Discrimination, Chronic Stress, and Mortality Among Black Americans: A Life Course Framework

Author(s):  
James S. Jackson ◽  
Darrell Hudson ◽  
Kiarri Kershaw ◽  
Briana Mezuk ◽  
Jane Rafferty ◽  
...  
Sociologija ◽  
2012 ◽  
Vol 54 (2) ◽  
pp. 211-226 ◽  
Author(s):  
Metka Kuhar ◽  
Herwig Reiter

This article reviews key-indicators of youth transitions in Slovenia over the last decades and highlights some of the inherent tensions. Against the background of the metaphor of ?frozen transitions?, which tries to grasp some of the contradictions between the speed of societal change and the stagnating development of youth towards independence, the article describes and reflects the development of youth transitions in the three domains of employment, housing and parenthood. The basis is a selection of indicators available in international data sets and surveys that allow to trace the change at least over the last two decades after the breakdown of Yugoslavia. Our findings indicate that transitions in Slovenia are frozen in all three domains, which challenges the usefulness of the conventional life course framework for studying post-communist contexts.


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S604-S604
Author(s):  
Rachel Donnelly

Abstract The health consequences of multiple family member deaths across the life course has received less attention in the bereavement literature. Moreover, recent research shows that black Americans are more likely than white Americans to lose multiple family members. I analyze longitudinal data from the Health and Retirement Study (1992-2014) to assess how multiple family member losses across the life course are associated with declines in health among older adults. Findings suggest that multiple family losses prior to midlife are associated with a number of indicators of poor health (e.g., functional limitations, cardiometabolic health) and steeper declines in health as individuals age. Losses after midlife additionally undermine health declines for older adults. Thus, family member loss functions as a cumulative burden of stress across the life course that erodes health in mid- and later-life. Family loss disproportionately burdens black Americans and serves as a unique source of disadvantage for black families.


2020 ◽  
Vol 15 (3) ◽  
pp. 341-348 ◽  
Author(s):  
Joseph Lunyera ◽  
John W. Stanifer ◽  
Clemontina A. Davenport ◽  
Dinushika Mohottige ◽  
Nrupen A. Bhavsar ◽  
...  

Background and objectivesLow socioeconomic status confers unfavorable health, but the degree and mechanisms by which life course socioeconomic status affects kidney health is unclear.Design, setting, participants, & measurementsWe examined the association between cumulative lifetime socioeconomic status and CKD in black Americans in the Jackson Heart Study. We used conditional process analysis to evaluate allostatic load as a potential mediator of this relation. Cumulative lifetime socioeconomic status was an age-standardized z-score, which has 1-SD units by definition, and derived from self-reported childhood socioeconomic status, education, and income at baseline. Allostatic load encompassed 11 baseline biomarkers subsuming neuroendocrine, metabolic, autonomic, and immune physiologic systems. CKD outcomes included prevalent CKD at baseline and eGFR decline and incident CKD over follow-up.ResultsAmong 3421 participants at baseline (mean age 55 years [SD 13]; 63% female), cumulative lifetime socioeconomic status ranged from −3.3 to 2.3, and 673 (20%) had prevalent CKD. After multivariable adjustment, lower cumulative lifetime socioeconomic status was associated with greater prevalence of CKD both directly (odds ratio [OR], 1.18; 95% confidence interval [95% CI], 1.04 to 1.33 per 1 SD and OR, 1.45; 95% CI, 1.15 to 1.83 in lowest versus highest tertile) and via higher allostatic load (OR, 1.09; 95% CI, 1.06 to 1.12 per 1 SD and OR, 1.17; 95% CI, 1.11 to 1.24 in lowest versus highest tertile). After a median follow-up of 8 years (interquartile range, 7–8 years), mean annual eGFR decline was 1 ml/min per 1.73 m2 (SD 2), and 254 out of 2043 (12%) participants developed incident CKD. Lower cumulative lifetime socioeconomic status was only indirectly associated with greater CKD incidence (OR, 1.04; 95% CI, 1.01 to 1.07 per 1 SD and OR, 1.08; 95% CI, 1.02 to 1.14 in lowest versus highest tertile) and modestly faster annual eGFR decline, in milliliters per minute (OR, 0.01; 95% CI, 0.00 to 0.02 per 1 SD and OR, 0.02; 95% CI, 0.00 to 0.04 in lowest versus highest tertile), via higher baseline allostatic load.ConclusionsLower cumulative lifetime socioeconomic status was substantially associated with CKD prevalence but modestly with CKD incidence and eGFR decline via baseline allostatic load.


