Deficits in Muscle Strength and Physical Performance Influence Physical Activity in Sarcopenic Children After Liver Transplantation

2020 ◽  
Vol 26 (4) ◽  
pp. 537-548
Author(s):  
Poh Hwa Ooi ◽  
Vera C. Mazurak ◽  
Kerry Siminoski ◽  
Ravi Bhargava ◽  
Jason Y. K. Yap ◽  
...  
2017 ◽  
Vol 27 (5) ◽  
pp. 579-596 ◽  
Author(s):  
E. Segura-Ortí ◽  
P. L. Gordon ◽  
J. W. Doyle ◽  
K. L. Johansen

The aim of this study was to determine the extent to which poor physical functioning, low participation in physical activity, and muscle atrophy observed among patients on hemodialysis are evident in the earlier stages of chronic kidney disease (CKD). We enrolled adults in three groups: no CKD, Stages 3 to 4 CKD, and hemodialysis. Outcomes measured were physical activity, muscle size, thigh muscle strength, physical performance, and self-reported physical function. Patients with CKD had muscle area intermediate between the no CKD and hemodialysis groups, but they had low levels of physical activity that were similar to the hemodialysis group. Physical activity and muscle size were significantly associated with all outcomes. Kidney function was not significantly associated with muscle strength or physical performance after adjustment for physical activity and muscle size. In conclusion, interventions aimed to increase muscle mass and energy expenditure might have an impact on improving physical function of CKD patients.


2020 ◽  
Vol 3 (1) ◽  
pp. 10
Author(s):  
Aulia Ramadhani ◽  
Taufan Bramantoro ◽  
Fridaniyanti Khusnul Khotimah ◽  
Lintang Maudina Santosa ◽  
Nancy Cynthia Sudiartha ◽  
...  

Background: An epidemiological study on elderly conducted by the PKL group number 6 in Jagir Health Public HealthCenter showed that periodontitis was linked hypertension, low muscle strength, and low physical activity, and carieswere linked to low muscle strength and low physical activity. Purpose: To create an informational health video aboutdental and oral health and physical performance in the elderly because there was none. Methods: The program wasconducted on Monday, 22 July 2019, at the Jagir Public Health Center using individual interviews. Results: Of the 20respondents, 5% of them disagreed, 5% quite agreed, 20% agreed, 70% strongly agreed that SEIMUT PERSIA helpedthem learn about dental and oral health and physical performance in the elderly. Out of the 20 respondents, 5% of themquite agreed, 15% agreed, and 80% strongly agreed that the SEIMUT PERSIA video was interesting to watch. Out of the20 respondents, 5% of them quite agreed, 20% agreed, and 75% strongly agreed that the SEIMUT PERSIA video was easyto digest. Conclusion: The respondents were interested in the information about dental and oral health and the physicalperformance of the elderly, and the video was easy to understand.


2017 ◽  
Vol 73 (1) ◽  
pp. 95-101 ◽  
Author(s):  
Davis A Englund ◽  
Dylan R Kirn ◽  
Afsaneh Koochek ◽  
Hao Zhu ◽  
Thomas G Travison ◽  
...  

Abstract Background Nutritional supplementation and physical activity have been shown to positively influence muscle mass and strength in older adults. The efficacy of long-term nutritional supplementation in combination with physical activity in older adults remains unclear. Methods Mobility-limited (short physical performance battery [SPPB] ≤9) and vitamin D insufficient (serum 25(OH) D 9–24 ng/mL) older adults were recruited for this study. All subjects participated in a physical activity program. Subjects were randomized to consume a daily nutritional supplement (150 kcal, 20 g whey protein, 800 IU vitamin D, 119 mL beverage) or placebo (30 kcal, nonnutritive, 119 mL). In a prespecified secondary analysis, we examined total-body composition (dual energy X-ray absorptiometry), thigh composition (computed tomography), and muscle strength, power, and quality before and after the 6-month intervention. Results One hundred and forty-nine subjects were randomized into the study [mean (standard deviation, SD) age 78.5 (5.4) years; 46.3% female; mean (SD) short physical performance battery 7.9 (1.2); mean (SD) vitamin D 18.7 (6.4) ng/mL]. After the intervention period both groups demonstrated improvements in muscle strength, body composition, and thigh composition. Nutritional supplementation lead to further losses of intermuscular fat (p = .049) and increased normal muscle density (p = .018). Conclusions Six months of physical activity resulted in improvements in body composition, subcutaneous fat, intermuscular fat, and strength measures. The addition of nutritional supplementation resulted in further declines in intermuscular fat and improved muscle density compared to placebo. These results suggest nutritional supplementation provides additional benefits to mobility-limited older adults undergoing exercise training. ClinicalTrials.gov Identifier: NCT01542892


2021 ◽  
Vol 50 (Supplement_1) ◽  
pp. i7-i11
Author(s):  
K J Bowden-Brown ◽  
J C Murray ◽  
C Hurst ◽  
A Granic ◽  
A A Sayer ◽  
...  

Abstract Introduction We established the MASS_Lifecourse study to investigate changes in skeletal muscle between ages 45–85. Reduced physical activity (PA) is a key factor linked to the development of sarcopenia. Our aim was the describe the amount and patterns of PA and sedentary behaviour (SB), and relationships with muscle strength and quantity, among MASS_Lifecourse participants. Method Participants wore a triaxial accelerometer on their dominant wrist for seven days. Recordings were analysed to calculate time in moderate-vigorous PA (MVPA) with time not in MVPA classified as SB based on wrist position. Muscle strength was measured with a Jamar grip dynamometer and the 5 chair-stand test. Muscle quantity was assessed using appendicular lean muscle mass from dual-energy X-ray absorptiometry. Physical performance was assessed by gait speed. Results 68 participants (31 male) aged 47–84 (mean 65) participated in the present study. Median daily MVPA was 19.1 (IQR 7.1, 36.6) minutes and was lower with age. The mean sedentary time per day was 767.1 minutes per day and increased with age. The pattern of MVPA across the day changed with age: the oldest group (75–84 years) achieved a lower morning activity peak followed by an earlier decline whilst the younger groups were more consistently active throughout the day. Participants were more active than population reference data from the Active Lives Survey. Time spent in MVPA was positively associated with muscle strength and physical performance, whereas SB was negatively associated. Muscle quantity was not associated with PA or SB. Conclusions Participants in the MASS_Lifecourse study are more active than the general population but still show age-related declines in physical activity and strength. Future work in the cohort aims to elucidate mechanisms underlying the age-related loss of muscle strength and quantity.


2016 ◽  
Author(s):  
Antimo Moretti ◽  
Sire Alessandro de ◽  
Dario Calafiore ◽  
Raffaele Gimigliano ◽  
Francesca Gimigliano ◽  
...  

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