Prevention, Treatment and Control of Skin Diseases

2020 ◽  
pp. 73-82
Author(s):  
Fingani Annie Mphande
Keyword(s):  
Skin Diseases ◽  
And Control

scholarly journals Pedagogical conditions for the formation of counteraction to stressful phenomena in educational institutions

2021 ◽  
pp. 69-77
Author(s):  
Г.А. Арсаханова
Keyword(s):  
Skin Diseases ◽  
First Graders ◽  
Behavioral Disorder ◽  
Educational Institutions ◽  
Daily Routine ◽  
The Social ◽  
The Status ◽  
The Individual ◽  
And Control ◽  
Psychosomatic Diseases

Жизнедеятельность школьника полна проблем, решение которых приводит к стрессовым ситуациям. Прежде всего, это изменение социального статуса и изменение дошкольной деятельности ребенка на учебную. Статус школьника требует больше обязанностей, ответственности, дисциплинированности, структурированности режима дня, контроля собственных поступков. Даже в самом продуманном и хорошо налаженному жизни случаются ситуации, которые негативно влияют на детей и приводят к стрессу. Первоклассники не всегда готовы к таким изменениям, что вызывает ряд психофизиологических и поведенческих проявлений. В состоянии стресса поведение ребенка дезорганизовывается, наблюдаются неконтролируемые движения, определенные речевые отклонения, появляются эмоции, не соответствующие культуре взаимоотношений. Стресс – это сильное проявление эмоций вызывает комплексную физиологическую реакцию, это состояние душевного и поведенческого расстройства, связанного с неспособностью личности целесообразно действовать в соответствующих ситуациях. Из-за недостаточной сформированности эмоциональной сферы в школьном возрасте при частых стрессовых ситуациях у ребенка исчезает аппетит, наступает депрессия, снижается интерес к учебе, общению, наступает апатия. Стрессовые ситуации негативно сказываются на здоровье школьника, у ребенка появляется целый «букет» опасных психосоматических заболеваний: мигрень, гипертония, астма, артрит, аллергия, диабет, кожные болезни и тому подобное. The student's life is full of problems, the solution of which leads to stressful situations. First of all, this is a change in the social status and a change in the preschool activity of the child to the educational one. The status of a student requires more responsibilities, responsibility, discipline, structured daily routine, and control of one's own actions. Even in the most thoughtful and well-established life, there are situations that negatively affect children and lead to stress. First-graders are not always ready for such changes, which causes a number of psychophysiological and behavioral manifestations. In a state of stress, the child's behavior is disorganized, uncontrolled movements are observed, certain speech deviations appear, emotions that do not correspond to the culture of relationships. Stress-this strong manifestation of emotions causes a complex physiological reaction, this is a state of mental and behavioral disorder associated with the inability of the individual to act appropriately in appropriate situations. Due to the lack of formation of the emotional sphere at school age, with frequent stressful situations, the child's appetite disappears, depression sets in, interest in learning, communication decreases, and apathy sets in. Stressful situations negatively affect the health of the student, the child has a whole "bouquet" of dangerous psychosomatic diseases: migraine, hypertension, asthma, arthritis, allergies, diabetes, skin diseases, and the like.

scholarly journals Keratinocyte differentiation and proteolytic pathways in skin (patho)physiology

2021 ◽  
Author(s):  
Eleni Zingkou ◽  
Georgios Pampalakis ◽  
Georgia Sotiropoulou
Keyword(s):  
Skin Diseases ◽  
Seborrheic Dermatitis ◽  
Epidermal Differentiation ◽  
Keratinocyte Differentiation ◽  
Altered Expression ◽  
Netherton Syndrome ◽  
Skin Biopsies ◽  
And Control ◽  
Histology And Immunohistochemistry ◽  
Desmosomal Protein

