Polycaprolactone/chitosan core/shell nanofibrous mat fabricated by electrospinning process as carrier for rosuvastatin drug

2021 ◽  
Author(s):  
P. Yousefi ◽  
G. Dini ◽  
B. Movahedi ◽  
S. Vaezifar ◽  
M. Mehdikhani
Keyword(s):  
Electrospinning Process ◽  
Core Shell

Design of Coaxial Needleless Electrospinning Electrode with Respect to the Distribution of Electric Field

2014 ◽  
Vol 693 ◽  
pp. 394-399 ◽  
Author(s):  
Lucie Vysloužilová ◽  
Jan Valtera ◽  
Karel Pejchar ◽  
Jaroslav Beran ◽  
David Lukáš
Keyword(s):  
Free Surface ◽  
Electric Field ◽  
Electrostatic Field ◽  
Electric Energy ◽  
Electrospinning Process ◽  
Coaxial Electrospinning ◽  
Core Shell ◽  
Process Stability ◽  
Field Simulation ◽  
Sharp Edges

The paper is focused on the design of the electrode for needleless coaxial electrospinning. This method allows to produce core/shell nanofibers from the free surface of a polymeric two-layer. The geometry of the designed model of electrode was analyzed using the software Autodesk Simulation Multiphysics. The results of electrostatic field simulation indicate the sharp edges of the electrode as the source of high electric intensity. These sharp edges lead to the loss of the electric energy during the electrospinning process. Based on that, the new cylindrical geometry of the electrode was developed. The results of carried out experiments clearly demonstrate the enhancement of the electrospinning process stability.

scholarly journals Effect of Solution Miscibility on the Morphology of Coaxial Electrospun Cellulose Acetate Nanofibers

Polymers ◽  
2021 ◽  
Vol 13 (24) ◽  
pp. 4419
Author(s):  
Ke Yan ◽  
Yao Le ◽  
Hu Mengen ◽  
Li Zhongbo ◽  
Huang Zhulin
Keyword(s):  
Cellulose Acetate ◽  
Shell Structure ◽  
Partial Solution ◽  
Electrospinning Process ◽  
Core Shell ◽  
Electrospinning Technique ◽  
Product Morphology ◽  
The Core ◽  
Core Shell Structure ◽  
Structural Characterizations

Coaxial electrospinning (co-electrospinning) technique has greatly expanded the universality of fabricating core-shell polymer nanofibers. However, the effect of solution miscibility on the morphology of co-electrospun products remains unclear. Herein, different cellulose acetate (CA) solutions with high solution miscibility but distinctly different electrospinnability were used to survey the effect of solution miscibility on the co-electrospinning process. The structural characterizations show that co-electrospun products are composed of nanofibers with and without the core-shell structure. This indicates that partial solution mixing occurred during the co-electrospinning process instead of absolute no-mixing or complete mixing. Importantly, the solution miscibility also shows a significant influence on the product morphology. In particular, the transformation from nanofibers to microparticles was realized with the increase of core-to-shell flow ratio during the co-electrospinning of core electrosprayable CA/dimethylacetamide (DMAc) solution and shell electrospinnable CA/acetone-DMAc (2/1, v/v) solution. Results show that the solution miscibility exerts a significant effect on not only the formation of core-shell structure but also the product morphology. This work provides a new insight for the in-depth understanding of the co-electrospinning process.

Optimization of the Electrospinning Process for Core–Shell Fiber Preparation

2014 ◽  
Vol 4 (11) ◽  
pp. 973-980 ◽  
Author(s):  
Ying Li ◽  
Jian Liu ◽  
John R. de Bruyn ◽  
Wankei Wan
Keyword(s):  
Electrospinning Process ◽  
Core Shell

Preparation and Ammonia Sensing Properties of PANI-TSA/PA6 Core-Shell Nanofibers by Electrospinning

2011 ◽  
Vol 421 ◽  
pp. 23-26 ◽  
Author(s):  
Yi Jun Pan ◽  
Xian Jun Dong ◽  
Qu Fu Wei ◽  
Wei Min Hung ◽  
Chao Yu Lin ◽  
...  
Keyword(s):  
Sulfonic Acid ◽  
Composite Nanofibers ◽  
Electrospinning Process ◽  
Core Shell ◽  
Formic Acid Solution ◽  
Sensing Properties ◽  
Ammonia Sensing ◽  
Structure And Morphology ◽  
Toluene Sulfonic Acid ◽  
Good Potential

