021 ◽  
Vol 17 (S10) ◽  
Author(s):  
Naomi V Ferreira ◽  
Paulo A Lotufo ◽  
Isabela M Bensenor ◽  
Sandhi Maria Barreto ◽  
Maria Carmen Viana ◽  
...  
2020 ◽  
Author(s):  
Golnaz Arjmand ◽  
Mojtaba Abbas-Zadeh ◽  
Mohammad Hassan Eftekhari

AbstractBackground and AimPrevious studies suggested adherence to recently developed Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) associated with cognitive performance. There was no prior Randomized controlled Trial (RCT) to investigate this association. This study aimed to examine the effect of MIND dietary pattern on features of cognitive performance and also changes in brain structure in healthy obese women.MethodsAs a total of 50 obese women assessed for eligibility, we randomly allocated 40 participants with mean BMI 32 ± 4.31 and mean age 48 ± 5.38 years to either calorie-restricted modified MIND diet or a calorie-restricted standard control diet. Change in cognitive performance was the primary outcome measured with a comprehensive neuropsychological test battery. We also performed voxel-based morphometry as a secondary outcome to quantify the differences in brain structure. All of the measurements administered at baseline and three months follow up.ResultsThirty-seven participants (MIND group=22 and control group=15) completed the study. The results found in the MIND diet group working memory +1.37 (95% CI: 0.79,1.95), verbal recognition memory +4.85 (95% CI: 3.30,6.40), and attention +3.75 (95% CI: 2.43,5.07) improved more compared with the control group (ps < 0.05). Results of brain MRI consists of an increase in surface area of inferior frontal gyrus in the MIND diet group. Furthermore, the results showed a decrease in the cerebellum-white matter and cerebellum-cortex in two groups of study. Still, the effect in the MIND group was greater than the control group.ConclusionsThe study findings declare for the first time that the MIND diet intervention can reverse the destructive effects of obesity on cognition and brain structure, which could be strengthened by a modest calorie restriction.


2021 ◽  
pp. 1-13
Author(s):  
Debora Melo van Lent ◽  
Adrienne O’Donnell ◽  
Alexa S. Beiser ◽  
Ramachandran S. Vasan ◽  
Charles S. DeCarli ◽  
...  

Background: Adherence to the Mediterranean-DASH for Neurodegenerative Delay (MIND) diet has previously been associated with cognitive decline and dementia. To our knowledge, no prior study has investigated the association between the MIND diet and measures of brain volume, silent brain infarcts (SBIs), or brain atrophy. Objective: We evaluated whether adherence to the MIND diet associated with superior cognitive function, larger brain volumes, fewer SBIs, and less cognitive decline in the community-based Framingham Heart Study. Methods: 2,092 participants (mean±SD, age 61±9) completed Food Frequency Questionnaires, averaged across a maximum of 3-time points (examination cycles 5, 6, and 7), cognitive testing at examination cycle 7 (present study baseline: 1998–2001) and after a mean±SD of 6.6±1.1 years from baseline (n = 1,584). A subset of participants also completed brain magnetic resonance imaging (MRI) at examination cycle 7 (n = 1,904). In addition, participants with dementia, stroke, and other relevant neurological diseases such as significant head trauma, subdural hematoma, or multiple sclerosis were excluded from the analyses. Results: Higher MIND diet scores were associated with better global cognitive function (β±SE,+0.03SD±0.01; p = 0.004), verbal memory, visual memory, processing speed, verbal comprehension/reasoning, and with larger total brain volume (TBV) following adjustments for clinical, lifestyle and demographic covariates, but not with other brain MRI measures (i.e., hippocampal volume, lateral ventricular volume, white matter hyperintensity volume, SBIs) or cognitive decline. Conclusion: Higher MIND diet scores associated with better cognitive performance and larger TBV at baseline, but not with cognitive decline. Clinical trials are needed to ascertain whether adopting the MIND diet affects trajectories of cognitive decline.


2006 ◽  
Vol 14 (7S_Part_25) ◽  
pp. P1338-P1339
Author(s):  
Jayandra J. Himali ◽  
Debora Melo van Lent ◽  
Adrienne O'Donnell ◽  
Paul F. Jacques ◽  
Michael Wagner ◽  
...  

