Spotlight on Minimal Residual Disease (MRD): Impact of MRD on HSCT Outcomes for Pediatric Leukemia

Weiterentwicklungen in der Molekulardiagnostik ermöglichen zuverlässigere Aussagen zur Differenzialdiagnostik maligner Erkrankungen. Sie sind Meilensteine für eine individualisierte Therapie. Darüber hinaus zeigt sich ihre zunehmende Bedeutung für prognostische Einschätzungen. Die Kontrolle der minimalen Resterkrankung (Minimal Residual Disease; MRD) rückt zunehmend in den Fokus, auch wenn noch viele Fragen zu klären sind.

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A mathematical approach to data evaluation with focus on prediction of minimal residual disease in pediatric ALL

Klinische Pädiatrie ◽

10.1055/s-0032-1310472 ◽

2012 ◽

Vol 224 (03) ◽

Author(s):

A Torge ◽

M Zimmermann ◽

A Möricke ◽

R Köhler ◽

A Schrauder ◽

...

Keyword(s):

Minimal Residual Disease ◽

Residual Disease ◽

Data Evaluation ◽

Mathematical Approach ◽

Pediatric All ◽

Minimal Residual

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Improving Diagnostic Methods for Minimal Residual Disease Detection (MRD) in Childhood Acute Lymphoblastic Leukemia (ALL)

Klinische Pädiatrie ◽

10.1055/s-0034-1374837 ◽

2014 ◽

Vol 226 (03) ◽

Author(s):

A Szymansky ◽

S Groeneveld-Krentz ◽

J Hof ◽

R Kirschner-Schwabe ◽

C Eckert

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Minimal Residual Disease ◽

Residual Disease ◽

Lymphoblastic Leukemia ◽

Diagnostic Methods ◽

Childhood Acute Lymphoblastic Leukemia ◽

Disease Detection ◽

Minimal Residual Disease Detection ◽

Minimal Residual

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02 / Assessment of a sensitive and specific method to detect Ewing sarcoma minimal residual disease in testicular and ovarian tissue by RT-qPCR

10.26226/morressier.5af300b1738ab10027aa97db ◽

2018 ◽

Author(s):

Laure Chaput ◽

Florence Brugnon

Keyword(s):

Minimal Residual Disease ◽

Ewing Sarcoma ◽

Residual Disease ◽

Ovarian Tissue ◽

Specific Method ◽

Minimal Residual

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A Study of Daratumumab Plus Lenalidomide Versus Lenalidomide Alone as Maintenance Treatment in Participants With Newly Diagnosed Multiple Myeloma Who Are Minimal Residual Disease Positive After Frontline Autologous Stem Cell Transplant

Case Medical Research ◽

10.31525/ct1-nct03901963 ◽

2019 ◽

Author(s):

Keyword(s):

Multiple Myeloma ◽

Stem Cell ◽

Minimal Residual Disease ◽

Maintenance Treatment ◽

Stem Cell Transplant ◽

Residual Disease ◽

Autologous Stem Cell Transplant ◽

Cell Transplant ◽

Newly Diagnosed ◽

Minimal Residual

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Next Generation Sequencing（NGS）Monitors Minimal Residual Disease（MRD）in Allo-PBSCT Patients

Case Medical Research ◽

10.31525/ct1-nct04126967 ◽

2019 ◽

Author(s):

Keyword(s):

Next Generation Sequencing ◽

Minimal Residual Disease ◽

Residual Disease ◽

Next Generation ◽

Next Generation Sequencing Ngs ◽

Generation Sequencing ◽

Minimal Residual

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Faculty Opinions recommendation of Low platelet counts after induction therapy for childhood acute lymphoblastic leukemia are strongly associated with poor early response to treatment as measured by minimal residual disease and are prognostic for treatment outcome.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.14267017.15779136 ◽

2012 ◽

Author(s):

Jan Starý ◽

Jana Volejnikova

Keyword(s):

Treatment Outcome ◽

Acute Lymphoblastic Leukemia ◽

Minimal Residual Disease ◽

Induction Therapy ◽

Residual Disease ◽

Lymphoblastic Leukemia ◽

Early Response ◽

Childhood Acute Lymphoblastic Leukemia ◽

Response To Treatment ◽

Minimal Residual

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Faculty Opinions recommendation of Clinical significance of low levels of minimal residual disease at the end of remission induction therapy in childhood acute lymphoblastic leukemia.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.3974956.3733054 ◽

2010 ◽

Author(s):

Sheila Weitzman ◽

Sumit Gupta

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Minimal Residual Disease ◽

Clinical Significance ◽

Induction Therapy ◽

Residual Disease ◽

Lymphoblastic Leukemia ◽

Childhood Acute Lymphoblastic Leukemia ◽

Remission Induction ◽

Low Levels ◽

Minimal Residual

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