Expression and function of WNT4 involved in larvae development and limb regeneration in Portunus trituberculatus

2020 ◽  
Author(s):  
Zhiming Ren ◽  
Yuanyuan Fu ◽  
Lei Liu ◽  
Xiao Liu ◽  
Chunlin Wang
Keyword(s):  
Limb Regeneration ◽  
Portunus Trituberculatus ◽  
And Function ◽  
Larvae Development

Transcriptomic analysis of Portunus trituberculatus reveals a critical role for WNT4 and WNT signalling in limb regeneration

Gene ◽  
2018 ◽  
Vol 658 ◽  
pp. 113-122 ◽  
Author(s):  
Lei Liu ◽  
Yuanyuan Fu ◽  
Fang Zhu ◽  
Changkao Mu ◽  
Ronghua Li ◽  
...  
Keyword(s):  
Critical Role ◽  
Limb Regeneration ◽  
Wnt Signalling ◽  
Transcriptomic Analysis ◽  
Portunus Trituberculatus

From Limbs to Lungs: A Newt Perspective on Compensatory Lung Growth

Physiology ◽  
1999 ◽  
Vol 14 (6) ◽  
pp. 260-267 ◽  
Author(s):  
Kirk A. Gilbert ◽  
D. Eugene Rannels
Keyword(s):  
Compensatory Growth ◽  
Lung Resection ◽  
Limb Regeneration ◽  
Structure And Function ◽  
Molecular Pathways ◽  
Lung Growth ◽  
Compensatory Lung Growth ◽  
And Function ◽  
Partial Lung Resection ◽  
Insight Into

Partial lung resection initiates compensatory growth of remaining lobes to restore pulmonary structure and function. Mechanisms underlying this response are not well defined. This article considers molecular pathways involved in control of amphibian limb regeneration and tissue pattern formation for novel insight into the understanding of compensatory lung growth.

scholarly journals Expression and function of neural cell adhesion molecule during limb regeneration.

1986 ◽  
Vol 83 (21) ◽  
pp. 8395-8399 ◽  
Author(s):  
C. E. Maier ◽  
M. Watanabe ◽  
M. Singer ◽  
I. G. McQuarrie ◽  
J. Sunshine ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
Neural Cell Adhesion Molecule ◽  
Limb Regeneration ◽  
Neural Cell ◽  
Neural Cell Adhesion ◽  
And Function

Expression and function analysis of metallothionein in the testis of Portunus trituberculatus exposed to cadmium

2013 ◽  
Vol 140-141 ◽  
pp. 1-10 ◽  
Author(s):  
Dong-Fang Xiang ◽  
Jun-Quan Zhu ◽  
Shan Jin ◽  
Yan-Jun Hu ◽  
Fu-Qing Tan ◽  
...  
Keyword(s):  
Function Analysis ◽  
Portunus Trituberculatus ◽  
And Function

scholarly journals Midkine is a dual regulator of wound epidermis development and inflammation during the initiation of limb regeneration

eLife ◽  
2020 ◽  
Vol 9 ◽  
Author(s):  
Stephanie L Tsai ◽  
Clara Baselga-Garriga ◽  
Douglas A Melton
Keyword(s):  
Inflammatory Cytokine ◽  
Limb Regeneration ◽  
Survival Signal ◽  
Wound Epidermis ◽  
Early Injury ◽  
And Function ◽  
Dual Regulator ◽  
Early Wound ◽  
Anti Inflammatory Cytokine ◽  
Critical Survival

Formation of a specialized wound epidermis is required to initiate salamander limb regeneration. Yet little is known about the roles of the early wound epidermis during the initiation of regeneration and the mechanisms governing its development into the apical epithelial cap (AEC), a signaling structure necessary for outgrowth and patterning of the regenerate. Here, we elucidate the functions of the early wound epidermis, and further reveal midkine (mk) as a dual regulator of both AEC development and inflammation during the initiation of axolotl limb regeneration. Through loss- and gain-of-function experiments, we demonstrate that mk acts as both a critical survival signal to control the expansion and function of the early wound epidermis and an anti-inflammatory cytokine to resolve early injury-induced inflammation. Altogether, these findings unveil one of the first identified regulators of AEC development and provide fundamental insights into early wound epidermis function, development, and the initiation of limb regeneration.

Conformation of Ribosomes from Escherichia Coli

1974 ◽  
Vol 32 ◽  
pp. 210-211
Author(s):  
M. Boublik ◽  
W. Hellmann ◽  
F. Jenkins
Keyword(s):  
Binding Sites ◽  
Ribosomal Proteins ◽  
Fluorescent Dyes ◽  
Protein Biosynthesis ◽  
Three Dimensional ◽  
Spatial Arrangement ◽  
Dimensional Structure ◽  
Complete Understanding ◽  
And Function

The present knowledge of the three-dimensional structure of ribosomes is far too limited to enable a complete understanding of the various roles which ribosomes play in protein biosynthesis. The spatial arrangement of proteins and ribonuclec acids in ribosomes can be analysed in many ways. Determination of binding sites for individual proteins on ribonuclec acid and locations of the mutual positions of proteins on the ribosome using labeling with fluorescent dyes, cross-linking reagents, neutron-diffraction or antibodies against ribosomal proteins seem to be most successful approaches. Structure and function of ribosomes can be correlated be depleting the complete ribosomes of some proteins to the functionally inactive core and by subsequent partial reconstitution in order to regain active ribosomal particles.

Sign in / Sign up

Export Citation Format

Share Document