PANI-TSA/PA6 core-shell nanofibers were prepared via the electrospinning process with a PA6/formic acid solution and the chemical polymerization of PANI doped with p-toluene sulfonic acid (TSA) on the surface of the PA6 nanofibers. Their structure and morphology were examined by FE-SEM and FTIR and the fabrication mechanism and ammonia sensing properties of the PANI-TSA/PA6 nanofibers were also investigated. All the results showed that, composite nanofibers with PANI-TSA shell and PA6 core had been prepared successfully, which showed a good potential in ammonia sensitivity application.

Fabrication and characterization of continuous silver nanofiber/polyvinylpyrrolidone (AgNF/PVP) core–shell nanofibers using the coaxial electrospinning process

RSC Advances ◽  
2016 ◽  
Vol 6 (59) ◽  
pp. 54162-54168 ◽  
Author(s):  
Molla Bahiru Gebeyehu ◽  
Yu-Hao Chang ◽  
Angaw Kelemework Abay ◽  
Shao-Yen Chang ◽  
Jiunn-Yih Lee ◽  
...  
Keyword(s):  
Electrospinning Process ◽  
Coaxial Electrospinning ◽  
Core Shell ◽  
Electrospinning Method ◽  
Fabrication And Characterization

Core–shell silver nanofiber/polyvinylpyrrolidone (AgNF/PVP) nanofibers have been successfully fabricated via an efficient coaxial-spinneret electrospinning method with a vertical configuration using PVP and AgNO3 as precursor solutions.

A Method for Scale-Up of Grooved Nanofibers via Flat Off-Centered Core-Shell Structure Spinneret

2014 ◽  
Vol 989-994 ◽  
pp. 556-559 ◽  
Author(s):  
Hui Hui Wu ◽  
Xiao Hua Meng ◽  
Yong Chun Zeng
Keyword(s):  
Production Rate ◽  
Shell Structure ◽  
Flat Surface ◽  
Scale Up ◽  
Electrospinning Process ◽  
Core Shell ◽  
Core Needle ◽  
The Core ◽  
Core Shell Structure ◽  
Novel Design

An approach to the scale-up of grooved nanofibers via a flat off-centered core-shell structure spinneret has been developed in this study. The spinneret with a flat surface involves shell-holes and off-centered core-needles. The position of the core-needle in the hole and the electrospinning process do influence the formation and structure of the grooved nanofibers. The production rate of the core-shell nanofibers can be enhanced by increasing the hole and needle number of the spinneret. This novel design is expected to provide a promising method towards the massive production of grooved nanofibers.

Self-Assembled Core-Shell Fe3O4@SiO2 Nanoparticles with High Magnetic Sensitivity from Electrospun Fibers

2014 ◽  
Vol 1033-1034 ◽  
pp. 1068-1071
Author(s):  
Li Qiang Tian ◽  
Pei Pei Zhang
Keyword(s):  
Self Assembly ◽  
Cetyltrimethylammonium Bromide ◽  
Room Temperature ◽  
Electrospinning Process ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Practical Applications ◽  
Magnetic Sensitivity ◽  
Core Shell Nanoparticles ◽  
Superparamagnetic Properties

Nanofibers composed of the hydrophilic polymer polyvinylpyrrolidone K90 (PVP), cetyltrimethylammonium bromide (CTAB), tetraethyl orthosilicate (TEOS) and Fe3O4were fabricated using an electrospinning process. As a result of the templating and confinement properties of the nanfibers, silica coated magnetite (Fe3O4@SiO2) core-shell nanoparticles (NPs) with high magnetic sensitivity were spontaneously formed through molecular self-assembly when the fibers were added to 80% aqueous ethanol (PH=9.0). The typical saturation magnetization of the Fe3O4@SiO2composite particles is up to 43.8 emu/g, with superparamagnetic properties being observed at room temperature. Since the nanoparticles have high magnetic sensitivity and are preparedviaa facile and convenient strategy, they have much promise in a range of practical applications.

