Possible role of Chlamydia trachomatis in the male partner of infertile couples

2012 ◽  
Vol 22 (3) ◽  
pp. 421-424 ◽  
Author(s):  
Zahra Noruziyan ◽  
Rasoul Roghanian ◽  
Saeid Hosseinzadeh ◽  
Nasser Golbang ◽  
Mohammad Hossein Nasr Esfahani
Keyword(s):  
Chlamydia Trachomatis ◽  
Male Partner ◽  
Infertile Couples

scholarly journals Role of Ayurvediya Chikitsa in management of primary infertility: A case study

2017 ◽  
Vol 5 (5) ◽  
Author(s):  
Achana Jadhav ◽  
Abhay Kuikarni ◽  
Gitanjali Vaidya
Keyword(s):  
Internal Medicine ◽  
Menstrual Cycle ◽  
Life Style ◽  
Male Partner ◽  
Female Partner ◽  
Ovulatory Dysfunction ◽  
Infertile Couples ◽  
Present Case Study

Infertility is major disorder due to stressful world, lack of biological food, changing life style. Four essential factors for conception mentioned by ancient ayurveda scholar sushruta are as imperative today as they were ovum is one among these essential factors, vitiation of vata reflects ovulatory  dysfunction. most of  infertile couples have multiple causes contributing infertility. In the present case study female partner had pcos and male partner is normal resulting in infertility. She had regular but scanty menses with severe dysmenorrhea. According to ayurveda  apanvayu  governs all  functions related to garbhashaya and menstrual cycle. Considering infertility, pcos  and  tivra apan vayu dushti as yonivyapada she was treated with basti for vatshamana , phala ghrit  utterbasti  for  garbhashaya dushti   and internal medicine like chandraprabha vati, ampachak vati , sukumar kashay, kuberaksh vati , phala ghrit, lashunadi vati, laghumalini vasant  for deepan pachan and pcos.and dashmularishta for vata pacification.

scholarly journals Chlamydia trachomatis and urogenital mycoplasms in nonconococcal urethirits in men

2010 ◽  
Vol 63 (1-2) ◽  
pp. 47-50
Author(s):  
Sonja Vesic ◽  
Jelica Vukicevic ◽  
Eleonora Gvozdenovic ◽  
Dusan Skiljevic ◽  
Slobodanka Janosevic ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Ureaplasma Urealyticum ◽  
Mycoplasma Hominis ◽  
Sexually Active ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
Nongonococcal Urethritis ◽  
Etiological Agents ◽  
The One

Introduction. Nongonococcal urethritis is the most common sexually transmitted infection in men, with vast majority of the etiological agents such as Chlamydia trachomatis, followed by urogenital mycoplasmas. The aim of this study was to determine the prevalence of Chlamydia trachomatis, Ureaplasma urealyticum and Mycoplasma hominis in nongonococcal urethritis in men, and to examine infections associated with these agents. Material and methods. 299 sexually active, heterosexual men with nongonococcal urethritis were included into the study. Urethral samples were taken with a dacron swab placed into the urethra up to 2-3 cm. The Direct immunojluorescence tehnique was performed for identification of Chlamydia trachomatis. Ureaplasma urealyticum and Mycoplasma hominis were detected with Mycoplasma 1ST assay. Results. Chlamydia trachomatis was detected in 22.75%, Uraeplasma urealyticum in 21.08% and Mycoplasma hominis in 8.02% cases. We found no significant differences in prevalence between Chlamydia trachomatis and Ureaplasma urealyticym (p>0.05). Monoinjections were found in 51.85% with significantly higher rate (p<0.01) than associated infections (11.70%). Among associated infections, coinfection of Chlamydia trahomatis and Ureaplasma urealyticum was predominant. Association of Chlamydia trachomatis with urogenital mycoplasmas was significantly higher (p<0.05) than the one between Ureaplasma urealyticum and Mycoplasma hominis. In 36.45% patients no patogenic microorganisms were detected. Conclusion. These results confirmed the etiological role of Chlamydia trachomatis and urogenital mycoplasmas in nongonococcal urethritis with prevalence of 51.85% in monoinfections and 11.70% in associated infections. In 36.45% of cases the etiology of urethritis was not elucidated. These results suggest that more sensitive diagnostic tool should be applied when searching for the detailed etiology of nongonococcal urethritis.

The role of Chlamydia trachomatis in prostatitis

2002 ◽  
Vol 19 (6) ◽  
pp. 466-470 ◽  
Author(s):  
W. Weidner ◽  
Th. Diemer ◽  
P. Huwe ◽  
H. Rainer ◽  
M. Ludwig
Keyword(s):  
Chlamydia Trachomatis

Evidence for cGAS-STING signaling in the female genital tract resistance to Chlamydia trachomatis infection

2022 ◽  
Author(s):  
Xin Su ◽  
Hong Xu ◽  
Maegan French ◽  
Yujie Zhao ◽  
Lingli Tang ◽  
...  
Keyword(s):  
Innate Immunity ◽  
Chlamydia Trachomatis ◽  
Signaling Pathway ◽  
Genital Tract ◽  
Essential Role ◽  
Cultured Cells ◽  
Female Genital Tract ◽  
Lower Genital Tract ◽  
Female Genital

