VEGF-C Expression in Squamous Cell Carcinoma and Adenocarcinoma of the Esophagus

2007 ◽  
Vol 31 (9) ◽  
pp. 1768-1772 ◽  
Author(s):  
Christian Möbius ◽  
José Freire ◽  
Ingrid Becker ◽  
Marcus Feith ◽  
Björn L. D. M. Brücher ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Adenocarcinoma Of The Esophagus

Characteristics of growth factors levels in squamous cell carcinoma and adenocarcinoma of the esophagus.

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. e15511-e15511
Author(s):  
Elena Mikhaylovna Frantsiyants ◽  
Oleg Ivanovich Kit ◽  
Evgeniy N. Kolesnikov ◽  
Yulia A. Pogorelova ◽  
Natalia D. Cheryarina ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Growth Factors ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Adenocarcinoma Of The Esophagus

Sex steroids, sex-binding globulin, and prolactin in tissues of adenocarcinoma and esophageal squamous cell carcinoma.

2017 ◽  
Vol 35 (4_suppl) ◽  
pp. 79-79
Author(s):  
Oleg Ivanovich Kit ◽  
Elena Mikhaylovna Frantsiyants ◽  
Valeria Bandovkina ◽  
Evgeniy N. Kolesnikov ◽  
Roman E. Myagkov ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Sex Steroids ◽  
Tumor Biology ◽  
Free Testosterone ◽  
Adenocarcinoma Of The Esophagus ◽  
Esophageal Tumors ◽  
Hormonal Content ◽  
Resection Line

79 Background: Some researchers suggest that squamous cell carcinoma (SCC) and adenocarcinoma of the esophagus (ACE) are characterized by different pathogenesis, epidemiology and tumor biology, and therefore require different therapeutic strategies. The purpose of the study was to analyze local hormonal status in malignant esophageal tumors and surrounding tissues depending on the histogenesis. Methods: Levels of sex steroids – free testosterone (fT), estrone (E1), estriol (E3), prolactin (PRL) and sex steroid-binding globulin (SSBG) were studied by the standard ELISA methods in tumor tissue, perifocal zone and resection line of 39 patients aged 58-74 years: 27 SCC, 12 ACE, stage II, G2, pT1-2N1M0. Results: Differences were found in local hormonal content in all studied samples dependint on the tumor histotype. Levels of SSBG, PRL and E1 in ACE were higher than in SCC by 1.3, 3.3 and 1.4 times, respectively, while fT concentration was 2.4 times lower. Levels of PRL, E1 and E3 in perifocal zone of ACE compared to SCC were higher by 2.8, 3.3 and 3.1 times, and fT was 1.3 times lower. Resection line of ACE differed from that of SCC by higher tissue concentrations of SSBG – by 1.3 times, PRL – by 1.5 times, E1 – by 1.3 times, E3 – by 1.7 times and a lower level of fT – by 1.5 times. As a result, fT/E1 ratios in ACE and surrounding tissues were on average 3 times lower than in corresponding SCC samples. Conclusions: Levels of hormones in esophageal tumors and surrounding tissues depend on the histogenesis. ACE was characterized by hyperestrogenism in esophageal tissues along with a high prolactin concentration, while SCC – by hyperandrogenism with a low PRL level. Different pathogenesis of SCC and ACE was demonstrated by the fact that hormonal profile in both tumor and resection line depended on the tumor histology.

Preoperative Chemoradiotherapy for Squamous Cell Carcinoma and Adenocarcinoma of the Esophagus

CHEST Journal ◽  
2002 ◽  
Vol 122 (4) ◽  
pp. 1302-1308 ◽  
Author(s):  
Ferdinando De Vita ◽  
Natale Di Martino ◽  
Michele Orditura ◽  
Angelo Cosenza ◽  
Gennaro Galizia ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Preoperative Chemoradiotherapy ◽  
Adenocarcinoma Of The Esophagus

scholarly journals High frequency of simultaneous loss of p16 and p16β gene expression in squamous cell carcinoma of the esophagus but not in adenocarcinoma of the esophagus or stomach

Oncogene ◽  
1997 ◽  
Vol 15 (12) ◽  
pp. 1481-1488 ◽  
Author(s):  
Kazuhiko Hayashi ◽  
Ralf Metzger ◽  
Dennis Salonga ◽  
Kathleen Danenberg ◽  
Lawrence P Leichman ◽  
...  
Keyword(s):  
Gene Expression ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
High Frequency ◽  
Carcinoma Of The Esophagus ◽  
Adenocarcinoma Of The Esophagus ◽  
Simultaneous Loss

Risk of Squamous Cell Carcinoma and Adenocarcinoma of the Esophagus in Patients With Achalasia

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Rocco Maurizio Zagari ◽  
Giovanni Marasco ◽  
Valentina Tassi ◽  
Stefano Ferretti ◽  
Marialuisa Lugaresi ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Adenocarcinoma Of The Esophagus

Activity of Taxol in Patients With Squamous Cell Carcinoma and Adenocarcinoma of the Esophagus

1994 ◽  
Vol 86 (14) ◽  
pp. 1086-1091 ◽  
Author(s):  
J. A. Ajani ◽  
D. H. Ilson ◽  
K. Daugherty ◽  
R. Pazdur ◽  
P. M. Lynch ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Adenocarcinoma Of The Esophagus

Comparison of the Long-Term Outcomes of Endoscopic Resection for Superficial Squamous Cell Carcinoma and Adenocarcinoma of the Esophagus in Japan

2014 ◽  
Vol 109 (3) ◽  
pp. 348-356 ◽  
Author(s):  
Kenichiro Nakagawa ◽  
Tomoyuki Koike ◽  
Katsunori Iijima ◽  
Hirohiko Shinkai ◽  
Waku Hatta ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Endoscopic Resection ◽  
Squamous Cell ◽  
Long Term Outcomes ◽  
Adenocarcinoma Of The Esophagus
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