Epidermis is a stratified epithelium that forms the barrier between the organism and its environment. It is mainly composed of keratinocytes at different stages of differentiation. Stratum corneum is the outermost layer of the epidermis and is formed of multiple layers of anucleated keratinocytes called corneocytes. We aim to highlight the roles of epidermal differentiation and proteolysis in skin diseases. Skin biopsies isolated from Spink5-/- mice, the established model of Netherton syndrome (NS), and from patients with NS, seborrheic dermatitis (SD) and psoriasis, as well as healthy controls, were analyzed by histology and immunohistochemistry. Our results showed that NS, SD, and psoriasis are all characterized by abnormal epidermal differentiation, manifested by hyperplasia, hyperkeratosis, and parakeratosis. At the molecular level, abnormal differentiation is accompanied by increased expression of involucrin and decreased expression of loricrin in NS and psoriasis. Increased epidermal proteolysis associated with increased kallikrein-related peptidases (KLK) expression is also observed in both NS and psoriatic epidermis. Further, reduced expression of desmosomal proteins is observed in NS but increased in psoriasis. Since desmosomal protein are proteolytic substrates and control keratinocyte differentiation, their altered expression directly links epidermal proteolysis to differentiation. In conclusion, abnormal cellular differentiation and proteolysis are interconnected and underlie the pathology of NS, SD and psoriasis.

scholarly journals Pattern of skin diseases and common drugs prescribed in dermatology OPD of an Indian tertiary care hospital

2016 ◽  
Vol 6 (1) ◽  
pp. 203
Author(s):  
Surabhi Gupta ◽  
Wase Khan ◽  
Arvind Krishna
Keyword(s):  
Skin Diseases ◽  
Disease Incidence ◽  
Drug Prescription ◽  
Tertiary Care ◽  
Care Hospital ◽  
Drug Induced ◽  
Single Center Study ◽  
Cutaneous Reactions ◽  
Common Group ◽  
And Control

Background: The pattern of skin diseases varies from one country to another and across different parts within the same country. The prevalence of skin disease in the general population varies from 11.16 % to 63 %. Patients in their second and third decades of age form the largest group of population. A proper treatment is essential for cure and control of these diseases. The aim of the study was to find the pattern of skin diseases in Meerut district of western UP and common group of drugs prescribed for them.Methods: It was a prospective, observational, single center study. The relevant data was collected from OPD prescriptions by taking photographs of the prescriptions and details were filled in the predesigned proforma.Results: A total of 500 OPD prescriptions were collected and analyzed for demographic profile, disease incidence and drug prescription. Three most common conditions observed were tinea (15.25%), acne (12.36%), drug induced cutaneous reactions (10.11%). Antifungals (19.4%), Antibiotics (17.6%), Antihistamines (15.9%) and Corticosteroids (9.4%) were the most common class of drugs prescribed. Dosage forms prescribed were mostly topical (51.2%) in the form of ointments, creams, lotions, shampoo, powders.Conclusions: From our study we found out that tinea (15.25%) and acne (12.36%) were more common in this region and antifungals were most the commonly prescribed group of drugs (19.4%). Number of drugs/prescription was much higher (4.1) than the recommended limit of 2 approved by WHO and practice of polypharmacy was also commonly seen.

scholarly journals Association of Streptococcus with Guttate Psoriasis: An Observational Study at Two Tertiary Care Hospitals in Dhaka

2013 ◽  
Vol 5 (2) ◽  
pp. 91-94
Author(s):  
Md Akram Hossain ◽  
Md. Eakub Ali ◽  
Ishrat Bhuiyan ◽  
Md. Shahadat Hossain ◽  
Biswas Shahin
Keyword(s):  
Sore Throat ◽  
Skin Diseases ◽  
Tertiary Care ◽  
Control Group ◽  
Case Group ◽  
College Hospital ◽  
Medical College ◽  
History Of ◽  
Guttate Psoriasis ◽  
And Control

