Brugada Sign: What Is the Prevalence in an Apparently Healthy Population?

2002 ◽  
pp. 198-205
Author(s):  
A. Nava ◽  
B. Bauce ◽  
S. Cannas ◽  
A. Rampazzo ◽  
B. Martini
Keyword(s):  
Healthy Population ◽  
Apparently Healthy

Development of Mobile Application for Assessment of Basic Echocardiographic Parameters in Apparently Healthy Population

2021 ◽  
Author(s):  
Irina V. Pospelova ◽  
Dmitry S. Bragin ◽  
Irina V. Cherepanova ◽  
Victoriya N. Serebryakova ◽  
Alexander A. Sokolov ◽  
...  
Keyword(s):  
Mobile Application ◽  
Healthy Population ◽  
Echocardiographic Parameters ◽  
Apparently Healthy

U-Shaped Association Between the Triglycerides-Glucose index and the Risk of Incident Diabetes in Apparently Healthy Population: A Population-based Cohort Study

2020 ◽  
Author(s):  
Xiuping Xuan ◽  
Masahide Hamaguchi ◽  
Qiuli Cao ◽  
Okamura Takuro ◽  
Yoshitaka Hashimoto ◽  
...  
Keyword(s):  
Linear Regression ◽  
Regression Model ◽  
Linear Regression Model ◽  
Piecewise Linear ◽  
Incident Diabetes ◽  
Smoothing Function ◽  
Healthy Population ◽  
Piecewise Linear Regression ◽  
Tyg Index ◽  
Apparently Healthy

Abstract Background Although the triglycerides-glucose (TyG) index was thought to be a practical predictor of incident diabetes, the association between them has not been well characterized. The study aimed to further examine the association between the TyG index and incident diabetes in Japanese adults. Methods The cases were extracted of the individual participating in the NAGALA (NAfld in the Gifu Area, Longitudinal Analysis) study at Murakami Memorial Hospital from 2004 to 2015, and 14297individuals apparently healthy at baseline were included in the study. Cox proportional hazards models were used to evaluate the associations between baseline TyG levels and incident of T2DM, and a two-piecewise linear regression model was use to examine the threshold effect of the baseline TyG on incident diabetes using a smoothing function. The threshold level (i.e., turning point) was determined using trial and error. A log likelihood ratio test was also conducted to compare the one-line linear regression model with a two-piecewise linear model. Results During a median follow-up period of 5.26 (women) and 5.88 (men) years, 47 women and 182 men developed Type 2 diabetes. The risk of diabetes was strongly associated with the baseline TyG index in the fully adjusted model in men but not in women, and no dose-dependent positive relationship between incident diabetes and TyG was observed across TyG tertiles. Intriguingly, two-piecewise linear regression analysis showed a U-shaped association between the TyG index and incident T2DM. The risk of incident diabetes decreased by around 90% in women with TyG < 7.27 (HR: 0.09; P = 0.0435) and 80% in men with TyG < 7.97 (HR 0.21, P = 0.002) with each increment of the TyG index after adjusting for confounders. In contrast, the risk of incident T2DM significantly elevated with the increase in TyG index in men with TyG > 7.97 (HR: 2.42, P < 0.001) and women with TyG > 7.29 (HR 2.76, P = 0.0166). Conclusions A U-shaped association was observed between the TyG index and incident T2DM among healthy individuals, with the TyG threshold of 7.97 in men and 7.27 in women. This information may be useful for reducing incident diabetes by maintaining the TyG index near these thresholds.

Genetically Elevated Serum Uric Acid and Renal Function in an Apparently Healthy Population

2019 ◽  
Vol 104 (3-4) ◽  
pp. 277-282
Author(s):  
Ji-Yong Ge ◽  
Yuan Ji ◽  
Zhen-Yan Zhu ◽  
Xun Li
Keyword(s):  
Renal Function ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Elevated Serum ◽  
Healthy Population ◽  
Apparently Healthy

scholarly journals C-reactive protein is associated with cigarette smoking-induced hyperfiltration and proteinuria in an apparently healthy population

2010 ◽  
Vol 33 (11) ◽  
pp. 1129-1136 ◽  
Author(s):  
Rani Sauriasari ◽  
Noriko Sakano ◽  
Da-Hong Wang ◽  
Jiro Takaki ◽  
Kei Takemoto ◽  
...  
Keyword(s):  
Cigarette Smoking ◽  
Healthy Population ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Apparently Healthy

Matrix Gla-protein: The calcification inhibitor in need of vitamin K

2008 ◽  
Vol 100 (10) ◽  
pp. 593-603 ◽  
Author(s):  
Ellen C. M. Cranenburg ◽  
Cees Vermeer ◽  
Leon J. Schurgers
Keyword(s):  
Vitamin K ◽  
Potent Inhibitor ◽  
Dominant Role ◽  
Matrix Gla Protein ◽  
Arterial Calcification ◽  
Healthy Population ◽  
Alternative Mechanism ◽  
Vascular Health ◽  
Calcification Detection ◽  
Apparently Healthy

SummaryAmong the proteins involved in vascular calcium metabolism, the vitamin K-dependent matrix Gla-protein (MGP) plays a dominant role. Although on a molecular level its mechanism of action is not completely understood, it is generally accepted that MGP is a potent inhibitor of arterial calcification. Its pivotal importance for vascular health is demonstrated by the fact that there seems to be no effective alternative mechanism for calcification inhibition in the vasculature. An optimal vitamin K intake is therefore important to maintain the risk and rate of calcification as low as possible. With the aid of conformation-specific antibodies MGP species in both tissue and the circulation have been detected in the healthy population, and significant differences were found in patients with cardiovascular disease (CVD). Using ELISA-based assays, uncarboxylated MGP (ucMGP) was demonstrated to be a promising biomarker for cardiovascular calcification detection. These assays may have potential value for identifying patients as well as apparently healthy subjects at high risk for CVD and/or cardiovascular calcification and for monitoring the treatment of CVD and vascular calcification.

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