Opposite response of maize ZmCCT to photoperiod due to transposon jumping

2021 ◽  
Author(s):  
Shuyang Zhong ◽  
Hangqin Liu ◽  
Yan Li ◽  
Zhongwei Lin
Keyword(s):  
Opposite Response

scholarly journals Hyperpolarized 13C-glucose magnetic resonance highlights reduced aerobic glycolysis in vivo in infiltrative glioblastoma

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Mor Mishkovsky ◽  
Olga Gusyatiner ◽  
Bernard Lanz ◽  
Cristina Cudalbu ◽  
Irene Vassallo ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Tumor Recurrence ◽  
Aerobic Glycolysis ◽  
Imaging Techniques ◽  
Tumor Type ◽  
Hyperpolarized 13C ◽  
Metabolic Heterogeneity ◽  
Metabolic Information ◽  
Opposite Response

AbstractGlioblastoma (GBM) is the most aggressive brain tumor type in adults. GBM is heterogeneous, with a compact core lesion surrounded by an invasive tumor front. This front is highly relevant for tumor recurrence but is generally non-detectable using standard imaging techniques. Recent studies demonstrated distinct metabolic profiles of the invasive phenotype in GBM. Magnetic resonance (MR) of hyperpolarized 13C-labeled probes is a rapidly advancing field that provides real-time metabolic information. Here, we applied hyperpolarized 13C-glucose MR to mouse GBM models. Compared to controls, the amount of lactate produced from hyperpolarized glucose was higher in the compact GBM model, consistent with the accepted “Warburg effect”. However, the opposite response was observed in models reflecting the invasive zone, with less lactate produced than in controls, implying a reduction in aerobic glycolysis. These striking differences could be used to map the metabolic heterogeneity in GBM and to visualize the infiltrative front of GBM.

Dual-emission carbon dots based ratiometric fluorescent sensor with opposite response for detecting copper (II)

2021 ◽  
Vol 196 ◽  
pp. 109803
Author(s):  
Gengli Huang ◽  
Xueli Luo ◽  
Xie He ◽  
Yong Han ◽  
Haiping Zhao ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Fluorescent Sensor ◽  
Dual Emission ◽  
Opposite Response

scholarly journals JAMP Optimizes ERAD to Protect Cells from Unfolded Proteins

2008 ◽  
Vol 19 (11) ◽  
pp. 5019-5028 ◽  
Author(s):  
Marianna Tcherpakov ◽  
Limor Broday ◽  
Agnes Delaunay ◽  
Takayuki Kadoya ◽  
Ashwani Khurana ◽  
...  
Keyword(s):  
Caenorhabditis Elegans ◽  
Er Stress ◽  
Transmembrane Protein ◽  
26S Proteasome ◽  
Misfolded Proteins ◽  
Unfolded Proteins ◽  
Cellular Homeostasis ◽  
Channel Proteins ◽  
Proteasome Subunits ◽  
Opposite Response

Clearance of misfolded proteins from the ER is central for maintenance of cellular homeostasis. This process requires coordinated recognition, ER-cytosol translocation, and finally ubiquitination-dependent proteasomal degradation. Here, we identify an ER resident seven-transmembrane protein (JAMP) that links ER chaperones, channel proteins, ubiquitin ligases, and 26S proteasome subunits, thereby optimizing degradation of misfolded proteins. Elevated JAMP expression promotes localization of proteasomes at the ER, with a concomitant effect on degradation of specific ER-resident misfolded proteins, whereas inhibiting JAMP promotes the opposite response. Correspondingly, a jamp-1 deleted Caenorhabditis elegans strain exhibits hypersensitivity to ER stress and increased UPR. Using biochemical and genetic approaches, we identify JAMP as important component for coordinated clearance of misfolded proteins from the ER.

scholarly journals Precoce and opposite response of proteasome activity after acute or chronic exposure of C. elegans to γ-radiation

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Cécile Dubois ◽  
Catherine Lecomte ◽  
Sébastien Pyr dit Ruys ◽  
Mira Kuzmic ◽  
Claire Della-Vedova ◽  
...  
Keyword(s):  
Chronic Exposure ◽  
Proteasome Activity ◽  
Γ Radiation ◽  
C Elegans ◽  
Opposite Response

An opposite response of the low-latitude ionosphere at Asian and American sectors during storm recovery phase: drivers from below and above

