Chemical Priming with Salt and Urea Improves Germination and Seedling Growth of Black Cumin (Nigella sativa L.) under Osmotic Stress

Abstract The objective of the study was to determine the responsible factors for germination and early seedling growth due to salt toxicity or osmotic effect and to optimize the best priming treatment for these stress conditions. To study the effect of osmopriming and hydropriming on germination and seedling growth of black cumin (Nigella sativa L.) under salt stress conditions this experiment was conducted at Torbat-Heydariyeh University, Torbat, Iran. The treated seeds (control, hydropriming and ZnSO4) of black cumin were evaluated at germination and seedling growth for tolerance to salt (NaCl and Na2SO4) conditions at the same water potentials of 0.0, -0.3, -0.6, -0.9 and -1.2MPa. Electrical conductivity (EC) values of the NaCl solutions were 0.0, 6.5, 12.7, 18.4 and 23.5 dSm-1, respectively. Results showed that hydropriming increased germination and seedling growth under salt stress. Germination delayed in both solutions, having variable germination with different priming treatments. In NaCl treatment, germination percentage, root and shoot weight, shoot and root length were higher but mean germination time and abnormal germination percentage were lower than Na2SO4, at the same water potential. The root / shoot weight and R/S length enhanced with increase of osmotic potential in both NaCl and Na2SO4 solutions. NaCl had less inhibitor effect on seedling growth than the germination. It was concluded that inhibition of germination at the same water potential of NaCl and Na2SO4 resulted from salt toxicity rather than osmotic effect. The findings of this experiment can be useful and applied to achieve best germination and uniform emergence under field conditions for farmers of medicinal plants.

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Harpino-like protective peptides of black cumin seeds (Nigella sativa L.)

IX Congress of society physiologists of plants of Russia "Plant physiology is the basis for creating plants of the future" ◽

10.26907/978-5-00130-204-9-2019-375 ◽

2019 ◽

Author(s):

E.A. Rogozhin ◽

Keyword(s):

Nigella Sativa ◽

Black Cumin

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Optimisation of the Oil Extraction from Nigella sativa Seeds Using Response Surface Methodology

Revista de Chimie ◽

10.37358/rc.17.2.5447 ◽

2017 ◽

Vol 68 (2) ◽

pp. 331-336

Author(s):

Gabriela Isopencu ◽

Mirela Marfa ◽

Iuliana Jipa ◽

Marta Stroescu ◽

Anicuta Stoica Guzun ◽

...

Keyword(s):

Response Surface Methodology ◽

Response Surface ◽

Nigella Sativa ◽

Polynomial Equation ◽

Herbaceous Plant ◽

Box Behnken Design ◽

Pareto Analysis ◽

Black Cumin ◽

Mediterranean Countries ◽

Experimental Values

Nigella sativa, also known as black cumin, an annual herbaceous plant growing especially in Mediterranean countries, has recently gained considerable interest not only for its use as spice and condiment but also for its healthy properties of the fixed and essential oil and its potential as a biofuel. Nigella sativa seeds fixed oil, due to its high content in linoleic acid followed by oleic and palmitic acid, could be beneficial to human health. The objective of this study is to determine the optimum conditions for the solvent extraction of Nigella sativa seeds fixed oil using a three-level, three-factor Box-Behnken design (BBD) under response surface methodology (RSM). The obtained experimental data, fitted by a second-order polynomial equation were analysed by Pareto analysis of variance (ANOVA). From a total of 10 coefficients of the statistical model only 5 are important. The obtained experimental values agreed with the predicted ones.

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The protective effect of Nigella Sativa oil extract against neurotoxicity induced by Valproic acid

International Journal of Bioassays ◽

10.21746/ijbio.2017.9.2 ◽

2017 ◽

Vol 6 (9) ◽

pp. 5474 ◽

Cited By ~ 2

Author(s):

Basant Mahmoud Morsy ◽

Ghada Mohamed Safwat ◽

Doaa Ahmed Hussein ◽

Reem Mohamed Samy

Keyword(s):

Valproic Acid ◽

Nigella Sativa ◽

Liver Lipid ◽

Black Cumin ◽

Enzymatic Antioxidant ◽

Nigella Sativa Oil ◽

Active Chemical ◽

Oil Extract ◽

Liver Lipid Peroxidation

Nigella sativa (NS), commonly known as black cumin, has been used for medicinal purposes. Traditionally the seeds and its oil are used in several diseases. The greatest part of the remedial properties of this plant is due to the presence of thymoquinone (TQ) which is a major active chemical component of the essential oil. The current study performed to evaluate the effect of Nigella sativa Oil (NSO) extract on the neurotoxic and hepatotoxic potentials from Valproic acid (VPA) administration. Also we summarize recent findings emphasizing the role of main neurotoxic and hepatotoxic markers and oxidative stress in study’s case. Neurotoxicity was induced by VPA at dose of (500 mg/kg b.wt) by gastric intubation daily for 30 day. These rats received NSO extract was given orally at dose of (0.5 ml/kg b.wt) daily for 30 days after VPA administration. The current results revealed that NSO extract treatment ameliorated significantly the elevated levels of the neurotoxic and hepatotoxic biomarkers which elevated as a result to VPA administration. Moreover, NSO extract treatment ameliorated the non-enzymatic antioxidant, brain and liver lipid peroxidation (LPO) and glutathione (GSH) concentration and the enzymatic antioxidant, brain and liver catalase(CAT) activity.

