The Excluded Patients of the BLUE-Protocol: Who Are They? Did Their Exclusion Limit Its Value?

2016 ◽  
pp. 167-169
Author(s):  
Daniel A. Lichtenstein
Keyword(s):  
Exclusion Limit

The conjugation process in the jelly fungus Sirobasidium magnum

1981 ◽  
Vol 59 (5) ◽  
pp. 929-938 ◽  
Author(s):  
T. W. Flegel
Keyword(s):  
Cell Division ◽  
Cyclic Nucleotides ◽  
Tube Formation ◽  
Cell Division Cycle ◽  
Yeast Cells ◽  
Exclusion Limit ◽  
Morphological Abnormalities ◽  
Secondary Messengers ◽  
Dialysis Membranes ◽  
Conjugation Process

The formation of conjugation tubes in yeast cells of the jelly fungus Sirobasidium magnum (Basidiomycotina) was shown to be mediated by diffusible pheromones which passed through dialysis membranes of 12 000 to 14 000 daltons molecular exclusion limit. The yeast cells were responsive to pheromone only in G1 of the cell division cycle. Although caffeine induced morphological abnormalities in the yeast cells and although conjugation tube formation was catabolically repressed by glucose, evidence for the involvement of cyclic nucleotides as secondary messengers in conjugation tube induction was negative. There was some evidence for the presence of a conjugation inhibitor(s).

scholarly journals First results of the CAST-RADES haloscope search for axions at 34.67 μeV

2021 ◽  
Vol 2021 (10) ◽  
Author(s):  
A. Álvarez Melcón ◽  
S. Arguedas Cuendis ◽  
J. Baier ◽  
K. Barth ◽  
H. Bräuninger ◽  
...  
Keyword(s):  
Dark Matter ◽  
Mass Range ◽  
Dark Matter Candidate ◽  
Coupling Constant ◽  
Exclusion Limit ◽  
Dipole Magnet ◽  
Resonant Cavities ◽  
First Results ◽  
First Time ◽  
Photon Coupling

Abstract We present results of the Relic Axion Dark-Matter Exploratory Setup (RADES), a detector which is part of the CERN Axion Solar Telescope (CAST), searching for axion dark matter in the 34.67 μeV mass range. A radio frequency cavity consisting of 5 sub-cavities coupled by inductive irises took physics data inside the CAST dipole magnet for the first time using this filter-like haloscope geometry. An exclusion limit with a 95% credibility level on the axion-photon coupling constant of gaγ ≳ 4 × 10−13 GeV−1 over a mass range of 34.6738 μeV < ma< 34.6771 μeV is set. This constitutes a significant improvement over the current strongest limit set by CAST at this mass and is at the same time one of the most sensitive direct searches for an axion dark matter candidate above the mass of 25 μeV. The results also demonstrate the feasibility of exploring a wider mass range around the value probed by CAST-RADES in this work using similar coherent resonant cavities.

scholarly journals Reinterpreting the ATLAS bounds on heavy neutral leptons in a realistic neutrino oscillation model

2021 ◽  
Vol 2021 (12) ◽  
Author(s):  
J.-L. Tastet ◽  
O. Ruchayskiy ◽  
I. Timiryasov
Keyword(s):  
Neutrino Oscillation ◽  
Neutrino Oscillations ◽  
Realistic Model ◽  
Model Parameters ◽  
Exclusion Limit ◽  
Final State ◽  
Mixing Angle ◽  
Mixing Angles ◽  
Oscillation Model ◽  
Free Parameters

Abstract Heavy neutral leptons (HNLs) are hypothetical particles, motivated in the first place by their ability to explain neutrino oscillations. Experimental searches for HNLs are typically conducted under the assumption of a single HNL mixing with a single neutrino flavor. However, the resulting exclusion limits may not directly constrain the corresponding mixing angles in realistic HNL models — those which can explain neutrino oscillations. The reinterpretation of the results of these experimental searches turns out to be a non-trivial task, that requires significant knowledge of the details of the experiment. In this work, we perform a reinterpretation of the latest ATLAS search for HNLs decaying promptly to a tri-lepton final state. We show that in a realistic model with two HNLs, the actual limits can vary by several orders of magnitude depending on the free parameters of the model. Marginalizing over the unknown model parameters leads to an exclusion limit on the total mixing angle which can be up to 3 orders of magnitude weaker than the limits reported in ref. [1]. This demonstrates that the reinterpretation of results from experimental searches is a necessary step to obtain meaningful limits on realistic models. We detail a few steps that can be taken by experimental collaborations in order to simplify the reuse of their results.

Identification of a developmental transition in plasmodesmatal function during embryogenesis in Arabidopsis thaliana

Development ◽  
2002 ◽  
Vol 129 (5) ◽  
pp. 1261-1272 ◽  
Author(s):  
Insoon Kim ◽  
Frederick D. Hempel ◽  
Kyle Sha ◽  
Jennifer Pfluger ◽  
Patricia C. Zambryski
Keyword(s):  
Size Exclusion ◽  
Nutrient Transfer ◽  
Intercellular Signaling ◽  
Wild Type ◽  
Exclusion Limit ◽  
Fluorescent Tracer ◽  
Cell Transport ◽  
Developmental Transition ◽  
Size Exclusion Limit ◽  
Chromosome I

Plasmodesmata provide routes for communication and nutrient transfer between plant cells by interconnecting the cytoplasm of adjacent cells. A simple fluorescent tracer loading assay was developed to monitor patterns of cell-to-cell transport via plasmodesmata specifically during embryogenesis. A developmental transition in plasmodesmatal size exclusion limit was found to occur at the torpedo stage of embryogenesis in Arabidopsis; at this time, plasmodesmata are down-regulated, allowing transport of small (approx. 0.5 kDa) but not large (approx. 10 kDa) tracers. This assay system was used to screen for embryo-defective mutants, designated increased size exclusion limit of plasmodesmata(ise), that maintain dilated plasmodesmata at the torpedo stage. The morphology of ise1 and ise2 mutants discussed here resembled that of the wild-type during embryo development, although the rate of their embryogenesis was slower. The ISE1 gene was mapped to position 13 cM on chromosome I using PCR-based biallelic markers. ise2 was found to be allelic to the previously characterized mutant emb25 which maps to position 100 cM on chromosome I. The results presented have implications for intercellular signaling pathways that regulate embryonic development, and furthermore represent the first attempt to screen directly for mutants of Arabidopsis with altered size exclusion limit of plasmodesmata.

The chloroplastic DEVH-box RNA helicase INCREASED SIZE EXCLUSION LIMIT 2 involved in plasmodesmata regulation is required for group II intron splicing

2015 ◽  
Vol 39 (1) ◽  
pp. 165-173 ◽  
Author(s):  
Nicolas Carlotto ◽  
Sonia Wirth ◽  
Nicolas Furman ◽  
Nazarena Ferreyra Solari ◽  
Federico Ariel ◽  
...  
Keyword(s):  
Group Ii Intron ◽  
Rna Helicase ◽  
Size Exclusion ◽  
Intron Splicing ◽  
Exclusion Limit ◽  
Size Exclusion Limit ◽  
Group Ii
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