Background: Psoriasis is multifactorial in origin. Streptococcal infection, sore throat has been claimed to be an  infectious  cause.Objective: The  purpose  of  the  present  study  was  to  observe  the  association  of Streptococcus with guttate psoriasis.Methodology: This was an observational case-control study which was conducted in the Department of Dermatology & Venereology at Bangabandhu Sheikh Mujib Medical University (BSMMU), & Shaheed Suhrawardy Medical College hospital (ShSMCH) in Dhaka city of Bangladesh during the period of February 2012  to October 2012. Patients clinically and histopathologically diagnosed as psoriasis were selected as case group and patients with skin diseases other than psoriasis were selected as control group.Results: A total of 115 patients were included in this study of which 64 patients were in case group and the rest 51 patients were designated as control group. The mean age was 30.73±14.69 years and 26.47±12.64 years in cases and control groups respectively (p>0.05). About 66.6% patients gave a positive history of sore throat. ASO titer was raised (>200 IU/ml) in 25(83.3%) patients of guttate psoriasis and 5(23.8%) in patients of their non-psoriatic controls (p<0.05). Streptococcus pyogenes was found in 9(30.0%) patients of case group and only 2(9.5%) patients were found in their control group.Conclusion: Streptococcal throat infections are associated with guttate psoriasis patients.DOI: http://dx.doi.org/10.3329/jssmc.v5i2.20763J Shaheed Suhrawardy Med Coll, 2013;5(2):91-94

scholarly journals Evaluation of the observance of health protocols and requirements of the environmental and occupational health center against COVID-19 in men’s hairdresser salons of Birjand, Iran, in 2020

2021 ◽  
pp. 365-374
Keyword(s):  
Skin Diseases ◽  
Food Hygiene ◽  
Workplace Health ◽  
Cross Sectional ◽  
Significance Level ◽  
Global Pandemic ◽  
Spss Software ◽  
And Control ◽  
Environmental And Occupational Health ◽  
Health Experts

Background and Aims: The Coronavirus has become a global pandemic that has affected most countries in the world. Hairdresser salon as a public place can transmit infectious diseases, such as AIDS, hepatitis as well as viral, fungal, and skin diseases that are often due to non-compliance with hygiene principles. This study aimed to investigate the observance of health instructions regarding the prevention and control of Coronavirus disease in men's hairdresser salons in Birjand, Iran, in 2020. Materials and Methods: In this cross-sectional descriptive study, 145 hairdresser salons in Birjand were selected through the random sampling method. The data collection tool was a checklist that was prepared according to the guidelines of the Ministry of Health and Medical Education. The obtained data were analyzed in SPSS software (version 18) using Mann-Whitney and Kruskal-Wallis tests at a significance level of ≤ 0.05. Results: The findings showed that the total mean score of the observance of workplace health and hygiene guidelines was 24.28±2.52 and the average observance of health instructions in the field of health and personal protection, building hygiene, tool and equipment hygiene, and food hygiene were 13.73±2.08, 2.31±0.68, 7.22±0.64, and 1.01±0.11, respectively. Observance of health instructions was found to have a significant relationship with age and geographical region (P≤0.05). Conclusion: According to the results, it seems necessary to train hairdressers in terms of observing health instructions. Moreover, men’s hairdresser salons should be continuously monitored by health experts.

Control of Metal Alloy Oxidation with Electric Fields

1973 ◽  
Vol 31 ◽  
pp. 164-165
Author(s):  
R. R. Dils ◽  
P. S. Follansbee
Keyword(s):  
Electric Fields ◽  
Oxidation Process ◽  
Base Alloy ◽  
Oxide Surface ◽  
Platinum Electrodes ◽  
Insulating Layer ◽  
Iron Base Alloy ◽  
Alloy Oxidation ◽  
Aluminum Oxide Layer ◽  
And Control

Electric fields have been applied across oxides growing on a high temperature alloy and control of the oxidation of the material has been demonstrated. At present, three-fold increases in the oxidation rate have been measured in accelerating fields and the oxidation process has been completely stopped in a retarding field.The experiments have been conducted with an iron-base alloy, Pe 25Cr 5A1 0.1Y, although, in principle, any alloy capable of forming an adherent aluminum oxide layer during oxidation can be used. A specimen is polished and oxidized to produce a thin, uniform insulating layer on one surface. Three platinum electrodes are sputtered on the oxide surface and the specimen is reoxidized.

