An Agent-Based Study of the Impact of Sensitization on the Spread of Covid 19 in Burkina Faso

Author(s):  
Eric Youl ◽  
Sadouanouan Malo ◽  
Stanislas Ouaro
Keyword(s):  
Pharmaceutics ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 996
Author(s):  
Niels Lasse Martin ◽  
Ann Kathrin Schomberg ◽  
Jan Henrik Finke ◽  
Tim Gyung-min Abraham ◽  
Arno Kwade ◽  
...  

In pharmaceutical manufacturing, the utmost aim is reliably producing high quality products. Simulation approaches allow virtual experiments of processes in the planning phase and the implementation of digital twins in operation. The industrial processing of active pharmaceutical ingredients (APIs) into tablets requires the combination of discrete and continuous sub-processes with complex interdependencies regarding the material structures and characteristics. The API and excipients are mixed, granulated if required, and subsequently tableted. Thereby, the structure as well as the properties of the intermediate and final product are influenced by the raw materials, the parametrized processes and environmental conditions, which are subject to certain fluctuations. In this study, for the first time, an agent-based simulation model is presented, which enables the prediction, tracking, and tracing of resulting structures and properties of the intermediates of an industrial tableting process. Therefore, the methodology for the identification and development of product and process agents in an agent-based simulation is shown. Implemented physical models describe the impact of process parameters on material structures. The tablet production with a pilot scale rotary press is experimentally characterized to provide calibration and validation data. Finally, the simulation results, predicting the final structures, are compared to the experimental data.


Safety ◽  
2021 ◽  
Vol 7 (2) ◽  
pp. 47
Author(s):  
Wattana Chanthakhot ◽  
Kasin Ransikarbum

Emergency events in the industrial sector have been increasingly reported during the past decade. However, studies that focus on emergency evacuation to improve industrial safety are still scarce. Existing evacuation-related studies also lack a perspective of fire assembly point’s analysis. In this research, location of assembly points is analyzed using the multi-criteria decision analysis (MCDA) technique based on the integrated information entropy weight (IEW) and techniques for order preference by similarity to ideal solution (TOPSIS) to support the fire evacuation plan. Next, we propose a novel simulation model that integrates fire dynamics simulation coupled with agent-based evacuation simulation to evaluate the impact of smoke and visibility from fire on evacuee behavior. Factors related to agent and building characteristics are examined for fire perception of evacuees, evacuees with physical disabilities, escape door width, fire location, and occupancy density. Then, the proposed model is applied to a case study of a home appliance factory in Chachoengsao, Thailand. Finally, results for the total evacuation time and the number of remaining occupants are statistically examined to suggest proper evacuation planning.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Jonatan Almagor ◽  
Stefano Picascia

AbstractA contact-tracing strategy has been deemed necessary to contain the spread of COVID-19 following the relaxation of lockdown measures. Using an agent-based model, we explore one of the technology-based strategies proposed, a contact-tracing smartphone app. The model simulates the spread of COVID-19 in a population of agents on an urban scale. Agents are heterogeneous in their characteristics and are linked in a multi-layered network representing the social structure—including households, friendships, employment and schools. We explore the interplay of various adoption rates of the contact-tracing app, different levels of testing capacity, and behavioural factors to assess the impact on the epidemic. Results suggest that a contact tracing app can contribute substantially to reducing infection rates in the population when accompanied by a sufficient testing capacity or when the testing policy prioritises symptomatic cases. As user rate increases, prevalence of infection decreases. With that, when symptomatic cases are not prioritised for testing, a high rate of app users can generate an extensive increase in the demand for testing, which, if not met with adequate supply, may render the app counterproductive. This points to the crucial role of an efficient testing policy and the necessity to upscale testing capacity.


2020 ◽  
Vol 5 (9) ◽  
pp. e002879
Author(s):  
Thomas Druetz ◽  
Lalique Browne ◽  
Frank Bicaba ◽  
Matthew Ian Mitchell ◽  
Abel Bicaba

IntroductionMost of the literature on terrorist attacks’ health impacts has focused on direct victims rather than on distal consequences in the overall population. There is limited knowledge on how terrorist attacks can be detrimental to access to healthcare services. The objective of this study is to assess the impact of terrorist attacks on the utilisation of maternal healthcare services by examining the case of Burkina Faso.MethodsThis longitudinal quasi-experimental study uses multiple interrupted time series analysis. Utilisation of healthcare services data was extracted from the National Health Information System in Burkina Faso. Data span the period of January 2013–December 2018 and include all public primary healthcare centres and district hospitals. Terrorist attack data were extracted from the Armed Conflict Location and Event Data project. Negative binomial regression models were fitted with fixed effects to isolate the immediate and long-term effects of terrorist attacks on three outcomes (antenatal care visits, of facility deliveries and of cesarean sections).ResultsDuring the next month of an attack, the incidence of assisted deliveries in healthcare facilities is significantly reduced by 3.8% (95% CI 1.3 to 6.3). Multiple attacks have immediate effects more pronounced than single attacks. Longitudinal analysis show that the incremental number of terrorist attacks is associated with a decrease of the three outcomes. For every additional attack in a commune, the incidence of cesarean sections is reduced by 7.7% (95% CI 4.7 to 10.7) while, for assisted deliveries, it is reduced by 2.5% (95% CI 1.9 to 3.1) and, for antenatal care visits, by 1.8% (95% CI 1.2 to 2.5).ConclusionTerrorist attacks constitute a new barrier to access of maternal healthcare in Burkina Faso. The exponential increase in terrorist activities in West Africa is expected to have negative effects on maternal health in the entire region.


Author(s):  
Ardeshir Raihanian Mashhadi ◽  
Behzad Esmaeilian ◽  
Sara Behdad

As electronic waste (e-waste) becomes one of the fastest growing environmental concerns, remanufacturing is considered as a promising solution. However, the profitability of take back systems is hampered by several factors including the lack of information on the quantity and timing of to-be-returned used products to a remanufacturing facility. Product design features, consumers’ awareness of recycling opportunities, socio-demographic information, peer pressure, and the tendency of customer to keep used items in storage are among contributing factors in increasing uncertainties in the waste stream. Predicting customer choice decisions on returning back used products, including both the time in which the customer will stop using the product and the end-of-use decisions (e.g. storage, resell, through away, and return to the waste stream) could help manufacturers have a better estimation of the return trend. The objective of this paper is to develop an Agent Based Simulation (ABS) model integrated with Discrete Choice Analysis (DCA) technique to predict consumer decisions on the End-of-Use (EOU) products. The proposed simulation tool aims at investigating the impact of design features, interaction among individual consumers and socio-demographic characteristics of end users on the number of returns. A numerical example of cellphone take-back system has been provided to show the application of the model.


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