Individualised Treatment

2014 ◽  
pp. 277-283
Author(s):  
Birger Henning Endreseth
Keyword(s):  
Individualised Treatment

A care service model for cost effective and structured individualised treatment choice for GH replacement therapy

2015 ◽  
Author(s):  
Sofia Llahana ◽  
Awal Mumuni ◽  
Marta Osz ◽  
Mawgen Baber ◽  
Stephanie Baldeweg ◽  
...  
Keyword(s):  
Replacement Therapy ◽  
Care Service ◽  
Cost Effective ◽  
Treatment Choice ◽  
Service Model ◽  
Gh Replacement ◽  
Individualised Treatment

An individualised treatment algorithm for tumour stage 1 glottic squamous cell carcinoma

2013 ◽  
Vol 127 (11) ◽  
pp. 1127-1133 ◽  
Author(s):  
U Aydil ◽  
M Akmansu ◽  
Y Kizil ◽  
Ö Yazici ◽  
S Üstün ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Survival Rates ◽  
Treatment Algorithm ◽  
Tumour Stage ◽  
Treatment Groups ◽  
Laryngeal Preservation ◽  
Stage 1 ◽  
Individualised Treatment

AbstractObjective:To report and discuss the outcome of a treatment algorithm for patients with tumour stage 1 glottic squamous cell carcinoma.Method:A retrospective outcome analysis study was performed using data from a tertiary referral centre.Results:Sixty-nine patients were treated with radiotherapy and 26 with surgery, in accordance with the treatment algorithm. Five-year overall survival rates were the same for both treatment groups (92 per cent). Five-year disease-specific survival rates were 100 per cent for surgery, 98 per cent for radiotherapy and 99 per cent overall. The overall 5-year laryngeal preservation rate was 89.1 per cent, being 95.7 per cent for surgery patients and 86.7 per cent for radiotherapy patients (p = 0.502). There was no significant association between laryngeal preservation rates and age (p = 0.779), anterior commissure involvement (p = 0.081), tumour stage (1a or 1b) (p = 0.266) or treatment modality (surgery or radiotherapy; p = 0.220). There was no significant difference in local recurrence rates between the two treatment groups (19.3 per cent for radiotherapy vs 10.0 per cent for surgery; p = 0.220). The overall 5-year regional recurrence rate was 1.2 per cent.Conclusion:Tumour stage 1 glottic carcinoma can be managed with different treatment modalities, following an individualised treatment algorithm, with results comparable to published outcomes.

scholarly journals Graves' disease: pathophysiological aspects and considerations about using the chemometric analysis in the study of the disease

Folia Medica ◽  
2021 ◽  
Vol 63 (4) ◽  
pp. 467-474
Author(s):  
Pavlina M. Koseva ◽  
Zdravko A. Kamenov ◽  
Mariana M. Nikolova ◽  
Pavlina A. Andreeva-Gateva
Keyword(s):  
Treatment Strategies ◽  
Well Being ◽  
Chemometric Analysis ◽  
Observation Group ◽  
Public Concern ◽  
High Prevalence ◽  
Societal Problem ◽  
System Disorder ◽  
Individualised Treatment

Graves’ disease is an immune system disorder that results in the overproduction of thyroid hormones (hyperthyroidism). Thyroid disorders are a societal problem of great public concern because of their high prevalence. This problem can affect the well-being and quality of life of patients. The predisposing factors leading to this disease are not yet fully established and are likely to be interconnected in a complex way.  Chemometric analysis allows for the detection of specific relationships between the medical parameter measurements obtained from the patients in an observation group, and the identification of patterns of similarity between these patients. It is not commonly used in clinical trials; however, it can provide reliable information which may help in creating more successful, individualised treatment strategies for established groups (patterns) of patients. The aim of this review is to summarize the latest knowledge about the risk factors for Graves’ disease and considerations about using the chemometric analysis in the study of the disease.

The use of MRI and micro RNA in the individualised treatment of rectal cancer

2020 ◽  
Vol 75 ◽  
pp. e3
Author(s):  
Donald Courtney ◽  
Peter McCarthy ◽  
Brian Moloney ◽  
John Gaffney ◽  
Nicola Miller ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Micro Rna ◽  
Individualised Treatment

scholarly journals Post-traumatic bronchobiliary fistula

2019 ◽  
Vol 12 (4) ◽  
pp. e228294 ◽  
Author(s):  
Niladri Banerjee ◽  
Amulya Rattan ◽  
Pratyusha Priyadarshini ◽  
Subodh Kumar
Keyword(s):  
Early Diagnosis ◽  
Surgical Management ◽  
Gold Standard ◽  
Complete Recovery ◽  
Rare Entity ◽  
Bronchobiliary Fistula ◽  
Confirmatory Tests ◽  
Post Traumatic ◽  
Torso Trauma ◽  
Individualised Treatment

Post-traumatic bronchobiliary fistula (BBF) is a rare entity, with only a few cases reported worldwide. Bilioptysis is pathognomonic of the condition, however, bronchoscopy and bronchoalveolar lavage along with CT are used for confirmation. We describe this condition in a young woman who presented to us with bilioptysis following a laparotomy for blunt torso trauma. Diagnosis was made of BBF, followed by surgical management and complete recovery. We emphasise the signs of early diagnosis, confirmatory tests, individualised treatment and advocate surgical management as the gold standard of treatment.

scholarly journals A Personalised Dietary Approach—A Way Forward to Manage Nutrient Deficiency, Effects of the Western Diet, and Food Intolerances in Inflammatory Bowel Disease

Nutrients ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1532 ◽  
Author(s):  
Bobbi B Laing ◽  
Anecita Gigi Lim ◽  
Lynnette R Ferguson
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Nutrient Deficiency ◽  
Pharmaceutical Products ◽  
Western Diet ◽  
Nutritional Deficiencies ◽  
Nutrient Interactions ◽  
Beneficial Effects ◽  
Inflammatory Bowel ◽  
Individualised Treatment

This review discusses the personalised dietary approach with respect to inflammatory bowel disease (IBD). It identifies gene–nutrient interactions associated with the nutritional deficiencies that people with IBD commonly experience, and the role of the Western diet in influencing these. It also discusses food intolerances and how particular genotypes can affect these. It is well established that with respect to food there is no “one size fits all” diet for those with IBD. Gene–nutrient interactions may help explain this variability in response to food that is associated with IBD. Nutrigenomic research, which examines the effects of food and its constituents on gene expression, shows that—like a number of pharmaceutical products—food can have beneficial effects or have adverse (side) effects depending on a person’s genotype. Pharmacogenetic research is identifying gene variants with adverse reactions to drugs, and this is modifying clinical practice and allowing individualised treatment. Nutrigenomic research could enable individualised treatment in persons with IBD and enable more accurate tailoring of food intake, to avoid exacerbating malnutrition and to counter some of the adverse effects of the Western diet. It may also help to establish the dietary pattern that is most protective against IBD.

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