Visceral fat area, not body mass index, predicts postoperative 30-day morbidity in patients undergoing colon resection for cancer

Abstract ObjectivesThis study examined the relationship between cognitive performance and obesity parameters, such as body mass index (BMI), visceral fat area (VFA), waist circumference (WC), and waist-to-hip ratio (WHR) in western China.Study designA cross-sectional studyMethods3914 participants, aged >50 years, were recruited in this study. Anthropometrics measurements, life-style factors, chronic disease comorbidities, and sleep qualities were recorded for each participant. Among the anthropometrics, BMP, WC, and WHR were assessed using standard procedures, while VHA was calculated using bioelectrical impedance analysis. Cognitive performance was estimated using the Short Portable Mental Status Questionnaire (SPMSQ). Finally, relationships between cognitive abilities and BMI, VFA, WC, and WHR were evaluated using univariate and multivariate regression analyses. ResultsCognitive decline (CD) occurred at a rate of 13.29% among the 3914 participants. A strong correlation was observed between cognitive abilities and BMI of male patients aged 50-59 yrs (OR 1.116,95% CI1.002-1.242), in the adjusted model. Alternately, WHR was shown to be significantly related to CD in females aged >70 years (OR 0.041, 95% CI0.002-0.671). WC was shown to have a strong association with CD in males (OR 1.023,95% CI1.003-1.024). Lastly, WHR was closely connected to CD in participants with BMI < 25 kg/m2 (OR 0.022,95% CI0.002-0.209).Conclusions Our findings suggest that a higher middle age BMI is associated with CD, whereas, in the elderly population, a higher WHR is related to improved cognitive performance. Further investigation is warranted to elucidate a relationship between VFA and CD.

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Value of Visceral Fat Area in the Preoperative Discrimination of Peritoneal Metastasis from Gastric Cancer in Patients with Different Body Mass Index: A Prospective Study

Cancer Management and Research ◽

10.2147/cmar.s257849 ◽

2020 ◽

Vol Volume 12 ◽

pp. 6523-6532

Author(s):

He Huang ◽

Xinxin Yang ◽

Jing Sun ◽

Ce Zhu ◽

Xiang Wang ◽

...

Keyword(s):

Gastric Cancer ◽

Body Mass Index ◽

Prospective Study ◽

Body Mass ◽

Peritoneal Metastasis ◽

Visceral Fat ◽

P Value ◽

Visceral Fat Area ◽

A Prospective Study

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Comment on: Visceral fat area as a new predictor of short-term diabetes remission after Roux-en-Y gastric bypass surgery in Chinese patients with a body mass index less than 35 kg/m2

Surgery for Obesity and Related Diseases ◽

10.1016/j.soard.2014.07.007 ◽

2015 ◽

Vol 11 (1) ◽

pp. 11-13

Author(s):

Ricardo Cohen

Keyword(s):

Body Mass Index ◽

Gastric Bypass ◽

Body Mass ◽

Visceral Fat ◽

Bypass Surgery ◽

Gastric Bypass Surgery ◽

Diabetes Remission ◽

Chinese Patients ◽

Short Term ◽

Visceral Fat Area

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Value of visceral fat area in normal body mass index (BMI) patients is a predictive factor for peritoneal metastasis in gastric cancer: A prospective study

10.21203/rs.3.rs-15896/v1 ◽

2020 ◽

Author(s):

Chenchen Mao ◽

Mingming Shi ◽

Hui Chen ◽

Libin Xu ◽

He Huang ◽

...

Keyword(s):

Risk Factors ◽

Gastric Cancer ◽

Body Mass Index ◽

Logistic Regression ◽

Body Mass ◽

Peritoneal Metastasis ◽

Visceral Fat ◽

Visceral Fat Area ◽

Cutoff Values ◽

High Bmi

Abstract Background Although peritoneal metastasis (PM) is associated with poor prognosis in gastric cancer (GC) patients, it is difficult to discriminate preoperatively. Our previous study has demonstrated visceral fat area (VFA) is a better obesity index than body mass index (BMI) in predicting abdominal metastasis. Aim This study aimed to further explore the relationship between obesity and PM. Methods VFA was retrieved for 859 consecutive patients undergoing radical gastrectomy between January 1, 2009 and December 31, 2013. A receiver operating characteristic curve analysis was used to determine the BMI-specific cutoff values for VFA. Univariate and multivariate analyses evaluating the risk factors for PM at different BMI levels were performed. Results The optimal cutoff values for VFA were 67.28, 88.03, and 175.32 cm 2 for low, normal, and high BMI patients, respectively, and 18 (15.52%), 220 (40.15%), and 61 (31.28%) patients were classified as having high VFA in each group. Univariate logistic regression revealed that the association between high VFA and PM was not dependent on BMI (odds ratio [OR]=9.048, P=0.007 for low BMI, OR=3.827, P<0.001 for normal BMI, and OR=2.460, P=0.049 for high BMI). In multivariate logistic regression analysis, high VFA (OR=3.816, P<0.001) and vascular invasion (OR=1.951, P=0.039) were independent risk factors for PM only in the normal BMI group. Conclusions VFA only effectively predicted PM for GC patients with normal BMI, rather than those with low and high BMI. More attentions should be paid to those GC patients with high VFA and normal BMI.

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Clinical significance of obesity index (VFA versus BMI) as a risk factor for gastric cancer surgery.

