scholarly journals Antihyperglycemic and antidyslipidemic activity ofMusa paradisiaca-based diet in alloxan-induced diabetic rats

2017 ◽  
Vol 6 (1) ◽  
pp. 137-145 ◽  
Author(s):  
Basiru O. Ajiboye ◽  
Hussein O. B. Oloyede ◽  
Musa O. Salawu
Keyword(s):  
Diabetic Rats ◽  
Antidyslipidemic Activity

Blend of selected fruit extracts shows antidiabetic effect by enhanced insulin secretion, modulation of β-cell function, and antidyslipidemic activity in type 2 diabetic rats

2013 ◽  
Vol 23 (6) ◽  
pp. 1661-1667 ◽  
Author(s):  
Ochuko L. Erukainure ◽  
Oluwatoyin Okafor ◽  
Atinuke Ajayi ◽  
Okukwe C. Obode ◽  
Oluwakemi Daramola ◽  
...  
Keyword(s):  
Insulin Secretion ◽  
Cell Function ◽  
Diabetic Rats ◽  
Β Cell ◽  
Antidiabetic Effect ◽  
Fruit Extracts ◽  
Β Cell Function ◽  
Antidyslipidemic Activity ◽  
Type 2 Diabetic

scholarly journals Aktivitas antidislipidemia Tepung tempe dan susu kedelai pada profil lipid tikus diabetes yang diinduksi streptozotocin

2017 ◽  
Vol 4 (3) ◽  
pp. 147 ◽  
Author(s):  
Kartika Nugraheni ◽  
Siti Harnina Bintari
Keyword(s):  
Lipid Profile ◽  
Ldl Cholesterol ◽  
Hdl Cholesterol ◽  
Diabetic Control ◽  
Diabetic Rats ◽  
Sprague Dawley ◽  
Fermented Soybean ◽  
Sprague Dawley Rats ◽  
The Difference ◽  
Antidyslipidemic Activity

<p><strong>ABSTRACT</strong></p><p><strong>Background :</strong> dyslipidemia increases risk of cardiovascular disease on diabetes patients. Soybean contain many bioactive compounds which can help control lipid profile.</p><p><strong>Objectives :</strong> analyze the difference between fermented soybean (tempe flour) and unfermented soybean (soymilk) on lipid profile in diabetic rats.</p><p><strong>Methods : </strong>thirty male sprague dawley rats divided into 3 groups (1) diabetic control (2) tempe flour 1,8 gr (3) soymilk 1,35 gr. Tempe flour and soymilk were given for 28 days. Profile lipid measured including total cholesterol, triglycerides, LDL cholesterol and HDL cholesterol. The data then were analyzed using Anova with confidence level of 95%.</p><p><strong>Results :</strong> the decrease values of total cholesteril, triglycerides and LDL cholesterol were better in tempe flour group (p&lt;0,05). In addition, tempe flour group also showed better increase in the value of HDL cholesterl (p&lt;0,05)</p><strong>Conclusion :</strong>fermented soybean (tempe flour) showed better antidyslipidemic activity than unfermented ones<p> </p>

Sites of Insulin Action Using Ferritin Labeling

1971 ◽  
Vol 29 ◽  
pp. 540-541
Author(s):  
Burton B. Silver ◽  
Ronald S. Nelson
Keyword(s):  
Electron Microscopy ◽  
Binding Sites ◽  
Anterior Pituitary ◽  
Insulin Action ◽  
Diabetic Rats ◽  
Insulin Antibody ◽  
Fat Pad ◽  
Target Organs ◽  
Uranium Salts ◽  
Sugar Levels

Some investigators feel that insulin does not enter cells but exerts its influence in some manner on the cell surface. Ferritin labeling of insulin and insulin antibody was used to determine if binding sites of insulin to specific target organs could be seen with electron microscopy.Alloxanized rats were considered diabetic if blood sugar levels were in excess of 300 mg %. Test reagents included ferritin, ferritin labeled insulin, and ferritin labeled insulin antibody. Target organs examined were were diaphragm, kidney, gastrocnemius, fat pad, liver and anterior pituitary. Reagents were administered through the left common carotid. Survival time was at least one hour in test animals. Tissue incubation studies were also done in normal as well as diabetic rats. Specimens were fixed in gluteraldehyde and osmium followed by staining with lead and uranium salts. Some tissues were not stained.

