scholarly journals Electric Field Modeling for Transcranial Magnetic Stimulation and Electroconvulsive Therapy

2019 ◽  
pp. 75-84 ◽  
Author(s):  
Zhi-De Deng ◽  
Conor Liston ◽  
Faith M. Gunning ◽  
Marc J. Dubin ◽  
Egill Axfjörð Fridgeirsson ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Electric Field ◽  
Electroconvulsive Therapy ◽  
Magnetic Stimulation ◽  
Field Modeling

Repetitive transcranial magnetic stimulation as a maintenance therapy strategy after electroconvulsive therapy: a conceptual review

2016 ◽  
Vol Ano 6 ◽  
pp. 6-13
Author(s):  
Mercedes Jurema Oliveira Alves
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Maintenance Therapy ◽  
Electroconvulsive Therapy ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Therapy Strategy

O presente texto faz uma revisão das bases teóricas e dos estudos empíricos disponíveis sobre o uso da estimulação magnética transcraniana de repetição como estratégia terapêutica de manutenção após eletroconvulsoterapia. Há quadros psiquiátricos pouco responsivos a quaisquer tipos de tratamentos, inclusive à eletroconvulsoterapia. O texto mostra que a combinação das técnicas é promissora, porém mais estudos são necessários para se definir as indicações precisas e a eficácia em termos de sustentação da resposta terapêutica.

scholarly journals Repetitive transcranial magnetic stimulation treatment for peripartum depression: systematic review & meta-analysis

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hyune June Lee ◽  
Sung Min Kim ◽  
Ji Yean Kwon
Keyword(s):  
Systematic Review ◽  
Transcranial Magnetic Stimulation ◽  
Side Effects ◽  
Electroconvulsive Therapy ◽  
Effect Size ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Peripartum Depression

Abstract Background Peripartum depression is a common disorder with very high potential hazards for both the patients and their babies. The typical treatment options include antidepressants and electroconvulsive therapy. However, these treatments do not ensure the safety of the fetus. Recently, repetitive transcranial magnetic stimulation has emerged as a promising treatment for neuropathies as well as depression. Nevertheless, many studies excluded pregnant women. This systematic review was conducted to confirm whether repetitive transcranial magnetic stimulation was a suitable treatment option for peripartum depression. Methods We performed a systematic review that followed the PRISMA guidelines. We searched for studies in the MEDLINE, PsycINFO, EMBASE, and Cochrane library databases published until the end of September 2020. Eleven studies were selected for the systematic review, and five studies were selected for quantitative synthesis. Data analysis was conducted using Comprehensive Meta-Analysis 3 software. The effect size was analyzed using the standardized mean difference, and the 95% confidence interval (CI) was determined by the generic inverse variance estimation method. Results The therapeutic effect size of repetitive transcranial magnetic stimulation for peripartum depression was 1.394 (95% CI: 0.944–1.843), and the sensitivity analysis effect size was 1.074 (95% CI: 0.689–1.459), indicating a significant effect. The side effect size of repetitive transcranial magnetic stimulation for peripartum depression was 0.346 (95% CI: 0.214–0.506), a meaningful result. There were no severe side effects to the mothers or fetuses. Conclusions From various perspectives, repetitive transcranial magnetic stimulation can be considered an alternative treatment to treat peripartum depression to avoid exposure of fetuses to drugs and the severe side effects of electroconvulsive therapy. Further research is required to increase confidence in the results.

scholarly journals Proof of concept study to develop a novel connectivity-based electric-field modelling approach for individualized targeting of transcranial magnetic stimulation treatment

2021 ◽  
Author(s):  
Nicholas L. Balderston ◽  
Joanne C. Beer ◽  
Darsol Seok ◽  
Walid Makhoul ◽  
Zhi-De Deng ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Electric Field ◽  
Magnetic Stimulation ◽  
Depression Symptoms ◽  
Single Subject ◽  
Proof Of Concept ◽  
Concept Study ◽  
Field Modelling ◽  
Left Dlpfc ◽  
Modelling Approach

AbstractResting state functional connectivity (rsFC) offers promise for individualizing stimulation targets for transcranial magnetic stimulation (TMS) treatments. However, current targeting approaches do not account for non-focal TMS effects or large-scale connectivity patterns. To overcome these limitations, we propose a novel targeting optimization approach that combines whole-brain rsFC and electric-field (e-field) modelling to identify single-subject, symptom-specific TMS targets. In this proof of concept study, we recruited 91 anxious misery (AM) patients and 25 controls. We measured depression symptoms (MADRS/HAMD) and recorded rsFC. We used a PCA regression to predict symptoms from rsFC and estimate the parameter vector, for input into our e-field augmented model. We modeled 17 left dlPFC and 7 M1 sites using 24 equally spaced coil orientations. We computed single-subject predicted ΔMADRS/HAMD scores for each site/orientation using the e-field augmented model, which comprises a linear combination of the following elementwise products (1) the estimated connectivity/symptom coefficients, (2) a vectorized e-field model for site/orientation, (3) rsFC matrix, scaled by a proportionality constant. In AM patients, our connectivity-based model predicted a significant decrease depression for sites near BA9, but not M1 for coil orientations perpendicular to the cortical gyrus. In control subjects, no site/orientation combination showed a significant predicted change. These results corroborate previous work suggesting the efficacy of left dlPFC stimulation for depression treatment, and predict better outcomes with individualized targeting. They also suggest that our novel connectivity-based e-field modelling approach may effectively identify potential TMS treatment responders and individualize TMS targeting to maximize the therapeutic impact.

scholarly journals Transcranial Magnetic Stimulation Maintenance as a Substitute for Maintenance Electroconvulsive Therapy

2013 ◽  
Vol 29 (2) ◽  
pp. 106-108 ◽  
Author(s):  
Mario A. Cristancho ◽  
Amanda Helmer ◽  
Ryan Connolly ◽  
Pilar Cristancho ◽  
John P. O’Reardon
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Electroconvulsive Therapy ◽  
Magnetic Stimulation

scholarly journals Remission rate of transcranial magnetic stimulation compared with electroconvulsive therapy: a case-control study

2018 ◽  
Vol 72 (7) ◽  
pp. 471-476 ◽  
Author(s):  
Anton Filip Svensson ◽  
Maher Khaldi ◽  
Ingemar Engström ◽  
Katsiaryna Matusevich ◽  
Axel Nordenskjöld
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Electroconvulsive Therapy ◽  
Magnetic Stimulation ◽  
Case Control Study ◽  
Remission Rate ◽  
Case Control ◽  
Control Study
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