Journal of Clinical Oncology ◽

10.1200/jco.2012.30.4_suppl.139 ◽

2012 ◽

Vol 30 (4_suppl) ◽

pp. 139-139 ◽

Cited By ~ 1

Author(s):

Kyo Young Song ◽

Jung Ho Shim

Keyword(s):

Body Mass Index ◽

Risk Factor ◽

Body Mass ◽

Visceral Fat ◽

Visceral Fat Area ◽

Obesity Index ◽

Group A ◽

Low Bmi ◽

Male Patients ◽

Group B

139 Background: Obesity is considered as a major perioperative risk factor in various cancer surgeries. We aimed to elucidate the effect of two different obesity index, such as VFA (visceral fat area) and BMI (body mass index), on gastrectomy. Methods: From Mar 2009 to July 2010, 632 patients with diagnosed gastric carcinoma underwent curative gastrecomy at Seoul St. Mary’s hospital. We reviewed patients’ clinicopatholic data and collected 187 patients who had data including BMI, VFA and SFA. Patients with body mass index (BMI) ≥ 25 kg/m 2 were defined as obese and visceral fat area (VFA) ≥ 100 were defined as centrally obese. Results: Out of a total 187 patients, eighty patients were in the high BMI group and 107 patients were in the low BMI group. We selected patients with high VFA and low BMI (group A) and compared to the patients with low VFA and low BMI (group B). Out of a total 107 patients in low BMI, seventy three patients were censored as high VFA, and age older than 60 and male patients were prevalent in this group (p=0.045 and 0.046). The operation time (OT) and estimated blood loss (EBL) were significantly higher in group A than group B (p=0.043 and p=0.05). Conclusions: VFA and BMI are correlated each other and successfully represent patients’ obesity. However in selected patients, such as male patients with age older than sixty, VFA more practically represent their obesity.

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Abdominal Visceral Fat Area and Chronic Pouchitis after Ileal Pouch-Anal Anastomosis

The American Surgeon ◽

10.1177/000313481708301003 ◽

2017 ◽

Vol 83 (10) ◽

pp. 1029-1032 ◽

Cited By ~ 1

Author(s):

Vivek Pandrangi ◽

Daniel Mandel ◽

Norman Gellada ◽

Cindy Kallman ◽

Karen Zaghiyan ◽

...

Keyword(s):

Body Mass Index ◽

Body Mass ◽

Visceral Fat ◽

Ileal Pouch ◽

Ileal Pouch Anal Anastomosis ◽

Study Cohort ◽

Refractory Disease ◽

Visceral Fat Area ◽

Anal Anastomosis ◽

Abdominal Visceral Fat

Chronic pouchitis (CP) after ileal pouch-anal anastomosis is a significant clinical problem. Adipose tissues produce antiinflammatory cytokines and chemokines. We evaluated the association between abdominal visceral fat area (VFA) and CP. Patients with a preoperative CT evaluation were included. The diagnosis of CP was confirmed in all cases by endoscopy with afferent ileal limb intubation. Patients were allocated into groups of high VFA and low VFA. The study cohort of 52 patients had a median body mass index of 22 (range, 14–32). Indications for surgery were medically refractory disease in 46 (88%) patients and cancer/dysplasia in six (12%) patients. Median VFA was 27.1 (range, 1–144). Six (12%) patients developed CP. Low VFA patients were significantly younger (29 vs 45 years; P < 0.0001), had lower body mass index (20.4 vs 24.7; P < 0.0001), had surgery more commonly for medically refractory disease than for cancer or dysplasia (100 vs 77%; P = 0.02), and had a higher incidence of CP than high VFA patients (23 vs 0%; P = 0.02). Multiple linear regression analysis demonstrated that only low VFA was associated with CP (P = 0.009). An association is present between VFA and CP after ileal pouch-anal anastomosis, implicating adipocytes in the pathogenesis of inflammatory bowel disease.

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Association between Nutrients and Visceral Fat in Healthy Japanese Adults: A 2-Year Longitudinal Study Brief Title: Micronutrients Associated with Visceral Fat Accumulation

Nutrients ◽

10.3390/nu11112698 ◽

2019 ◽

Vol 11 (11) ◽

pp. 2698 ◽

Cited By ~ 1

Author(s):

Ozato ◽

Saito ◽

Yamaguchi ◽

Katashima ◽

Tokuda ◽

...

Keyword(s):

Body Mass Index ◽

Longitudinal Study ◽

Waist Circumference ◽

Dietary Fiber ◽

Body Mass ◽

Visceral Fat ◽

Dietary Habits ◽

Pantothenic Acid ◽

Monounsaturated Fat ◽

Visceral Fat Area

: High visceral fat area (VFA) is a stronger predictor of cardiovascular disease and overall mortality than body mass index or waist circumference. VFA may be decreased by proper dietary habits. Although previous epidemiologic studies demonstrated an association between nutritional components or foodstuffs and VFA, only the associations of a few nutrients, such as dietary fiber and calcium, are reported. We performed a comprehensive 2-year longitudinal study in more than 624 healthy people and analyzed 33 micronutrients to investigate nutrients that contribute to changes in visceral fat. Our analyses revealed that “macronutrients” and “micronutrients” were “mutual confounders”. Therefore, when evaluating the association between VFA and micronutrients, associations were adjusted by macronutrients. The ingestion of 7 nutrients: soluble dietary fiber, manganese, potassium, magnesium, vitamin K, folic acid, and pantothenic acid, which are abundant components in vegetable diets, was significantly inversely correlated with a change in VFA. Additionally, a change in the ingestion of one nutrient, monounsaturated fat, was significantly positively correlated with a change in VFA. These associations were independent of body mass index and waist circumference. Thus, a predominantly vegetable diet may decrease VFA. In addition, adjusting the intake of macronutrients might help to clarify the association of micronutrients with VFA.

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