Sexually transmitted Chlamydia trachomatis can ascend to the upper genital tract due to its resistance to innate immunity in the lower genital tract. C. trachomatis can activate cGAS-STING signaling pathway in cultured cells via either cGAS or STING. The current study was designed to evaluate the role of the cGAS-STING pathway in innate immunity against C. trachomatis in the mouse genital tract. Following intravaginal inoculation, C. trachomatis significantly declined by day 5 following a peak infection on day 3 while the mouse-adapted C. muridarum continued to rise for >1 week, indicating that C. trachomatis is susceptible to the innate immunity in the female mouse genital tract. This conclusion was supported by the observation of a similar shedding course in mice deficient in adaptive immunity. Thus, C. trachomatis can be used to evaluate innate immunity in the female genital tract. It was found that mice deficient in either cGAS or STING significantly increased the yields of live C. trachomatis on day 5, indicating an essential role of the cGAS-STING signaling pathway in innate immunity of the mouse genital tract. Comparison of live C. trachomatis recovered from different genital tissues revealed that the cGAS-STING-dependent immunity against C. trachomatis was restricted to the mouse lower genital tract regardless of whether C. trachomatis was inoculated intravaginally or transcervically. Thus, we have demonstrated an essential role of the cGAS-STING signaling pathway in innate immunity against chlamydial infection, laying a foundation for further illuminating the mechanisms of the innate immunity in the female lower genital tract.

scholarly journals Chlamydia trachomatis infection: a challenge for the urologist

2011 ◽  
Vol 2 (1) ◽  
pp. 14 ◽  
Author(s):  
Tommaso Cai ◽  
Sandra Mazzoli ◽  
Nicola Mondaini ◽  
Gianni Malossini ◽  
Riccardo Bartoletti
Keyword(s):  
Chlamydia Trachomatis ◽  
Bacterial Infections ◽  
Reproductive Tract ◽  
Diagnosis And Treatment ◽  
Everyday Clinical Practice ◽  
Chlamydia Trachomatis Infection ◽  
Sexually Transmitted ◽  
New Findings ◽  
Asymptomatic Infections

<p>The role of <em>Chlamydia trachomatis</em> (Ct) in everyday clinical practice is now on the increase because Ct infections are the most prevalent sexually transmitted bacterial infections worldwide. Ct can cause urethritis, cervicitis, pharyngitis, or epididymitis, although asymptomatic infections are quite common. Ct infection remains asymptomatic in approximately 50% of infected men and 70% of infected women, with risk for reproductive tract sequelae both in women and men. A proper early diagnosis and treatment is essential in order to prevent persistent consequences. An accurate comprehension of the pathology, diagnosis and treatment of this entity is essential for the urologist. We review the literature about the new findings in diagnosis and treatment of Ct infection in sexually active young men.</p>

scholarly journals Role of Kisspeptin in Puberty in Humans

2020 ◽  
pp. 92-97
Author(s):  
Ravi Kant ◽  
Mahendra Kumar Meena
Keyword(s):  
Reproductive Biology ◽  
Conventional Treatment ◽  
Hypogonadotropic Hypogonadism ◽  
Follicle Stimulating Hormone ◽  
Gonadotropin Releasing Hormone ◽  
Pilot Studies ◽  
Releasing Hormone ◽  
Infertile Couples ◽  
Stimulating Hormone

Kisspeptin or GPR-54 is a product of KISS 1 gene regulating the production of gonadotropin releasing hormone (GnRH), luteinizing (LH) as well follicle stimulating hormone (FSH). Both LH and FSH are important hormones for reproduction in animals as well in humans. The recognition of Kisspeptin has a landmark bearing in reproductive biology. Few recent pilot studies have convincingly proven it to be a promising molecule in treating infertile couples especially those having hypogonadotropic hypogonadism not responding to conventional treatment.

Urethral inflammatory response to ureaplasma is significantly lower than to Mycoplasma genitalium and Chlamydia trachomatis

2016 ◽  
Vol 28 (8) ◽  
pp. 773-780 ◽  
Author(s):  
Harald Moi ◽  
Nils Reinton ◽  
Ivana Randjelovic ◽  
Elina J Reponen ◽  
Line Syvertsen ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Inflammatory Response ◽  
Ureaplasma Urealyticum ◽  
Mycoplasma Genitalium ◽  
Nucleic Acid Amplification ◽  
Rrna Gene ◽  
Polymorphonuclear Leucocytes ◽  
Male Patients ◽  
Micro Organisms

A non-syndromic approach to treatment of people with non-gonococcal urethritis (NGU) requires identification of pathogens and understanding of the role of those pathogens in causing disease. The most commonly detected and isolated micro-organisms in the male urethral tract are bacteria belonging to the family of Mycoplasmataceae, in particular Ureaplasma urealyticum and Ureaplasma parvum. To better understand the role of these Ureaplasma species in NGU, we have performed a prospective analysis of male patients voluntarily attending a drop in STI clinic in Oslo. Of 362 male patients who were tested for NGU using microscopy of urethral smears, we found the following sexually transmissible micro-organisms: 16% Chlamydia trachomatis, 5% Mycoplasma genitalium, 14% U. urealyticum, 14% U. parvum and 5% Mycoplasma hominis. We found a high concordance in detecting in turn U. urealyticum and U. parvum using 16s rRNA gene and ureD gene as targets for nucleic acid amplification testing (NAAT). Whilst there was a strong association between microscopic signs of NGU and C. trachomatis infection, association of M. genitalium and U. urealyticum infections in turn were found only in patients with severe NGU (>30 polymorphonuclear leucocytes, PMNL/high powered fields, HPF). U. parvum was found to colonise a high percentage of patients with no or mild signs of NGU (0–9 PMNL/HPF). We conclude that urethral inflammatory response to ureaplasmas is less severe than to C. trachomatis and M. genitalium in most patients and that testing and treatment of ureaplasma-positive patients should only be considered when other STIs have been ruled out.

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