Epidemiological Trends and Risk Factors of Colorectal Cancer: Implications for Population-Based Organized Service Screening

This review article contains a concise consideration of genetic and environmental risk factors for colorectal cancer. Known risk factors associated with colorectal cancer include familial and hereditary factors and lifestyle-related and ecological factors. Lifestyle factors are significant because of the potential for improving our understanding of the disease. Physical inactivity, obesity, smoking and alcohol consumption can also be addressed through therapeutic interventions. We also made efforts to systematize available literature and data on epidemiology, diagnosis, type and nature of symptoms and disease stages. Further study of colorectal cancer and progress made globally is crucial to inform future strategies in controlling the disease’s burden through population-based preventative initiatives.

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Risk factors for cardiovascular mortality in patients with colorectal cancer: a population-based study

International Journal of Clinical Oncology ◽

10.1007/s10147-018-01382-x ◽

2019 ◽

Vol 24 (5) ◽

pp. 501-507

Author(s):

Apostolos Gaitanidis ◽

Michail Spathakis ◽

Christos Tsalikidis ◽

Michail Alevizakos ◽

Alexandra Tsaroucha ◽

...

Keyword(s):

Colorectal Cancer ◽

Risk Factors ◽

Cardiovascular Mortality ◽

Population Based ◽

Population Based Study

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Mo1613 - Risk Factors of Young-Onset Colorectal Cancer: Analysis of a Large Population-Based Registry

Gastroenterology ◽

10.1016/s0016-5085(18)32664-7 ◽

2018 ◽

Vol 154 (6) ◽

pp. S-769-S-770

Author(s):

Danial Daneshvar ◽

Youssef El Douaihy ◽

Maryam Bayat Mokhtari ◽

Lilliane Deeb

Keyword(s):

Colorectal Cancer ◽

Risk Factors ◽

Large Population ◽

Population Based ◽

Young Onset ◽

Population Based Registry

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Mo1788 – Prevalence and Risk Factors of First-Ever Occurrence of Colorectal Cancer Post Diverticulitis in Adults in the United States Between 2013 and 2018: A Population-Based National Study

Gastroenterology ◽

10.1016/s0016-5085(19)39055-9 ◽

2019 ◽

Vol 156 (6) ◽

pp. S-837-S-838

Author(s):

Emad Mansoor ◽

Chiara Maruggi ◽

Mohannad Abou Saleh ◽

Gerard A. Isenberg ◽

Richard C. Wong ◽

...

Keyword(s):

Colorectal Cancer ◽

United States ◽

Risk Factors ◽

The United States ◽

Population Based ◽

National Study

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The Use of Multiple Correspondence Analysis and K-means to Explore Associations between Risk Factors and Patient Characteristics in Colorectal Cancer (Preprint)

10.2196/preprints.29056 ◽

2021 ◽

Author(s):

Dídac Florensa ◽

Jordi Mateo ◽

Francesc Solsona ◽

Teresa Pedrol ◽

Miquel Mesas ◽

...

Keyword(s):

Colorectal Cancer ◽

Risk Factors ◽

Correspondence Analysis ◽

Multiple Correspondence Analysis ◽

Clinical History ◽

Patient Characteristics ◽

Population Based ◽

Cross Sectional ◽

Risk Of Death ◽

Increased Risk

BACKGROUND Previous works have shown that risk factors are associated with an increased risk of colorectal cancer. OBJECTIVE The purpose of this study was to detect these associations in the region of Lleida (Catalonia) using Multiple Correspondence Analysis (MCA) and K-means. METHODS The cross-sectional study was made up of 1,085 colorectal cancer episodes between 2012 and 2015, extracted from the Population-based Cancer Registry (PCR) for the province of Lleida (Spain), the Primary Care Centers database and the Catalan Health Service Register. The relations between risk factors and patient characteristics were identified using MCA and K-means. RESULTS The combination of these techniques helps to detect clusters of patients with similars risk factors. Risk of death is associated with elderly people and obesity or overweight. Stage III is related with people aged ≥65 and rural/semi-urban population while younger people were related with stage 0. CONCLUSIONS MCA and K-means were a significant help for detecting associations between risk factors and patient characteristics. These techniques have proven to be effective tools for analyzing the incidence of some factors in colorectal cancer. The outcomes obtained help to corroborate suspected trends, as well as stimulating new hypotheses about the previous clinical history and how to prevent it.

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