Comparison of cross-sectional and longitudinal measurements of age-related changes in bone mineral content

2009 ◽  
Vol 4 (3) ◽  
pp. 351-357 ◽  
Author(s):  
James W. Davis ◽  
Philip D. Ross ◽  
Richard D. Wasnich ◽  
Charles J. Maclean ◽  
John M. Vogel
1993 ◽  
Vol 30 (11) ◽  
pp. 958-963
Author(s):  
Munehiko Tanno ◽  
Tetsuya Horiuchi ◽  
Takanori Yokoyama ◽  
Mari Ogihara ◽  
Mutsumi Kawakami ◽  
...  

Author(s):  
Annie M. Constable ◽  
Josie E. Porter ◽  
Danielle Benger ◽  
Dimitris Vlachopoulos ◽  
Alan R. Barker ◽  
...  

Purpose: Moderate-to-vigorous physical activity (MVPA) positively influences bone mineral content (BMC) in prepubertal children, but it is unknown whether this relationship is partially mediated by free leptin index. The aim of this study was to examine whether the relationship between MVPA and total body less head (TBLH) BMC is mediated or moderated by free leptin index in prepubertal children. Methods: We performed a cross-sectional analysis on 401 children (194 girls) from baseline examinations of the Physical Activity and Nutrition in Childhood Study. We applied the four-way decomposition mediation analysis method to assess whether free leptin index, measured from fasted blood samples, mediated the relationship between accelerometer-measured MVPA and TBLH BMC measured by dual-energy X-ray absorptiometry. Results: MVPA had a positive controlled direct effect on TBLH BMC in girls and boys (β = 0.010 to 0.011, p < 0.05). There was no mediation or interaction between MVPA, free leptin index and TBLH BMC in girls or boys (β = −0.000 to 0.001, p > 0.05). Conclusion: Our study indicates that MVPA positively influences TBLH BMC through pathways not related to free leptin index in predominantly normal-weight prepubertal children, likely primarily through mechanical loading. The relationships between MVPA, free leptin index and TBLH BMC may be influenced by other factors such as pubertal status and adiposity, so it is unknown whether these observations extend to overweight and obese children at different stages of puberty.


1997 ◽  
Vol 61 (2) ◽  
pp. 134-138 ◽  
Author(s):  
M. Revilla ◽  
L. F. Villa ◽  
A. Sánchez-Atrio ◽  
E. R. Hernández ◽  
H. Rico

2008 ◽  
Vol 104 (4) ◽  
pp. 1116-1120 ◽  
Author(s):  
Yoshihisa Umemura ◽  
Seigo Nagasawa ◽  
Naota Sogo ◽  
Akiko Honda

We investigated whether the effects of jump training on bone are preserved after a detraining period in female normal and estrogen-deficient rats. Forty-four 11-wk-old Wistar rats were divided into the following four groups: sham sedentary ( n = 12), sham exercised ( n = 11), ovariectomized sedentary ( n = 10), and ovariectomized exercised ( n = 11). An 8-wk exercise period was introduced in which the rats in the exercised groups were jumped 10 times/day, 5 days/wk. This was followed by 24 wk of detraining. At the end of the exercise period, the jump training significantly increased the bone mineral content of the tibia ( P < 0.001), measured by dual-energy X-ray absorptiometry. After the detraining period, the bone mineral content ( P < 0.01), strength ( P < 0.001), and cross-sectional widths ( P < 0.001) of the tibia in the exercised groups were still greater than in the sedentary groups, without significant surgery-exercise interactions, although bone stiffness in the fracture test ( P < 0.05) and bone area in the center-proximal region, as measured by dual-energy X-ray absorptiometry ( P < 0.05), showed significant surgery-exercise interactions. These findings suggest that the exercise effect on bone strength is preserved, accompanied by cross-sectional morphological changes, even under estrogen deficiency.


Bone ◽  
1992 ◽  
Vol 13 (2) ◽  
pp. 191-195 ◽  
Author(s):  
B. Jónsson ◽  
K. Ringsberg ◽  
P.O. Josefsson ◽  
O. Johnell ◽  
M. Birch-Jensen

2014 ◽  
Vol 111 (8) ◽  
pp. 1340-1360 ◽  
Author(s):  
Yvan Vandenplas ◽  
Pedro Gutierrez Castrellon ◽  
Rodolfo Rivas ◽  
Carlos Jimenez Gutiérrez ◽  
Luisa Diaz Garcia ◽  
...  

Soya-based infant formulas (SIF) containing soya flour were introduced almost 100 years ago. Modern soya formulas are used in allergy/intolerance to cows' milk-based formulas (CMF), post-infectious diarrhoea, lactose intolerance and galactosaemia, as a vegan human milk (HM) substitute, etc. The safety of SIF is still debated. In the present study, we reviewed the safety of SIF in relation to anthropometric growth, bone health (bone mineral content), immunity, cognition, and reproductive and endocrine functions. The present review includes cross-sectional, case–control, cohort studies or clinical trials that were carried out in children fed SIF compared with those fed other types of infant formulas and that measured safety. The databases that were searched included PubMed (1909 to July 2013), Embase (1988 to May 2013), LILACS (1990 to May 2011), ARTEMISA (13th edition, December 2012), Cochrane controlled trials register, Bandolier and DARE using the Cochrane methodology. Wherever possible, a meta-analysis was carried out. We found that the anthropometric patterns of children fed SIF were similar to those of children fed CMF or HM. Despite the high levels of phytates and aluminium in SIF, Hb, serum protein, Zn and Ca concentrations and bone mineral content were found to be similar to those of children fed CMF or HM. We also found the levels of genistein and daidzein to be higher in children fed SIF; however, we did not find strong evidence of a negative effect on reproductive and endocrine functions. Immune measurements and neurocognitive parameters were similar in all the feeding groups. In conclusion, modern SIF are evidence-based safety options to feed children requiring them. The patterns of growth, bone health and metabolic, reproductive, endocrine, immune and neurological functions are similar to those observed in children fed CMF or HM.


Sign in / Sign up

Export Citation Format

Share Document