Clinical value of 2D speckle tracking imaging in evaluating the effect of percutaneous intramyocardial septal radiofrequency ablation in patients with hypertrophic obstructive cardiomyopathy

Author(s):  
Dajun Qian ◽  
Xiaojun Zhou ◽  
Huan Liu ◽  
Lijun Cao
Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Meihua Zhu ◽  
Cole Streiff ◽  
Tao He ◽  
Muhammad Ashraf ◽  
Jiahui Zhang ◽  
...  

Introduction: Obesity may affect cardiac function, which is hard to detect by traditional echocardiography in the early stages. Speckle tracking imaging (STI) is sensitive to subtle myocardial dysfunction. The aim of this study was to determine the influence of obesity on left ventricular (LV) myocardial function in diet-induced obesity (DIO) mice using two-dimensional (2D) speckle tracking echocardiography (STE). Hypothesis: 2D STE is useful to detect obesity-caused myocardial dysfunction. Methods: Twenty newborn mice were divided into two groups: a DIO group (high-fat diet) and a control group (regular-fat diet). 2D image loops were acquired at the end of each month for 6 months. Global longitudinal strain (GLS) and global circumferential strain (GCS) were analyzed at feeding periods over 3 months and 6 months, and compared between the two groups. Results: The control group gained 64% of its initial weight, while the DIO group gained 82% of its initial weight at the 3 month feeding period; and the two groups gained 88% (control) and 125% (DIO) respectively at 6 months. STE analysis revealed an insignificant decrease in strain values in the DIO mice after 3 months; however, after 6 months, the DIO group demonstrated a significant decrease in strain values (P<0.05) despite normal ejection fractions in both groups. Conclusions: 2D STE is highly feasible to detect the myocardial dysfunction caused by obesity in earlier stage. These strain values appear to be related to the severity of obesity.


2017 ◽  
Vol 9 (8) ◽  
pp. 1
Author(s):  
Hiromi Shinno ◽  
Satoshi Kurose ◽  
Yutaka Yamanaka ◽  
Yaeko Fukushima ◽  
Hiromi Tsutsumi ◽  
...  

BACKGROUND: During static stretching, a muscle extends longitudinally, and blood vessels seem to extend simultaneously. However, it is difficult to visualize, and few findings have seen. The recent progress with ultrasonography enables measurements of movement in vivo using 2D speckle tracking imaging, as well as detailed evaluation of extension in tissues at the same site. The aim of this study is to evaluate longitudinal extension of blood vessels during static stretching using this methodology.METHODS: Participants were 10 healthy female volunteers (age of 39.4±11.6). They extended their right wrist with elbow extended. Then the ulnar artery was measured by using 2D speckle tracking imaging with a general-purpose ultrasound instrument. Tissue extension per unit time at the stretching site was calculated from before stretching to maximum of stretching. Simultaneous changes in the caliber of blood vessels during stretching were measured using ultrasound M-mode.RESULTS: The maximum angle of wrist extension was 0 to 83.6±12.5°. The muscle extended by 3.80±1.65% per unit time during stretching, and blood vessels simultaneously extended by 3.20±1.96%. These changes were significant compared to measurements before stretching (p<0.01) and shows the correlation between muscles and blood vessels (r=0.56, p=0.1). The calibers of blood vessels per unit time before and during stretching were 2.24±0.27 and 1.64±0.53 mm with a significant decrease during stretching (p<0.01).CONCLUSIONS: Imaging of static stretching showed extension of both the muscle/skeletal system and blood vessels longitudinally. The finding suggests that endothelial function might be activated by mechanical stress on vascular endothelial cells.


2017 ◽  
Vol 1 (Issue 1) ◽  
Author(s):  
Oben Baysan ◽  
Ezgi Ocaklı ◽  
Tugba Altuner ◽  
Sinan Kocaman

Left and right atria have gained interest from scientific community. Two or three- dimensional echocardiographic methods have been implemented for better understanding of atrial functions in both healthy persons and patients with various diseases. Atrial volume could be calculated from 2D or 3D images. Volumetric data and derived parameters could be used for determining atrial phasic functions. Nowadays, atrial deformation imaging with 2D-TDI, 2D-speckle tracking imaging or with recently introduced 3D speckle tracking is possible. All those methods have some advantages and disadvantages, which define their clinical value in the future.


2010 ◽  
Vol 6 (4) ◽  
pp. 16 ◽  
Author(s):  
Florim Cuculi ◽  
Michel Zuber ◽  
Paul Erne ◽  
◽  
◽  
...  

The introduction of speckle tracking imaging and the opportunity to objectify regional myocardial function in an angle-independent fashion has opened a wide array of opportunities. Quantitative echocardiography is likely to reduce intra-observer variability and shorten learning curves and this will allow broader use of these new imaging modalities in clinical routine and for research purposes. Tissue Doppler is used for deformation imaging, but has disadvantages that can be overcome with 2D speckle tracking. This article briefly summarises the technical details of 2D speckle tracking (strain and strain rate) and gives an overview on current and potential future applications of this new technique at rest and during stress.


2011 ◽  
Vol 38 (S1) ◽  
pp. 143-144
Author(s):  
F. Crispi ◽  
E. Sepúlveda-Swatson ◽  
J. Rojas-Benavente ◽  
M. C. Cruz Lemini ◽  
M. Sitges ◽  
...  

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Anders Hodt ◽  
Marie Stugaard ◽  
Jonny Hisdal ◽  
Einar Stranden ◽  
Dan Atar ◽  
...  

Background: The main purpose of this study was by novel 2D speckle tracking imaging (STI) to determine regional distribution of circumferential shortening, rotation and torsion (twist) and their relation to area ejection fraction (EF) during isovolumic contraction (IVC) and ejection phases in the normal left ventricle (LV). Methods: Twelve healthy subjects (22 ±3 years) were included. M-mode of atrio-ventricular level was used to describe LV longitudinal shortening, while circumferential strain, rotation and area EF were determined at four different LV short axis levels (basal, papillary, sub-papillary, apical) by STI. LV torsion was calculated as apical minus basal rotation. Results: See figure . During IVC, LV torsion demonstrated an “untwist pattern”, and LV shortened more in longitudinal than in circumferential direction. During ejection, the counter clockwise rotation increased from papillary level towards apex, −0.4 ± 3.3° and 9.6 ± 3.4° (p<0.05), respectively, while circumferential shortening was larger in apex than papillary level, −25.4 ± 5.0 and −19.3 ± 2.4% (p<0.05), respectively. EF increased from papillary level to apex, 52 ± 6.1 % and 65 ± 8.4 % (p<0.05), respectively. Conclusion: This study has showed a regional nonuniform pattern of rotation and circumferential shortening, with corresponding changes in regional EF in normal LV through systole. The increased counter clockwise rotation and circumferential shortening towards apex during ejection may be of mechanistic importance for distribution of blood towards LV outflow tract. The greater extent of longitudinal- than circumferential shortening and untwisting suggest a LV spherical form during IVC.


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