Production of aglycone protopanaxatriol from ginseng root extract using Dictyoglomus turgidum β-glycosidase that specifically hydrolyzes the xylose at the C-6 position and the glucose in protopanaxatriol-type ginsenosides

2013 ◽  
Vol 98 (8) ◽  
pp. 3659-3667 ◽  
Author(s):  
Hye-Ji Lee ◽  
Kyung-Chul Shin ◽  
Gi-Woong Lee ◽  
Deok-Kun Oh
Keyword(s):  
Ginseng Root ◽  
Root Extract ◽  
Dictyoglomus Turgidum

scholarly journals Reduced Self-Perception of Fatigue after Intake of Panax ginseng Root Extract (G115®) Formulated with Vitamins and Minerals—An Open-Label Study

2021 ◽  
Vol 18 (12) ◽  
pp. 6257
Author(s):  
Anne-Laure Tardy ◽  
Beatrice Bois De Fer ◽  
Salvador Cañigueral ◽  
David Kennedy ◽  
Andrew Scholey ◽  
...  
Keyword(s):  
Panax Ginseng ◽  
Daily Intake ◽  
Energy Performance ◽  
Ginseng Root ◽  
Root Extract ◽  
Physical Fatigue ◽  
Self Perception ◽  
Open Label ◽  
Open Label Study ◽  
Label Study

Background: Unexplained fatigue is a common complaint. When underlying disease causes have been eliminated, lifestyle measures and supplementation can be indicated. Elaborating on clinical findings that G115®, a dry extract from the root of Panax ginseng, combined with vitamins and minerals could alleviate fatigue, this open label study aimed at assessing its effect on perceived fatigue and energy. Methods: Healthy adults self-reporting fatigue (n = 103) completed the Multidimensional Fatigue Inventory questionnaire. They rated their perceptions of mental and physical fatigue, energy, performance, and stress at baseline and 15, 30, 60 and 90 days after a daily intake of 40 mg G115® formulated with vitamins and minerals. Results: Compared with baseline values, mean self-perception of general fatigue was reduced by −7.55 units [95% CI: −8.44; −6.66] (−41.8%, p < 0.0001) at 90 days. All assessed perception ratings (mental and physical fatigue, reduced activity and motivation, performance, and stress) were significantly and steadily improved from two weeks after supplementation up to study’s end. Overall satisfaction with the ability of the product to reduce fatigue reached 85% at Day 90. Conclusion: Daily intake with G115® extract formulated with vitamins and minerals suggests an improvement of self-perception of fatigue and energy in a fatigued adult population.

Biogenic silver and gold nanoparticles synthesized using red ginseng root extract, and their applications

2015 ◽  
pp. 1-6 ◽  
Author(s):  
Priyanka Singh ◽  
Yeon Ju Kim ◽  
Chao Wang ◽  
Ramya Mathiyalagan ◽  
Mohamed El-Agamy Farh ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Ginseng Root ◽  
Root Extract ◽  
Red Ginseng ◽  
Silver And Gold Nanoparticles

scholarly journals ANTIOXIDANT ACTIVITY AND TOTAL PHENOL AND FLAVONOIDS ANALYSIS OF SIBERIAN GINSENG ROOT

2020 ◽  
pp. 38-40
Author(s):  
NAGENDAR SHETTY ◽  
V. HARIKA ◽  
SUMITRA LOKRAS
Keyword(s):  
Antioxidant Activity ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Total Phenol ◽  
Ginseng Root ◽  
Root Extract ◽  
Frap Assay ◽  
Vitro Assay ◽  
Siberian Ginseng

Objective: This study was examined to in vitro antioxidant activity and Total Phenol and Flavonoids content analysis of methanolic root extract of Eleutherococcus senticosus (Siberian ginseng). Methods: 1,1-dephenyl-2-picryl-hydrazyl free radical scavenging and FRAP assay propose that antioxidant activity of methanol root extract because of reducing capacity of the antioxidant against oxidative effects of reactive oxygen species. Results: Scavenging activity of Siberian ginseng root RC50 value was shown 713.42±11.55 µg/ml and reducing power 0.13±0.01 mmol/g was investigated. In addition, total phenol 12.6±1.13 mg GAE/g DW and total flavonoids 9.8±0.20 mg QE/g DW were recorded. Conclusion: Although all tests were performed in vitro assay, these results recommend that Siberian ginseng root may be a good source of antioxidant ingrediant.

