The role of experimental toxicology in safety evaluation: Challenges facing the pharmaceutical industry

1990 ◽  
Vol 10 (2) ◽  
pp. 271-280 ◽  
Author(s):  
John C. Kapeghian ◽  
Vincent M. Traina
2021 ◽  
pp. 71-78
Author(s):  
Irina Anatolievna Selivanova ◽  
Roman Petrovich Terekhov ◽  
Amir Khalilovich Taldaev

The role of organic chemistry and other chemical disciplines in the system of training qualified personnel for the pharmaceutical industry is indisputable. In what direction is chemistry developing in the modern world? What innovative directions does chemistry offer to drug developers? Can a robot synthesize a new compound? How to achieve practically significant results of scientific research? How may the obtained results be published in highly rated journals? These and many other topics were widely discussed at the XII International Conference of Students and Young Scientists in Chemistry «Mendeleev-2021» held in the fall of 2021. This article is published to attract young researchers’ attention to topical issues at the interface of chemistry and pharmacy and assist them in realizing their creative scientific potential.


2022 ◽  
Vol 4 (1) ◽  
pp. 013-018
Author(s):  
Mohini Chandrashekhar Upadhye ◽  
Mohini Chetan Kuchekar ◽  
Rohini Revansiddhappa Pujari ◽  
Nutan Uttam Sable

Biopolymers are compounds prepared by using various living organisms, including plants. These are composed of repeated units of the same or similar structure (monomers) linked together. Rubber, starch, cellulose, proteins and DNA, RNA, chitin, and peptides are some of the examples of natural biopolymers. Biopolymers are a diverse and remarkably versatile class of materials that are either produced by biological systems or synthesize from biological sources. Biopolymers are used in pharmaceutical industry and also in food industry.Naturally derived polymers are also used for conditioning benefits in hair and skin care. Biopolymers have various applications in medicine, food, packaging, and petroleum industries. This review article is focused on various aspects of biopolymers with a special emphasis on role of biopolymers in green nanotechnology and agriculture.


2019 ◽  
Vol 22 (3) ◽  
pp. 117-129
Author(s):  
Jana Šimáková ◽  
Nikola Rusková

The aim of the paper is to evaluate the effect of exchange rates on the stock prices of companies in the chemical industry listed on the stock exchanges in the Visegrad Four countries. The empirical analysis was performed from September 2003 to June 2016 on companies from the petrochemical and pharmaceutical industry. The effect of the exchange rate on stock prices is analyzed using Jorion’s approach on monthly data. In contrast to the selected petrochemical companies, the pharmaceutical companies did not use any hedging instruments in the tested period. The effect of the exchange rate on the stock price was proved only in the case of companies from the pharmaceutical industry. This suggests that exchange rate risk could be eliminated by using hedging instruments.


Author(s):  
Obi Peter Adigwe

Background: The role of the pharmaceutical industry in a country such as Nigeria in the provision of safe, high quality and efficacious pharmaceutical products to meet the healthcare need of the populace, cannot be over-emphasized. This study was undertaken to critically look at the issues affecting Medicines’ Security in Nigeria. Methods: A self-completion questionnaire was used for data collection. The questionnaire was administered to participants of an Industry event in September 2017. Data collected were analyzed using Statistical Package for Social Science. Results: A total number of 800 questionnaires were administered to the participants and 529 of the questionnaires were included for analysis. Male participants (58.6%) were more than female participants, all age groups were well represented and more than a third of the respondents had first degree as their minimum qualification. Majority of the respondents (91.3%) indicated that Ministry of Health and its agencies were key to protecting the pharmaceutical sector, while slightly less of that proportion (79.1%) indicated that they patronized Nigeria pharmaceutical products. Almost all the participants (91.7%) supported the need for the local pharmaceutical industry to have access to sustainable funding and other incentives. A similar proportion (89.6%) of the respondents indicated that the local pharmaceutical industry should be prioritized in policy making and implementation. A significant proportion of the study participants (82.3%) indicated that access to medicines in Nigeria is a security issue. Conclusion: To ensure Medicines’ Security and attain medicines self-sufficiency in Nigeria, radical policies must therefore be put in place, together with enabling good business and industrial environment by the government in order to protect, promote and grow the local pharmaceutical industry in Nigeria.


2022 ◽  
Vol 21 (3) ◽  
pp. 303
Author(s):  
Yuli Fitriyani ◽  
Aziz Y ◽  
Rivani R ◽  
Kaltum U ◽  
Sihotang J

The primary purpose of this study is to investigate the role of Total Quality Management (TQM) on business performance in various dimensions. This study proposes a conceptual model that intends to study several research hypotheses. The data were obtained through an online questionnaire, sent to pharmaceutical companies manufactured generic products in Indonesia. The study was conducted based on responses received from 168 valid questionnaires, and it was used partial least squares structural equation modeling (PLS-SEM) to test the hypotheses. Furthermore, we use both of reflective and formative construct with second order/higher order construct in our model of study which is rarely found in the previous study. This research analyzed the dimensions studied in different aspects. TQM variable consists of seven practice, namely management commitment, supplier quality, employee involvement, leadership management, customer orientation, continuous improvement and quality management system, and with respect to business performance, this variable was analyzed through four different perspectives, namely, financial, customer, internal business process and learning & growth. The findings indicate that companies adopt total quality management get improvement in their business performance. Leadership management has greater effect on the successful of TQM practice compared to other TQM dimensions. This study also provides a particular contribution for the companies and expect to be used as feedback related to the execution of their TQM implementation to improve their business performance. Keywords— Balanced Scorecard; Business Performance; Pharmaceutical Industry; Total Quality Management


Author(s):  
Emilia Kaczmarek

Pharmaceutical industry and drugs advertisement is sometimes accused of “creating diseases”. This article assesses and describes the role of that industry in fostering medicalization. First, the notions of medicalization and pharmaceuticalization are defined. Then, the problem of distinguishing between harmful overmedicalization and well-founded medicalization is presented. Next, the phenomenon of disease mongering is explained and illustrated by the case analysis of medicalizing pain and suffering in three contexts: 1) the general idea of medicalizing physical pain, 2) the medicalization of grief, and 3) disease mongering of pseudoaddiction - a condition promoted in order to increase the demand for opioid pain relievers.


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