A PPARψ agonist improved diabetic state via decreasing TNF-α without any change including obesity in genetically obese diabetic rats

2001 ◽  
Vol 120 (5) ◽  
pp. A674-A674 ◽  
Author(s):  
A FUNAKOSHI ◽  
M ICHIKAWA ◽  
Y SATO ◽  
S KANAI ◽  
M OHTA ◽  
...  
Keyword(s):  
Diabetic Rats ◽  
Diabetic State ◽  
Tnf Α ◽  
Obese Diabetic Rats

791: Endothelial Rehabilitation - The Impact of Chronic PDE5 Inhibitors on Erectile Function and Protein Alterations in Cavernous Tissue of Diabetic Rats

2007 ◽  
Vol 177 (4S) ◽  
pp. 264-265
Author(s):  
Ling De Young ◽  
KokBin Lim ◽  
Jeffery Carson ◽  
Trustin Domes ◽  
Mussa Al-Numi ◽  
...  
Keyword(s):  
Erectile Function ◽  
Diabetic Rats ◽  
Pde5 Inhibitors ◽  
Cavernous Tissue ◽  
Protein Alterations ◽  
The Impact

Abstract # P-9: Bauhinia Variegata Decreases Renal Damage in Streptozotocin Induced Diabetic Rats

2016 ◽  
Vol 22 ◽  
pp. 17-18
Author(s):  
Mayuresh S. Garud ◽  
Yogesh A. Kulkarni
Keyword(s):  
Renal Damage ◽  
Diabetic Rats ◽  
Bauhinia Variegata

Effects of Maternal Flaxseed Supplementation on Female Offspring of Diabetic Rats in Serum Concentration of Glucose, Insulin, and Thyroid Hormones

2019 ◽  
Vol 89 (1-2) ◽  
pp. 45-54
Author(s):  
Akemi Suzuki ◽  
André Manoel Correia-Santos ◽  
Gabriela Câmara Vicente ◽  
Luiz Guillermo Coca Velarde ◽  
Gilson Teles Boaventura
Keyword(s):  
Thyroid Hormones ◽  
High Fat Diet ◽  
Female Offspring ◽  
Flaxseed Oil ◽  
Diabetic Rats ◽  
High Fat ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Flaxseed Flour ◽  
Maternal Consumption

Abstract. Objective: This study aimed to evaluate the effect of maternal consumption of flaxseed flour and oil on serum concentrations of glucose, insulin, and thyroid hormones of the adult female offspring of diabetic rats. Methods: Wistar rats were induced to diabetes by a high-fat diet (60%) and streptozotocin (35 mg/kg). Rats were mated and once pregnancy was confirmed, were divided into the following groups: Control Group (CG): casein-based diet; High-fat Group (HG): high-fat diet (49%); High-fat Flaxseed Group (HFG): high-fat diet supplemented with 25% flaxseed flour; High-fat Flaxseed Oil group (HOG): high-fat diet, where soya oil was replaced with flaxseed oil. After weaning, female pups (n = 6) from each group were separated, received a commercial rat diet and were sacrificed after 180 days. Serum insulin concentrations were determined by ELISA, the levels of triiodothyronine (T3), thyroxine (T4) and thyroid-stimulating hormone (TSH) were determined by chemiluminescence. Results: There was a significant reduction in body weight at weaning in HG (−31%), HFG (−33%) and HOG (44%) compared to CG (p = 0.002), which became similar by the end of 180 days. Blood glucose levels were reduced in HFG (−10%, p = 0.044) when compared to CG, and there was no significant difference between groups in relation to insulin, T3, T4, and TSH after 180 days. Conclusions: Maternal severe hyperglycemia during pregnancy and lactation resulted in a microsomal offspring. Maternal consumption of flaxseed reduces blood glucose levels in adult offspring without significant effects on insulin levels and thyroid hormones.

Hypoglycemic and antidiabetic activity of leaves of Aegle marmelose in normoglycemic and streptozotocin induced diabetic rats

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
AR Juvekar ◽  
DD Bandawane ◽  
MP Kulkarni ◽  
MR Juvekar
Keyword(s):  
Diabetic Rats ◽  
Antidiabetic Activity

Trichosanthes dioica mediated biochemical alterations in STZ induced diabetic rats

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
DK Rai ◽  
PK Rai ◽  
B Sharma ◽  
G Watal
Keyword(s):  
Diabetic Rats ◽  
Biochemical Alterations ◽  
Trichosanthes Dioica
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