Neuroprotective effect of a ginseng (Panax ginseng) root extract on astrocytes primary culture

2007 ◽  
Vol 112 (2) ◽  
pp. 262-270 ◽  
Author(s):  
M.V. Naval ◽  
M.P. Gómez-Serranillos ◽  
M.E. Carretero ◽  
A.M. Villar
Keyword(s):  
Primary Culture ◽  
Panax Ginseng ◽  
Neuroprotective Effect ◽  
Ginseng Root ◽  
Root Extract

scholarly journals Ginsenoside-Rb1 Induces ARPE-19 Proliferation and Reduces VEGF Release

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Brandi S. Betts ◽  
Kalpana Parvathaneni ◽  
Bharat B. Yendluri ◽  
Jeffery Grigsby ◽  
Andrew T. C. Tsin
Keyword(s):  
Cell Proliferation ◽  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Ginseng Root ◽  
Root Extract ◽  
Ginsenoside Rb1 ◽  
Rpe Cells ◽  
Viable Cells ◽  
Age Related ◽  
Vegf Release

Rb1, a ginsenoside from ginseng root extract, possesses antiangiogenic effects, but its role on ocular cells has not been studied. We hypothesize that Rb1 inhibits the production of the angiogenic cytokine VEGF from ARPE-19 cells, leading to a significant reduction in the proliferation of ocular vasculatures. Data from our experiments show that Rb1 induced an increase in the number of ARPE cells in culture, while VEGF release (pg/10,000 viable cells) was significantly reduced. Treatment with VEGF and cotreatment with Rb1 and VEGF showed that this Rb1-induced cell proliferation was mediated by VEGF. Because VEGF from RPE plays a major role in promoting angiogenesis in ocular vasculatures. Our finding that Rb1 inhibits the release of VEGF from RPE cells suggests that Rb1 has a significant role in the eye to protect against angiogenic diseases such as age-related macular degeneration.

scholarly journals MASKULINISASI IKAN CUPANG (Betta sp.) MENGGUNAKAN EKSTRAK AKAR GINSENG (Panax sp.)

2018 ◽  
Vol 5 (1) ◽  
pp. 1-12
Author(s):  
Asrul . Ferdian ◽  
Muslim . ◽  
Mirna Fitrani
Keyword(s):  
Survival Rate ◽  
Panax Ginseng ◽  
Fish Larvae ◽  
Ginseng Root ◽  
Root Extract ◽  
Quality Of Water ◽  
Randomized Design ◽  
Completely Randomized Design

ABSTRACT The use of extract root ginseng in the process of Betta fish masculinization is expected to increase the testosterone. The purpose of this research is to determine the effect ginseng root extract to the percentage of the male betta fish by masculinization. This study has been conducted at the Basic Aquaculture Laboratory, Faculty of Agriculture, Sriwijaya University. This study use a completely randomized design with 4 treatments and 3 replications. The treatments in this research was betta fish larvae aged 7 days that submersed on ginseng root extract media with different concentration for 8 hours. The treatment were the addition of ginseng root extract as much as 1 mg/L (P1), 2 mg/L (P2), 3 mg/L (P3), 4 mg/L (P4) and without ginseng root extract addition as control (P0). Parameters observed consist of percentage of betta fish male, survival rate and quality of water. The result of this research shows that the addition of extract panax ginseng with difference concentration has significant effect to male betta fish percentage, but there is no a significant effect on survival rate. Treatment P3 with concentration 3 mg/L is the best result, it produced 95.05% of male betta fish after immersion for 8 hours. Keywords : Betta fish, Ginseng root extract, Immersion, Masculinization

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