2020 ◽  
Author(s):  
Chao Xiong ◽  
Hermann Luehr ◽  
Yosuke Yamazaki
Keyword(s):  
Geomagnetic Storms ◽  
Recovery Phase ◽  
The Philippines ◽  
Lower Atmosphere ◽  
Electron Content ◽  
Early Recovery ◽  
Total Electron ◽  
Ionospheric Response ◽  
Swarm Satellites ◽  
Opposite Response

<p>The energy input from the solar wind and magnetosphere is thought to dominate the ionospheric response during geomagnetic storms. However, at the storm recovery phase, the role of forces from lower atmosphere could be as important as that from above. In this study, we focused on the geomagnetic storm happened on 6–11 September 2017. The ground-based total electron content (TEC) data as well as the F region in situ electron density measured by the Swarm satellites reveals that at low and equatorial latitudes the dayside ionosphere shows as prominent positive and negative responses at the Asian and American longitudinal sectors, respectively. The global distribution of thermospheric O/N2 ratio measured by global ultraviolet imager on board the TIMED satellite cannot well explain such longitudinally opposite response of the ionosphere. Comparison between the equatorial electrojet variations from stations at Huancayo in Peru and Davao in the Philippines suggests that the longitudinally opposite ionospheric response should be closely associated with the interplay of E region electrodynamics. By further applying nonmigrating tidal analysis to the ground‐based TEC data, we find that the diurnal tidal components, D0 and DW2, as well as the semidiurnal component SW1, are clearly enhanced over prestorm days and persist into the early recovery phase, indicating the possibility of lower atmospheric forcing contributing to the longitudinally opposite response of the ionosphere on 9–11 September 2017.</p>

Stimulus Sensitivity and Stimulus Intensity Control

1969 ◽  
Vol 28 (1) ◽  
pp. 71-78 ◽  
Author(s):  
Julian Silverman ◽  
Monte Buchsbaum ◽  
Robert Henkin
Keyword(s):  
Stimulus Intensity ◽  
Control Mechanism ◽  
Sensory Threshold ◽  
Response Tendency ◽  
Low Intensity ◽  
Intensity Control ◽  
The Central Nervous System ◽  
And Performance ◽  
Light Flashes ◽  
Opposite Response

Previous research had suggested a relationship between averaged cortical evoked response (AER) characteristics and the perception of stimulus intensity. In this study a systematic relationship was hypothesized between AER characteristics and performance on traditional sensory threshold procedures. Averaged evoked responses to light flashes and performances on a battery of psychophysical tasks were measured in 20 normal volunteers. Ss with one AER pattern were sensitive to low-intensity stimulation; Ss with another AER pattern exhibited the opposite response tendency. These findings were interpreted in terms of a theoretical construct regarding a stimulus-intensity control mechanism in the central nervous system.

scholarly journals Direction, ontogeny, and mechanism of the temperature-size rule operating in a large marine crab, Chionoecetes opilio

2020 ◽  
Author(s):  
Bernard Sainte-Marie ◽  
Jean-François Ouellet ◽  
Hélène Dionne
Keyword(s):  
Temperature Effects ◽  
Laboratory Experiments ◽  
Snow Crab ◽  
Temperature Sensitive ◽  
Chionoecetes Opilio ◽  
Determinate Growth ◽  
Settlement Size ◽  
Initial Difference ◽  
Time Invariant ◽  
Opposite Response

Abstract The classic temperature-size rule (TSR) states that ectotherms mature smaller in warmer than in colder conditions; the reverse TSR is the opposite response. We combined field observations with laboratory experiments and published information to synthesise the response of snow crab (Chionoecetes opilio), a marine brachyuran with determinate growth, to temperature. Size at onset of physiological maturation/maturity and after terminal moult (TM) were positively related to temperature, thus indicating the reverse TSR. Moult increment varied little with temperature, but crabs were larger at instar in colder than in warmer water due to an initial difference in settlement size that propagated to higher instars, suggesting classic TSR prior to settlement. The pattern of increasing TM size with temperature was caused by crabs moulting more times before TM in warmer than in colder water. Intermoult period (IP) declined exponentially with temperature, and lower instars were more temperature sensitive than higher instars. Temperature effects on IP were strong enough to explain changes in size and instar number at TM under a possible time-invariant maturation schedule. Skip moulting was observed in the smallest crabs reared in the laboratory and resulted in high mortality. The reverse TSR in snow crab seems to be adaptive to coping with ectotherm predation.

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