A kink model of native collagen

1973 ◽  
Vol 251 (12) ◽  
pp. 1044-1056 ◽  
Author(s):  
Th. Nemetschek ◽  
R. Hosemann
Keyword(s):  
Native Collagen ◽  
Kink Model

Fine Structure of Platelet Interaction with a New Microcrystalline Collagen Preparation

1974 ◽  
Vol 32 ◽  
pp. 58-59
Author(s):  
W. H. Zucker ◽  
R. G. Mason
Keyword(s):  
Fine Structure ◽  
Platelet Aggregation ◽  
Hydrochloric Acid ◽  
Whole Blood ◽  
Platelet Adhesion ◽  
Hemostatic Agent ◽  
Native Collagen ◽  
Fibrillar Morphology ◽  
Clinical Interest ◽  
New Form

Platelet adhesion initiates platelet aggregation and is an important component of the hemostatic process. Since the development of a new form of collagen as a topical hemostatic agent is of both basic and clinical interest, an ultrastructural and hematologic study of the interaction of platelets with the microcrystalline collagen preparation was undertaken.In this study, whole blood anticoagulated with EDTA was used in order to inhibit aggregation and permit study of platelet adhesion to collagen as an isolated event. The microcrystalline collagen was prepared from bovine dermal corium; milling was with sharp blades. The preparation consists of partial hydrochloric acid amine collagen salts and retains much of the fibrillar morphology of native collagen.

Banded Structures in the Connective Tissue of Meningioma

1976 ◽  
Vol 34 ◽  
pp. 234-235
Author(s):  
C. N. Sun ◽  
H. J. White
Keyword(s):  
Connective Tissue ◽  
Osmium Tetroxide ◽  
Uranyl Acetate ◽  
Collagen Fibrils ◽  
Lead Citrate ◽  
Connective Tissues ◽  
Native Collagen ◽  
Routine Procedures

Previously, we have reported on extracellular cross-striated banded structures in human connective tissues of a variety of organs (1). Since then, more material has been examined and other techniques applied. Recently, we studied a fibrocytic meningioma of the falx. After the specimen was fixed in 4% buffered glutaraldehyde and post-fixed in 1% buffered osmium tetroxide, other routine procedures were followed for embedding in Epon 812. Sections were stained with uranyl acetate and lead citrate. There were numerous cross striated banded structures in aggregated bundle forms found in the connecfive tissue of the tumor. The banded material has a periodicity of about 450 Å and where it assumes a filamentous arrangement, appears to be about 800 Å in diameter. In comparison with the vicinal native collagen fibrils, the banded material Is sometimes about twice the diameter of native collagen.

scholarly journals Quantum kink model and SU(2) symmetry: spin interpretation andT-violation

1998 ◽  
Vol 31 (28) ◽  
pp. 6081-6085 ◽  
Author(s):  
K G Zloshchastiev
Keyword(s):  
Kink Model

Structural investigations on native collagen type I fibrils using AFM

2007 ◽  
Vol 354 (1) ◽  
pp. 27-32 ◽  
Author(s):  
Stefan Strasser ◽  
Albert Zink ◽  
Marek Janko ◽  
Wolfgang M. Heckl ◽  
Stefan Thalhammer
Keyword(s):  
Collagen Type ◽  
Collagen Type I ◽  
Type I ◽  
Structural Investigations ◽  
Native Collagen

Phase partitioning of the chain defects in ethylene-butene copolymers in the framework of the crystalline chain kink model

Polymer ◽  
1994 ◽  
Vol 35 (10) ◽  
pp. 2049-2055 ◽  
Author(s):  
Valérie Gaucher ◽  
Roland Séguéla
Keyword(s):  
Phase Partitioning ◽  
Chain Defects ◽  
Kink Model

Dielectric and pyroelectric characterization of anionic and native collagen

1996 ◽  
Vol 36 (24) ◽  
pp. 2932-2938 ◽  
Author(s):  
Ana Maria De Guzzi Plepis ◽  
Gilberto Goissis ◽  
Dilip K. Das-Gupta
Keyword(s):  
Native Collagen

