scholarly journals Effective treatment of symptomatic diabetic polyneuropathy by high-frequency external muscle stimulation

Diabetologia ◽  
2005 ◽  
Vol 48 (5) ◽  
pp. 824-828 ◽  
Author(s):  
L. Reichstein ◽  
S. Labrenz ◽  
D. Ziegler ◽  
S. Martin
2014 ◽  
Vol 224 (3) ◽  
pp. 204-210 ◽  
Author(s):  
Antoin D. de Weijer ◽  
Iris E.C. Sommer ◽  
Anne Lotte Meijering ◽  
Mirjam Bloemendaal ◽  
Sebastiaan F.W. Neggers ◽  
...  

2015 ◽  
Vol 30 (9) ◽  
pp. 1438-1443 ◽  
Author(s):  
Yu-Long Yang ◽  
Cheng Zhang ◽  
Gang Zhao ◽  
Ping Wu ◽  
Yue-Feng Ma ◽  
...  

2016 ◽  
Vol 21 (5) ◽  
pp. 795-803 ◽  
Author(s):  
M. van Beek ◽  
M. van Kleef ◽  
B. Linderoth ◽  
S.M.J. van Kuijk ◽  
W.M. Honig ◽  
...  

2015 ◽  
Vol 30 (suppl_3) ◽  
pp. iii239-iii239
Author(s):  
Konstantin Vishnevskii ◽  
Lyudmila Vinogradova ◽  
Alexander Zemchenkov ◽  
Alexei Smirnov

2020 ◽  
Vol 34 (1) ◽  
pp. 37-45
Author(s):  
Mu-N Liu ◽  
Heng-Liang Yeh ◽  
Ai Seon Kuan ◽  
Shih-Jen Tsai ◽  
Ying-Jay Liou ◽  
...  

Objective: Late-life depression (LLD) is a severe public health problem. Given that pharmacological treatments for LLD are limited by their side effects, development of efficient and tolerable nonpharmacological treatment for LLD is urgently required. This study investigated whether high-frequency external muscle stimulation could reduce depressive symptoms in LLD. Methods: Twenty-two older male veterans with major depression were recruited and randomized into a treatment (n = 9) or sham control group (n = 13). The groups received high-frequency external muscle stimulation or sham intervention 3 times per week for 12 weeks. Clinical symptoms and muscle strength were evaluated at baseline and every 2 weeks. Results: The 2 groups were homogeneous in age, baseline clinical symptoms, and muscle strength. The treatment group showed significant improvement in depression and anxiety scores and muscle strength (all P < .01), whereas the control group showed no significant change after the 12-week follow-up. Compared to the control group, the treatment group showed significant improvements in depression (Geriatric Depression Scale, P = .009; Hamilton Depression Rating Scale, P = .007) and anxiety scores (HAMA, P = .008) and muscle strength (all P < .001). Changes in depression and anxiety levels were significantly correlated with changes in muscle strength after the study. In the treatment group, we observed a trend of correlation between the reduction in depression and muscle strength gains. Conclusion: High-frequency external muscle stimulation appears to be an effective treatment for older patients with LLD. Large studies with more tests and/or conducted in different populations are warranted to validate these preliminary findings.


2012 ◽  
Author(s):  
Biagio Di Iorio ◽  
Serena Torraca ◽  
Pasquale Gustaferro ◽  
Gholamreza Fazeli ◽  
August Heidland

2021 ◽  
Vol 24 (3) ◽  
pp. 224
Author(s):  
De Carolis, G.

The sensorimotor diabetic polyneuropathy represents a serious health problem, as it is responsible for an increased risk of mortality and substantial morbidity, resulting from foot ulceration, amputations, and impaired quality of life. Appropriate drug treatments are often unsuccessful at providing adequate pain relief and the use of minimally invasive procedures such as spinal cord stimulation (SCS) represents a valid therapeutic choice. Patient’s medical history and characteristics as well as clinical indication for the procedure influence the clinician in choosing the right type of therapy. Here we describe two cases suffering from type 2 diabetes mellitus and sensorimotor polyneuropathy, refractory to conventional medical management: in both cases, the 10-kHz high-frequency SCS therapy led to a long-term clinically meaningful relief of symptomatology which was evaluated in terms of: complete discharge of analgesic drugs, significant reduction in the intensity of perceived pain, recovery of motor function, improvement of mood tone and sleep quality. KEY WORDS diabetic sensorimotor polyneuropathy; neuropathic pain; 10-kHz high-frequency spinal cord stimulation.


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