Elevated diastolic blood pressure in insulin-resistant polycystic ovarian syndrome patients

2013 ◽  
Vol 289 (1) ◽  
pp. 119-122 ◽  
Author(s):  
Angélica Maria Holanda Pascoal da Silva ◽  
Ana Carolina Rodrigues de Andrade ◽  
Bruno Hállan Meneses Dias ◽  
Maria Angelina da Silva Medeiros ◽  
Vietla Satianarayana Rao ◽  
...  
2021 ◽  
Vol 13 (2) ◽  
pp. 1-08
Author(s):  
Jeyshree Krishnaswamy Sundararajan ◽  
Yanyan Li ◽  
Ahmad Hadaegh

Polycystic ovarian syndrome(PCOS) is one of the predominant hormonal imbalances present in women of reproductive age. It needs to be diagnosed and treated at an earlier stage as it's inter-related to diabetes, high cholesterol levels, and obesity. This paper presents an application specially designed for women to help them keep track of their Body Mass Index, Blood Sugar, and Blood Pressure based on their age. The people diagnosed with PCOS(an endocrine disorder) can use this application to make their life easy since it helps follow certain exercises, diets, and timely reminders for water and medicines. It has features like the period tracker to track the user’s menstrual cycle, find dieticians nearby, links to various PCOS supplements, users can track their moods during different menstrual phases and control their mood swings. Finally, the application has games to add that interactive touch.


2011 ◽  
Vol 96 (11) ◽  
pp. 3533-3540 ◽  
Author(s):  
Nina Lass ◽  
Michaela Kleber ◽  
Katrin Winkel ◽  
Rainer Wunsch ◽  
Thomas Reinehr

Abstract Context: Polycystic ovarian syndrome (PCOS) is associated with cardiovascular risk factors (CRF). Lifestyle intervention is regarded as therapy of choice even if studies in adolescent girls with PCOS are scarce. Objective: Our objective was to analyze the impact of lifestyle intervention on menses irregularities, hyperandrogenemia, CRF, and intima-media thickness (IMT) in adolescent girls with PCOS. Patients: Patients included 59 obese girls with PCOS aged 12–18 yr. Intervention: Intervention was a 1-yr lifestyle intervention based on nutrition education, exercise training, and behavior therapy. Main Outcome Measures: Menses cycles, IMT, waist circumference, blood pressure, fasting lipids, insulin, glucose, testosterone, dehydroepiandrosterone sulfate, androstenedione, and SHBG were evaluated. Results: In contrast to the 33 girls without weight loss, the 26 girls reducing their body mass index during the lifestyle intervention (by a mean of −3.9 kg/m2) improved most CRF and decreased their IMT (by a mean of −0.01 cm). Testosterone concentrations decreased (by a mean of −0.3 nmol/liter) and SHBG concentrations increased (by a mean of +8 ng/ml) significantly in girls with weight loss in contrast to girls with increasing weight. The prevalence of amenorrhea (−42%) and oligoamenorrhea (−19%) decreased in the girls with weight loss. The changes in insulin in the 1-yr follow-up were significantly correlated to changes in testosterone (r = 0.38; P = 0.002) and SHBG (r = −0.35; P = 0.048). A linear regression model with changes in IMT as dependent variable demonstrated a significant association with changes in blood pressure and weight status but not with changes in testosterone. Conclusions: Weight loss due to lifestyle intervention is effective to treat menses irregularities, normalize androgens, and improve CRF and IMT in obese adolescent girls with PCOS.


Author(s):  
Urooj Zafar ◽  
Aliya Irshad Sani ◽  
Hira Ahmed Malik ◽  
Aisha Faraz ◽  
Rabeea Rizwan ◽  
...  

Background: Polycystic ovarian syndrome (PCOS) is a hormonal disorder common among women of the child-bearing age. Likewise, women with PCOS are more likely to be obese or overweight, which may be due to their higher Insulin resistance and TSH levels. Aim: The study's objectives were to assess the prevalence of subclinical hypothyroidism in infertile PCOS, distribution of insulin resistant in PCOS women with subclinical hypothyroidism, and the efficacy of Metformin treatment in these women. Methods: It was a single-center study which included all infertile patients who visited the Department of Obstetrics and Gynecology at a Karachi hospital between January 2019 and September 2019. The infertile PCOS patients were then divided into two groups: Group A (Insulin Resistant with Subclinical Hypothyroidism) and Group B. (Non-Insulin Resistant with Subclinical Hypothyroidism). Following the written consent, both the treatment groups received Metformin 500mg T.D. for three months. Results: The infertile PCOS patients showed a higher prevalence of subclinical hypothyroidism. Insulin resistance was found to be 63.3% among subclinical hypothyroid PCOS women. Finally, three months of Metformin treatment resulted in a significant reduction in TSH levels in Insulin resistant PCOS women. Conclusion: We identified a positive link between TSH levels and insulin resistance in PCOS women, both in terms of incidence and treatment.


Sign in / Sign up

Export Citation Format

Share Document