Predicting Daily Physical Activity Level for Older Adults Using Wearable Activity Trackers

Background: A decrease in the physical activity level in old age is common, which results in an increase in the number of falls and chronic conditions. Associated with that occurs the decline in motor skills as a result of the deficit in the interaction of cognitive and motor processes. Physical activity level can be associated differently with each motor domains. Objective: We analyzed the relationship between physical activity level and motor aptitude, and to identify which motor domains were most sensitive to detect insufficiently active level in older adults. Methods: Participated in the study 385 elderly people of both sexes. For the evaluation of the subjects were adopted the International Questionnaire on Physical Activity and the Motor Scale for Older Adults. Results: The majority of the elderly were active. In the comparison of motor aptitude between active and insufficiently active (IAC) elders a significant difference was found in the Global Coordination, Balance, Body Scheme and General Motor Aptitude. From the analysis of the area under the curve (AUC), we verified that these domains also were the ones that presented adequate diagnostic accuracy to identify IAC elderly. Besides that active elderly have presented the General Motor Aptitude classified within normality while the IAC below the normal. Conclusion: Our data suggest that IAC older adults present lower motor aptitude than the active elderly, especially in the domains of Global Coordination, Balance, Body Scheme and General Motor Aptitude, and that these domains were sensitive to indicate IAC older adults.

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Nutritional status and physical activity level predict Timed Up and Go performance in Irish older adults

Proceedings of The Nutrition Society ◽

10.1017/s002966512100015x ◽

2021 ◽

Vol 80 (OCE1) ◽

Author(s):

M.L. O'Connell ◽

T. Coppinger ◽

J. Walton ◽

A.L. McCarthy

Keyword(s):

Physical Activity ◽

Older Adults ◽

Nutritional Status ◽

Physical Activity Level ◽

Activity Level ◽

Timed Up And Go

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Effects of Sex and Physical Activity Level on Serum Biomarker-Based Physiological Dysregulation: The Impact to Predict Frailty and Mortality in the Quebec NuAge Cohort

Gerontology ◽

10.1159/000514169 ◽

2021 ◽

pp. 1-14

Author(s):

Ahmed Ghachem ◽

Frédérik Dufour ◽

Tamas Fülöp ◽

Pierrette Gaudreau ◽

Alan A. Cohen

Keyword(s):

Physical Activity ◽

Older Adults ◽

Kidney Function ◽

Oxygen Transport ◽

Physical Activity Level ◽

Rate Of Change ◽

Activity Level ◽

Men And Women ◽

Physiological Dysregulation ◽

The Impact

Background: Age-related changes in biological processes such as physiological dysregulation (the progressive loss of homeostatic capacity) vary considerably among older adults and may influence health profiles in late life. These differences could be related, at least in part, to the impact of intrinsic and extrinsic factors such as sex and physical activity level (PAL). Objectives: The objectives of this study were (1) to assess the magnitude and rate of changes in physiological dysregulation in men and women according to PAL and (2) to determine whether/how sex and PAL mediate the apparent influence of physiological dysregulation on health outcomes (frailty and mortality). Methods: We used data on 1,754 community-dwelling older adults (age = 74.4 ± 4.2 years; women = 52.4%) of the Quebec NuAge cohort study. Physiological dysregulation was calculated based on Mahalanobis distance of 31 biomarkers regrouped into 5 systems: oxygen transport, liver/kidney function, leukopoiesis, micronutrients, and lipids. Results: As expected, mean physiological dysregulation significantly increased with age while PAL decreased. For the same age and PAL, men showed higher levels of physiological dysregulation globally in 3 systems: oxygen transport, liver/kidney function, and leukopoiesis. Men also showed faster global physiological dysregulation in the liver/kidney and leukopoiesis systems. Overall, high PAL was associated with lower level and slower rate of change of physiological dysregulation. Finally, while mortality and frailty risk significantly increased with physiological dysregulation, there was no evidence for differences in these effects between sexes and PAL. Conclusion: Our results showed that both sex and PAL have a significant effect on physiological dysregulation levels and rates of change. Also, although a higher PAL was associated with lower level and slower rate of change of physiological dysregulation, there was no evidence that PAL attenuates the effect of physiological dysregulation on subsequent declines in health at the end of life. Substantial work remains to understand how modifiable behaviors impact the relationship between physiological dysregulation, frailty, and mortality in men and women.

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Genetic analysis of daily physical activity using a mouse chromosome substitution strain

Physiological Genomics ◽

10.1152/physiolgenomics.00066.2009 ◽

2009 ◽

Vol 39 (1) ◽

pp. 47-55 ◽

Cited By ~ 16

Author(s):

He S. Yang ◽

Martha H. Vitaterna ◽

Aaron D. Laposky ◽

Kazuhiro Shimomura ◽

Fred W. Turek

Keyword(s):

Physical Activity ◽

Physical Activity Level ◽

Wheel Running ◽

Daily Physical Activity ◽

Activity Level ◽

Constant Darkness ◽

Circadian Period ◽

Chromosome 13 ◽

Running Activity ◽

Wheel Running Activity

There is considerable evidence for a genetic basis underlying individual differences in spontaneous physical activity in humans and animals. Previous publications indicate that the physical activity level and pattern vary among inbred strains of mice and identified a genomic region on chromosome 13 as quantitative trait loci (QTL) for physical activity. To confirm and further characterize the role of chromosome 13 in regulating daily physical activity level and pattern, we conducted a comprehensive phenotypic study in the chromosome 13 substitution strain (CSS-13) in which the individual chromosome 13 from the A/J strain was substituted into an otherwise complete C57BL/6J (B6) genome. The B6 and A/J parental strains exhibited pronounced differences in daily physical activity, sleep-wake structure, circadian period and body weight. Here we report that a single A/J chromosome 13 in the context of a B6 genetic background conferred a profound reduction in both total cage activity and wheel-running activity under a 14:10-h light-dark cycle, as well as in constant darkness, compared with B6 controls. Additionally, CSS-13 mice differed from B6 controls in the diurnal distribution of activity and the day-to-day variability in activity onset. We further performed a linkage analysis and mapped a significant QTL on chromosome 13 regulating the daily wheel running activity level in mice. Taken together, our findings indicate a QTL on chromosome 13 with dramatic and specific effects on daily voluntary physical activity, but not on circadian period, sleep, or other aspects of activity that are different between B6 and A/J strains.

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