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Therapeutic perspectives of the black cumin component thymoquinone: A review

Food & Function ◽

10.1039/d1fo00401h ◽

2021 ◽

Author(s):

Chandan Sarkar ◽

Sarmin Jamaddar ◽

Tawhida Islam ◽

Milon Mondal ◽

Muhammad Torequl Islam ◽

...

Keyword(s):

Therapeutic Potential ◽

Nigella Sativa ◽

Pharmacological Properties ◽

Black Cumin

The dietary phytochemical thymoquinone, obtained from the black and angular seeds of Nigella sativa, is a promising monoterpenoid hydrocarbons, which has been receiving massive attention for its therapeutic potential and pharmacological properties.

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Estimation of technical efficiency of black cumin (Nigella sativa L.) farming in northwest Ethiopia: a stochastic frontier approach

Journal of Economic Structures ◽

10.1186/s40008-020-00198-1 ◽

2020 ◽

Vol 9 (1) ◽

Author(s):

Abebe Birara Dessie ◽

Tadie Mirie Abate ◽

Betelhem Tsedalu Adane ◽

Tiru Tesfa ◽

Shegaw Getu

Keyword(s):

Technical Efficiency ◽

Nigella Sativa ◽

Stochastic Frontier ◽

Market Price ◽

Northwest Ethiopia ◽

Flowering Plant ◽

Yield Potential ◽

Stochastic Frontier Model ◽

Black Cumin ◽

The Mean

Abstract Ethiopia is one of the east African countries which produce and exports various spices to other countries. Black cumin (Nigella sativa L.) is an important stiff annual flowering plant which mainly grows by producers for its seeds. An increasing demand of black cumin seed and oil in local, national and international market for medicinal, consumption and commercial purpose makes the best alternative crop for small holder farmers in Ethiopia. In spite of its importance, not much has been done to improve its production and productivity in Ethiopia. Therefore, this research was designed to examining efficiency variations and factors influencing technical inefficiency levels of producers on black cumin production in northwest Ethiopia. Primary data were collected using a semi-structured questionnaire administered on 188 black cumin producers selected using systematic random sampling technique. Moreover, various data analysis methods such as descriptive statistics and stochastic frontier model were used for analyzing the data. The empirical result obtained by applying maximum likelihood estimate of stochastic frontier model revealed that seed (p < 0.01) labor (p < 0.05), chemical (p < 0.01) and land (p < 0.05) were significant input variables in determining black cumin production. The mean technical efficiency level of black cumin producer was generally low, about 53.1%. The mean value of actual yield, potential yield and yield gap was 3.131, 5.832 and 2.701 quintals, respectively. Moreover, the result of stochastic frontier model together with the inefficiency parameters revealed that market price of black cumin (p < 0.01) and access of extension service (p < 0.1) were significant variables and positively influenced the efficiency levels of black cumin producers. Whereas age of producers (p < 0.05) and distance to farm plot (p < 0.01) negatively influenced the technical efficiency levels of black cumin producers. Therefore, the study recommends that adoption of latest agricultural technologies; development of institutions, agricultural extension services and infrastructure are advisable to improve the efficiency and commercial value of black cumin production.

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Black Cumin (Nigella sativa L.): A Comprehensive Review on Phytochemistry, Health Benefits, Molecular Pharmacology, and Safety

Nutrients ◽

10.3390/nu13061784 ◽

2021 ◽

Vol 13 (6) ◽

pp. 1784

Author(s):

Md. Abdul Hannan ◽

Md. Ataur Rahman ◽

Abdullah Al Mamun Sohag ◽

Md. Jamal Uddin ◽

Raju Dash ◽

...

Keyword(s):

Nigella Sativa ◽

Health Benefits ◽

Underlying Mechanism ◽

Future Research ◽

Molecular Pharmacology ◽

Active Components ◽

Drug Induced ◽

Current Effort ◽

Black Cumin ◽

Pharmaceutical Industries

Mounting evidence support the potential benefits of functional foods or nutraceuticals for human health and diseases. Black cumin (Nigella sativa L.), a highly valued nutraceutical herb with a wide array of health benefits, has attracted growing interest from health-conscious individuals, the scientific community, and pharmaceutical industries. The pleiotropic pharmacological effects of black cumin, and its main bioactive component thymoquinone (TQ), have been manifested by their ability to attenuate oxidative stress and inflammation, and to promote immunity, cell survival, and energy metabolism, which underlie diverse health benefits, including protection against metabolic, cardiovascular, digestive, hepatic, renal, respiratory, reproductive, and neurological disorders, cancer, and so on. Furthermore, black cumin acts as an antidote, mitigating various toxicities and drug-induced side effects. Despite significant advances in pharmacological benefits, this miracle herb and its active components are still far from their clinical application. This review begins with highlighting the research trends in black cumin and revisiting phytochemical profiles. Subsequently, pharmacological attributes and health benefits of black cumin and TQ are critically reviewed. We overview molecular pharmacology to gain insight into the underlying mechanism of health benefits. Issues related to pharmacokinetic herb–drug interactions, drug delivery, and safety are also addressed. Identifying knowledge gaps, our current effort will direct future research to advance potential applications of black cumin and TQ in health and diseases.

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