2017 ◽  
Vol 13 (7S_Part_17) ◽  
pp. P858-P858
Author(s):  
Kathleen M. Hayden ◽  
Yamin Wang ◽  
Daniel Beavers ◽  
Jiu-Chiuan Chen ◽  
Mark A. Espeland ◽  
...  

2020 ◽  
Author(s):  
Deirdre Timlin ◽  
Barbara Giannantoni ◽  
Jacqueline McCormack ◽  
Angela Polito Polito ◽  
Donatella Ciarapica Ciarapica ◽  
...  

Abstract Background: The aim of this study was to develop a “behavioural diagnosis” of factors influencing the uptake of the MIND diet in 40-55-year olds according to the COM-B model, in order to reduce the risk of cognitive decline in later life. Comparing a Mediterranean (Italy) and non-Mediterranean (Northern Ireland) country to inform an intervention. This study also sought to identify intervention functions and behaviour change techniques (BCTs) that are likely to be effective in changing MIND diet behaviour. Methods: This was a qualitative study that was used to elicit beliefs surrounding Capability, Opportunity, Motivation and Behaviour (COM-B) with adhering to a diet associated with a reduced risk of cognitive decline, the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND diet). This study further elaborated the COM-B components into the 14 domains of the Theoretical Domains Framework (TDF) to further understand behaviour. Twenty-five Northern Irish (NI) and Italian participants were recruited onto the study, to take part in either a focus group or an interview. Participants were both male and female aged between 40-55 years. Results: Thematic analysis revealed that the main barriers to the uptake of the MIND diet were; time, work environment (opportunity), taste preference and convenience (motivation). Culture (motivation), seasonal foods and lack of family support (opportunity) to be a barrier to the Italian sample only. The main facilitators reported were; improved health, memory, planning and organisation (motivation) and access to good quality food (opportunity). Cooking skills, knowledge (capability) and heathy work lunch (opportunity) being a facilitator to the Italian sample only. Five intervention functions and fifteen BCTs were identified for possible inclusion in intervention development. Conclusions: The “behavioural diagnosis” provides comparisons and valuable insight into the personal, social and environmental factors that participants report as barriers and facilitators to the uptake of the MIND diet in the two samples. More barriers to healthy dietary change were found than facilitators. There is a need for interventions that increase capability, opportunity and motivation to aid behaviour change. The “behavioural diagnosis” from this study will be used to design a behaviour change intervention using the subsequent steps from the Behaviour Change Wheel (BCW).


2020 ◽  
Author(s):  
Avril Metcalfe-Roach ◽  
Adam Yu ◽  
Ella Golz ◽  
Kristen Sundvick ◽  
Mihai Cirstea ◽  
...  

Background: The MIND diet has been linked with prevention of Alzheimer's disease and cognitive decline but has not been fully assessed in the context of Parkinson's disease (PD). Objective: To determine whether MIND diet adherence is associated with the age of Parkinson's disease onset in a manner superior to that of the Mediterranean diet. Methods: Food Frequency Questionnaires from 167 participants with PD and 119 controls were scored for MIND and two versions of Mediterranean diet adherence. Scores were compared between sex and disease subgroups, and PD diet adherence was correlated with age of onset using univariate and multivariate linear models. Results: The female subgroup adhered more closely to the MIND diet than the males, and diet scores were not modified by disease status. Later age of onset correlated most strongly with MIND diet adherence in the female subgroup, corresponding to differences of up to 17.4 years (p<0.001) between low and high dietary tertiles. Greek Mediterranean adherence was also significantly associated with later PD onset across all models (p=0.05-0.03). Conversely, only Greek Mediterranean adherence remained correlated with later onset across all models in men, with differences of up to 8.4 years (p=0.002). Conclusions: This cross-sectional study finds a strong correlation of age of onset of PD with dietary habits, suggesting that nutritional strategies may be an effective tool to delay PD onset. Further studies may help to elucidate potential nutrition-related sex-specific pathophysiological mechanisms and differential prevalence rates in PD.


2020 ◽  
pp. 1-8
Author(s):  
Sanaz Soltani ◽  
Mehdi Shayanfar ◽  
Sanaz Benisi-Kohansal ◽  
Minoo Mohammad-Shirazi ◽  
Giuve Sharifi ◽  
...  

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