Fully Implantable Blood Pressure System: Implantation Experiences

Author(s):  
U. Urban ◽  
R. Ballan ◽  
H. Fassbender ◽  
P. Fuerst ◽  
T. Goettsche ◽  
...  
Author(s):  
Enrique Alvarez Vazquez ◽  
Daniel Ewert ◽  
Dave Jorgenson ◽  
Michael Sand

Abstract This study describes a non-invasive medical device capable of measuring arterial blood pressure (BP) with a combination of inflationary and deflationary procedures. The device uses the pressure cuff pressure signal, arterial skin-surface acoustics, and photoplethysmography (PPG) to make a sensor-fusion estimation of blood pressure readings. We developed an apparatus composed of 1) a modified off-the-shelf oscillometric blood pressure system, 2) a contact microphone with an amplifier, 3) and high-sensitivity pulse oximeter, and its control electronics.


2000 ◽  
Vol 84 (S1) ◽  
pp. 119-125 ◽  
Author(s):  
Susan M. Groziak ◽  
G. D. Miller

High blood pressure is a significant public health problem worldwide which is associated with increased risk of cardiovascular disease, stroke, and renal disease. The development of this disease is influenced by genetic and environmental factors. The results of many studies have linked increased consumption of milk and milk products with lower blood pressure and reduced risk of hypertension. The intake of several minerals found in milk has been demonstrated to have an inverse relationship with blood pressure. Peptides formed during the digestion of milk proteins have also been demonstrated to have a blood pressure lowering effect. Other components in milk that have been examined for their effects on blood pressure have been less promising. More recent data indicate that a dietary pattern that is low in fat, with fruits, vegetables, and low fat dairy products can significantly reduce blood pressure and lower risk of developing high blood pressure.


1985 ◽  
Vol 3 (4) ◽  
pp. 337-342 ◽  
Author(s):  
Gerard M. London ◽  
Michael E. Safar ◽  
Anne L. Safar ◽  
Alain Ch. Simon

2018 ◽  
Vol 8 (2) ◽  
pp. 248-257
Author(s):  
Ana Lucia Barbosa Goes ◽  
Davi Mota De Jesus ◽  
Tiago Bastos Silva ◽  
Vinícius Cardoso Lago ◽  
Luis Agnaldo Pereira De Souza ◽  
...  

INTRODUCTION: blood pressure System (SNS) has been considered as the ultimate integrator of the systems’ physiology on Blood Pressure (BP) control. Posture is also regulated by SNS. Systems which regulate BP also act on postural control. OBJECTIVE: To test the hypothesis of an association between postural misalignments (PM) and BP fall in hypertensive individuals. METHODS: Exploratory study using a sample of 40 hypertensive individuals, who regularly use antihypertensive drugs. All of them underwent Ambulatory Blood Pressure Monitoring (ABPM) and posture assessment, through Postural Assessment Software (PAS). To test association between posture angles and BP variables, the student’s t-test and Mann-Whitney tests were used, at a 5% level of significance. This study is registered at clinical trials, under the number NCT02401516. RESULTS: For Systolic Blood Pressure (SBP), anterior trunk shift presented smaller awake/asleep variation (14.7%vs25.3%, p=0.01), and flexing ankle for higher BP loads: 21.9%vs7.8% for total load (p=0.02), 21.8%vs9% for load during the period awake (p=0.04) and 21.9%vs7.9% for load during the period asleep (p=0.02). For Diastolic Blood Pressure (DBP), posterior trunk shift presented higher pressure load (24.0%vs16.2%, p=0.04), and anterior trunk shift presented smaller awake/asleep variation (14.4%vs25.5%, p=0.01) and flexing hip presented higher BP load (29.4%vs18.3%, p=0.02). From posture scores, the PM presented smaller awake/asleep variation for SBP (13.7%vs22.8%, p=0.03) and DBP (11.5%vs23.5%, p=0.01). CONCLUSION: PM can be associated with pressure fall. Three or more alterations in posture angles are associated with smaller awake/asleep BP variation.


Author(s):  
Afrillia Nuryanti Garmana ◽  
Elin Yulinah Sukandar ◽  
Irda Fidrianny

 Objective: The aims of this study were to prove the antihypertensive effect of Anredera cordifolia (Madeira vine) in dexamethasone-induced hypertensive rat and to determine the release of nitric oxide (NO).Methods: The rat’s blood pressure was measured by CODA® tail-cuff blood pressure system. A hypertensive rat model was developed on day 7 after administration of dexamethasone injection 0.5 mg/kg body weight (bw). NO levels were measured by spectrophotometry at a wavelength of 546 nm after reacting the serum sample with Griess reagent.Results: Ethanol extract of Madeira vine (EEMV), ethyl acetate fraction (EF), and water fraction (WF) could reduce systolic blood pressure at day 14 with a diastolic blood pressure (DBP) reduction of 26.8, 34.1, and 40.5 mmHg, respectively. DBP began to decrease from day 8 in the EEMV group with a DBP reduction of 24.1 mmHg. In the HF, EF, and WF groups, decreasing in DBP occurred on day 14 which were 22.0, 24.5, and 35.4 mmHg, respectively. NO level in rat serum was increased significantly at 90 min after administration of EEMV 100 mg/kg bw and WF 40.73 mg/kg bw. Increasing in NO levels due to EF with a dose of 1.66 mg/kg bw was not significantly different to control group.Conclusion: Ethanol extract of A. cordifolia had the antihypertensive effect in dexamethasone-induced hypertensive rats, so does its WF and EF. The mechanism of ethanol extract of Madeira vine leaves and its WF most likely due to vasodilation effect through NO-pathway, whereas EF could have other mechanism(s) of action. 


2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Manuela Ciocoiu ◽  
Laurentiu Badescu ◽  
Anca Miron ◽  
Magda Badescu

The aim of this study is to characterize the content ofAronia melanocarpaElliott (black chokeberry) extract and also to estimate the influence of polyphenolic compounds contained in chokeberries on oxidative stress, on an L-NAME-induced experimental model of arterial hypertension. The rat blood pressure values were recorded using a CODA Noninvasive Blood Pressure System. HPLC/DAD coupled with ElectroSpray Ionization-Mass Spectrometry allowed identification of five phenolic compounds in berries ethanolic extract as follows: chlorogenic acid, kuromanin, rutin, hyperoside, and quercetin. The serous activity of glutathione-peroxidase (GSH-Px) has significantly lower values in the hypertensive (AHT) group as compared to the group protected by polyphenols (AHT + P). The total antioxidant capacity (TAC) values are lower in the AHT group and they are significantly higher in the AHT + P group. All the measured blood pressure components revealed a biostatistically significant blood pressure drop between the AHT group and the AHT + P group. The results reveal the normalization of the reduced glutathion (GSH) concentration as well as a considerable reduction in the malondialdehyde (MDA) serum concentration in the AHT + P group. Ethanolic extract of black chokeberry fruits not only has a potential value as a prophylactic agent but also may function as a nutritional supplement in the management of arterial hypertension.


1978 ◽  
Vol 12 ◽  
pp. 524-524
Author(s):  
Leonard L Fox ◽  
Dale L Phelps

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