scholarly journals Characterization and Release Behavior of a Thiosemicarbazone from Electrospun Polyvinyl Alcohol Core-Shell Nanofibers

Polymers ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 1488
Author(s):  
Hossein Barani ◽  
Mohsen Khorashadizadeh ◽  
Alexander Haseloer ◽  
Axel Klein
Keyword(s):  
Polyvinyl Alcohol ◽  
Inhibitory Concentration ◽  
Diffusion Mechanism ◽  
Antibacterial Properties ◽  
Electrospinning Process ◽  
Attenuated Total Reflection ◽  
Core Shell ◽  
Fiber Mats ◽  
Best Fit ◽  
Chemical Integrity

Mats of polyvinyl alcohol (PVA) core–shell nanofibers were produced using coaxial electrospinning in the presence of a thiosemicarbazone (TSC) N4-(S)-1-phenylethyl)-2-(pyridin-2-yl-ethylidene)hydrazine-1-carbothioamide (HapyTSCmB). Monolithic fibers with 0% or 5% TSC and core–shell fibers with 10% TSC in the spinning solution were studied to compare stability and release rates. SEM showed the formation of uniform, bead-free, cylindrical, and smooth fibers. NMR spectroscopy and thermal analysis (TG/DTA) gave proof for the chemical integrity of the TSC in the fiber mats after the electrospinning process. Attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectroscopy showed no TSC on the surface of the PVA/TSC-PVA fibers confirming the core–shell character. The TSC release profiles of the fibers as studied using UV-vis absorption spectroscopy showed a slower release from the PVA/TSC-PVA core–shell structure compared with the monolithic PVA/TSC fibers as well as lower cumulative release percentage (17%). Out of several release models, the Korsmeyer–Peppas model gave the best fit to the experimental data. The main release phase can be described with a Fick-type diffusion mechanism. Antibacterial properties were tested against the Gram-positive Staphylococcus aureus bacterium and gave a minimal inhibitory concentration of 12.5 μg/mL. 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazoliumbromide (MTT)-based cytotoxicity experiments showed that the cell viability of fibroblast at different contents of TSC was slightly decreased from 1.5% up to 3.5% when compared to control cells.

scholarly journals Core-Shell PVA/PVP-FeOOH Nanofibers as a Potential Visible Light Responsive Drug Delivery System

2020 ◽  
Vol 850 ◽  
pp. 259-263
Author(s):  
Anna Šutka
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Visible Light ◽  
Drug Carrier ◽  
High Surface ◽  
Electrospinning Process ◽  
Core Shell ◽  
Triggered Release ◽  
Electrospinning Technique ◽  
Fiber Core

The high surface area per unit volume and core-shell configuration of electrospun nanofiber mat has a potential for drug delivery applications. Co-axial electrospinning technique resolves the limitation in the traditional transdermal drug delivery materials allowing to load a larger concentration of therapeutic agents per unit mass of the polymer. Encapsulating the drug in the fiber core provides protection and prolonged drug release. In the present study mats of core-shell PVA/PVP-FeOOH nanofibers were successfully formed by the coaxial electrospinning process for the first time. The visible light responsive FeOOH drug carrier material was incorporated in fiber core to provide non-invasive drug release on demand. The prepared materials posses visible light triggered release of organic methylene blue molecules.

A novel bifunctional thermo-sensitive poly(lactic acid)@poly(butylene succinate) core–shell fibrous separator prepared by a coaxial electrospinning route for safe lithium-ion batteries

2017 ◽  
Vol 5 (44) ◽  
pp. 23238-23242 ◽  
Author(s):  
Xiaoyu Jiang ◽  
Lifen Xiao ◽  
Xinping Ai ◽  
Hanxi Yang ◽  
Yuliang Cao
Keyword(s):  
Lactic Acid ◽  
Lithium Ion Batteries ◽  
Lithium Ion ◽  
Electrospinning Process ◽  
Poly Lactic Acid ◽  
Coaxial Electrospinning ◽  
Core Shell ◽  
Butylene Succinate ◽  
Thermally Induced

A thermally induced shutdown separator of PLA@PBS is successfully fabricated by a facile coaxial electrospinning process for safe lithium ion batteries.

Sign in / Sign up

Export Citation Format

Share Document