2021 ◽  
pp. 019394592110370
Author(s):  
Rebecca D. Kehm ◽  
Dawn P. Misra ◽  
Jaime C. Slaughter-Acey ◽  
Theresa L. Osypuk

Prior studies of neighborhood racial segregation and intrauterine growth have not accounted for confounding factors in early life. We used the Life-Course Influences on Fetal Environment Study of births to Black women in metropolitan Detroit, 2009–2011, ( N = 1,408) to examine whether health and social conditions in childhood and adulthood confound or modify the association of neighborhood segregation (addresses during pregnancy geocoded to census tract racial composition) and gestational age-adjusted birthweight. Before adjusting for covariates, women living in a predominantly (≥75%) Black neighborhood gave birth to 47.3 grams (95% CI: –99.0, 4.4) lighter infants, on average, compared with women living in <75% Black neighborhoods. This association was confounded by adulthood (age at delivery, parity, neighborhood deprivation) and childhood (parental education, neighborhood racial composition) factors and modified by adulthood socioeconomic position. These findings underscore the complex relationship between neighborhood racial segregation and birth outcomes, which would be enhanced through a life course framework.


2017 ◽  
Vol 29 (4) ◽  
pp. 1443-1454 ◽  
Author(s):  
Carly E. Herbison ◽  
Karina Allen ◽  
Monique Robinson ◽  
John Newnham ◽  
Craig Pennell

AbstractThere is debate about the relative importance of timing of stressful events prenatally and over the life course and risk for subsequent depressive/anxious illness. The aim of this study was to examine the relative roles of prenatal stress and postnatal stress trajectories in predicting depression and anxiety in early adulthood in males and females. Exposure to life stress events was examined in the Western Australian Pregnancy Cohort (Raine) Study during pregnancy and ages 1, 2, 3, 5, 8, 10, 14, and 17 years. At age 20, offspring completed the Depression Anxiety Stress Scale. Prenatal stress and trajectories of stress events from age 1 to 17 were analyzed in linear regression analyses. Five postnatal stress trajectories were identified. In females, medium to high chronic stress exposure or exposure during puberty/adolescence predicted depression and anxiety symptoms while low or reduced stress exposure over the life course did not, after adjustment for relevant confounders. High stress early in pregnancy contributed to male depression/anxiety symptoms independent of postnatal stress trajectory. In females, postnatal stress trajectory was more important than prenatal stress in predicting depression/anxiety symptoms. Interventions focused on reducing and managing stress events around conception/pregnancy and exposure to chronic stress are likely to have beneficial outcomes on rates of depression and anxiety in adults.


Author(s):  
Heidi A. Hanson ◽  
Claire L. Leiser ◽  
Gretchen Bandoli ◽  
Brad H. Pollock ◽  
Margaret R. Karagas ◽  
...  

Abstract Life course research embraces the complexity of health and disease development, tackling the extensive interactions between genetics and environment. This interdisciplinary blueprint, or theoretical framework, offers a structure for research ideas and specifies relationships between related factors. Traditionally, methodological approaches attempt to reduce the complexity of these dynamic interactions and decompose health into component parts, ignoring the complex reciprocal interaction of factors that shape health over time. New methods that match the epistemological foundation of the life course framework are needed to fully explore adaptive, multilevel, and reciprocal interactions between individuals and their environment. The focus of this article is to (1) delineate the differences between lifespan and life course research, (2) articulate the importance of complex systems science as a methodological framework in the life course research toolbox to guide our research questions, (3) raise key questions that can be asked within the clinical and translational science domain utilizing this framework, and (4) provide recommendations for life course research implementation, charting the way forward. Recent advances in computational analytics, computer science, and data collection could be used to approximate, measure, and analyze the intertwining and dynamic nature of genetic and environmental factors involved in health development.


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