Evidence for a Blood Ganglion Barrier in the Superior Cervical Ganglion of the Rat

1982 ◽  
Vol 40 ◽  
pp. 204-204
Author(s):  
D. M. DePace
Keyword(s):  
Blood Vessels ◽  
Superior Cervical Ganglion ◽  
Peripheral Nerves ◽  
Time Schedule ◽  
Transmission Electron ◽  
Cervical Ganglion ◽  
The Central Nervous System ◽  
Cervical Ganglia ◽  
Capillary Circulation ◽  
And Control

The majority of blood vessels in the superior cervical ganglion possess a continuous endothelium with tight junctions. These same features have been associated with the blood brain barrier of the central nervous system and peripheral nerves. These vessels may perform a barrier function between the capillary circulation and the superior cervical ganglion. The permeability of the blood vessels in the superior cervical ganglion of the rat was tested by intravenous injection of horseradish peroxidase (HRP). Three experimental groups of four animals each were given intravenous HRP (Sigma Type II) in a dosage of.08 to.15 mg/gm body weight in.5 ml of.85% saline. The animals were sacrificed at five, ten or 15 minutes following administration of the tracer. Superior cervical ganglia were quickly removed and fixed by immersion in 2.5% glutaraldehyde in Sorenson's.1M phosphate buffer, pH 7.4. Three control animals received,5ml of saline without HRP. These were sacrificed on the same time schedule. Tissues from experimental and control animals were reacted for peroxidase activity and then processed for routine transmission electron microscopy.

Effects of renovascular hypertension on rat adrenal zona glomerulosa

1978 ◽  
Vol 36 (2) ◽  
pp. 582-583
Author(s):  
G. Mazzocchi ◽  
P. Rebuffat ◽  
C. Robba ◽  
P. Vassanelli ◽  
G. G. Nussdorfer
Keyword(s):  
Renovascular Hypertension ◽  
Left Kidney ◽  
Renin Angiotensin System ◽  
Plasma Renin ◽  
Zona Glomerulosa ◽  
Ultrastructural Changes ◽  
Albino Rats ◽  
Left Renal Artery ◽  
Angiotensin System ◽  
And Control

It is well known that the rat adrenal zona glomerulosa steroidogenic activity is controlled by the renin-angiotensin system. The ultrastructural changes in the rat zona glomerulosa cells induced by renovascular hypertension were described previously, but as far as we are aware no correlated biochemical and morphometric investigations were performed.Twenty adult male albino rats were divided into 2 experimental groups. One group was subjected to restriction of blood flow to the left kidney by the application of a silver clip about the left renal artery. The other group was sham-operated and served as a control. Renovascular hypertension developed in about 10 days: sistolic blood pressure averaged 165 ± 6. 4 mmHg, whereas it was about 110 ± 3. 8 mmHg in the control animals. The hypertensive and control rats were sacrificed 20 days after the operation. The blood was collected and plasma renin activity was determined by radioimmunological methods. The aldosterone concentration was radioimmunologically assayed both in the plasma and in the homogenate of the left capsular adrenal gland.

X-Ray Replication of Submicrometer Linewidth Patterns

1977 ◽  
Vol 35 ◽  
pp. 136-137
Author(s):  
Henry I. Smith ◽  
D.C. Flanders
Keyword(s):  
Electron Beam Lithography ◽  
Cross Sectional ◽  
X Ray ◽  
Electron Backscattering ◽  
Spatial Frequencies ◽  
Cross Sectional Profile ◽  
Carbon Foils ◽  
Sectional Profile ◽  
And Control ◽  
Soft Radiation

Scanning electron beam lithography has been used for a number of years to write submicrometer linewidth patterns in radiation sensitive films (resist films) on substrates. On semi-infinite substrates, electron backscattering severely limits the exposure latitude and control of cross-sectional profile for patterns having fundamental spatial frequencies below about 4000 Å(l),Recently, STEM'S have been used to write patterns with linewidths below 100 Å. To avoid the detrimental effects of electron backscattering however, the substrates had to be carbon foils about 100 Å thick (2,3). X-ray lithography using the very soft radiation in the range 10 - 50 Å avoids the problem of backscattering and thus permits one to replicate on semi-infinite substrates patterns with linewidths of the order of 1000 Å and less, and in addition provides means for controlling cross-sectional profiles. X-radiation in the range 4-10 Å on the other hand is appropriate for replicating patterns in the linewidth range above about 3000 Å, and thus is most appropriate for microelectronic applications (4 - 6).

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