Cell proliferation and migration on collagen substrata in vitro

1980 ◽  
Vol 41 (1) ◽  
pp. 159-175
Author(s):  
S.L. Schor
Keyword(s):  
Cell Proliferation ◽  
Cell Migration ◽  
Collagen Gel ◽  
Collagen Fibres ◽  
3 Dimensional ◽  
Cell Proliferation And Migration ◽  
Native Collagen ◽  
And Migration ◽  
Collagen Gel Matrix ◽  
Proliferation And Migration

Quantitative data are presented regarding cell proliferation and migration on (a) collagen films (b) the surface of 3-dimensional gels of native collagen fibres and (c) within the 3-dimensional collagen gel matrix, as part of a study of the effects of the extracellular matrix on cell behaviour. The nature of the collagen environment was found to influence the proliferation of certain cell types, but not of others. For example, HeLa cells proliferate at approximately the same rate and reach the same saturation cell densities on all of the collagen substrata, while human skin fibroblasts grow more slowly within the 3-dimensional collagen gel matrix compared with cells either on the gel surface or on collagen films. The 3-dimensional gels of native collagen fibres may also be used to study cell migration on the gel surface, as well as cell migration (or ‘infiltration’) from the gel surface into the 3-dimensional collagen matrix. Two methods have been used to obtain quantitative information concerning cell infiltration into the collagen gel, one involving the selective removal of cells from the gel surface, while the other relies on direct microscopic examination. Of the cells examined to date, epithelial cells (both normal and tumour) do not show infiltrative behaviour, while both normal and virally transformed fibroblasts, as well as tumour cells of non-epithelial origin (e.g. melanoma), do infiltrate into the collagen gel matrix, at rates which vary considerably according to cell type.

Analysis of Native Collagen Monomers and Oligomers by Size-Exclusion High-Performance Liquid Chromatography and Its Application

1993 ◽  
Vol 212 (2) ◽  
pp. 436-445 ◽  
Author(s):  
R.A. Condell ◽  
V.P. Hanko ◽  
E.A. Larenas ◽  
G. Wallace ◽  
K.A. Mccullough
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Size Exclusion ◽  
Native Collagen

scholarly journals The use of Dermacell® in Fingertip Injury

2019 ◽  
Vol 1 (2) ◽  
pp. 14-22 ◽  
Author(s):  
Wu, Tsung-Hsuan ◽  
Giampietro Bertasi
Keyword(s):  
Immune Response ◽  
Collagen Scaffold ◽  
Tissue Scaffolds ◽  
Cellular Growth ◽  
Collagen Structure ◽  
Tissue Remodelling ◽  
Fingertip Injury ◽  
Viable Cells ◽  
Native Collagen ◽  
Immunogenic Response

Matrices or tissue scaffolds provide a collagen structure for tissue remodelling while the removal of viable cells aims to minimize or prevent inflammatory or immunogenic response. Allograft collagen scaffold can support the patient’s own cellular ingrowth, ingeneered to minimize an immune response and to yeld a bio-compatible matrix and support incoming cellular growth. The decellyularized dermis retains its growth factors, native collagen scaffold, and elastin, thanks to a LifeNet Health proprietaryprocessin technology.

scholarly journals An overview on therapeutic potential and various applications of microbial collagenases

2017 ◽  
Vol 7 (6) ◽  
pp. 17
Author(s):  
Wamik Azmi ◽  
Shikha Chauhan ◽  
Manisha Gautam
Keyword(s):  
Connective Tissue ◽  
Human Body ◽  
Food Industry ◽  
Therapeutic Potential ◽  
Practical Interest ◽  
Scar Tissue ◽  
Physiological Conditions ◽  
Native Collagen ◽  
Successful Transplantation ◽  
Connective Tissue Metabolism

Collagen is the most widely distributed class of proteins in the human body. Monomers of collagen are constantly being synthesized and degraded throughout the development of a healthy individual to adulthood. The collagenase subfamily found in human matrix (metalloproteinases), are capable of hydrolyzing native collagen under physiological conditions. Collagenases are produced by specific cells involved in repairs and remodelling processes and plays important role in connective tissue metabolism. Present article focus on the major sources, properties and therapeutic aspects of microbial collagenases in their relation with various diseases and its applications in medical and food industry. Collagenolytic enzymes are highly specific for collagen and have been the focus of much practical interest with respect to cosmetic, medical and food based applications. The most common uses of these enzymes appear to be in medicine as they have been used to treat burns and ulcers, to eliminate scar tissue and play an important role in the successful transplantation of specific organs.

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