scholarly journals Long-term sero-positivity for IgG, sequelae of respiratory symptoms, and abundance of malformed sperms in a patient recovered from severe COVID-19

Author(s):  
Mingchao Zhu ◽  
Diliang Chen ◽  
Ya Zhu ◽  
Xusheng Xiong ◽  
Yan Ding ◽  
...  

AbstractPatients with severe coronavirus disease in 2019 (COVID-19 pneumonia) may have many sequelae, which seriously affect their quality of life and work. Here, we report a case of infection in China, reviewed the course, treatment, and rehabilitation of a patient suffering from severe COVID-19 pneumonia, and collected his examination reports, including chest CT, laboratory examination results, lung function examination, sleep monitoring report, sex hormones, sperm morphology and activity. The patient’s antiviral immunoglobulin G (IgG) continued to be positive for more than 11 months, and his small airway function was abnormal, and he suffered from respiratory problems (cough, chest pain, chest tightness, and shortness of breath), unstructured sleep apnea hypopnea syndrome, and nocturnal sleep hypoxemia. His abnormal sperm rate increased obviously, and sperm activity decreased obviously. Patients with severe COVID-19 pneumonia may have respiratory sequela, the abnormal sperm rate is obviously increased, and IgG positive can last for a long time.

2019 ◽  
Vol 32 (Supplement_1) ◽  
Author(s):  
F Bevilacqua ◽  
B Ragni ◽  
A Conforti ◽  
F Morini ◽  
A Dotta ◽  
...  

Abstract Background With improvements in surgical care long-term morbidity of patients with esophageal atresia (EA) has been recently taken into account (Lees et al., 2018). Morbidities include gastrointestinal and respiratory complication, problems of nutrition and growth, feeding difficulties, oral aversion or food refusal (Menzies et al., 2016). Aim Purpose of this study is to explore eating problems and its implications at 3 years in infants born with esophageal atresia. Methods A retrospective study including all infants operated for EA at our Institution in the period ranging from January 2012 and January 2016 who attended our follow-up program. A specific interview was set up for the study. The interview was delivered by telephone by a trained psychologist. Results Parents of 51 children (male = 67%) were interviewed. Twenty-two percent of children showed a growth <10th percentile; 30% presented oral aversion for a period of their life; 45% still have episodes of chock during meals and 18% of these had more than one episode a week; 45% suffer of GERD and 41% experienced recurrent respiratory problems; 37% of parents experience anxiety during meals. Fifty-seven percent attended kindergarten (8% with a dedicated educator during meal time), and 92% attended preschool (26% with dedicated educator during meal time). Currently 67% of the families benefit of social facilities. Conclusions Three years after surgical repair of the structural defect, a high percentage of family still experience physical and psychological problems related to eating behavior of their children. Efforts of the health care team as well as research should focus on how to prevent eating problems and improve quality of life both of children and families.


2020 ◽  
Vol 100 (1) ◽  
pp. 19-25
Author(s):  
Sarina K. Mueller ◽  
Maximilian Traxdorf ◽  
Konstantinos Mantsopoulos ◽  
Antoniu-Oreste Gostian ◽  
Matti Sievert ◽  
...  

Introduction: During the COVID-19 pandemic, worldwide over 600,000 human beings died due to the cause of the disease. In order to deescalate the transmission rate and to avoid crush loading the countries medical health systems social distancing, face masks, and lockdowns have been considered essential by the majority of governments. Whereas some countries have highly reduced or completely stopped otorhinolaryngological procedures, other countries have continued selected surgeries. The objective of this study was to analyze procedures and outcomes of continuing semielective and emergency surgeries during the COVID-19 pandemic. Methods: Retrospective analysis of n = 750 patients who received semi-elective or emergency surgery between March 26 and June 16, 2020, in the Otolaryngology Department of the Friedrich-Alexander-University of Erlangen-Nürnberg. All patients were screened for COVID symptoms and swabbed for SARS-CoV-2 prior to surgery. Results: Of the n = 750 patients, n = 699 patients received semielective surgery and n = 51 emergency surgery. For 27 patients, the swab result could not be awaited due to a life-threatening condition. In these cases, surgery was performed in full protective equipment. No patient was tested positive during or after the surgery (follow-up 45 to 127 days). No member of the medical personnel showed symptoms or was tested positive after contact with patients. Due to the continuation of surgeries, patients’ lives were saved and improvement of long-term quality-of-life and outcomes is anticipated. Conclusions: Continuing selected otorhinolaryngological surgeries is crucial for patients’ health, survival, and long-time quality of life, yet, the protection of the medical personnel has to be granted.


2019 ◽  
Vol 6 (1) ◽  
pp. 68-73
Author(s):  
Andrye Fernandes

Chemotherapy has an effect on the occurrence of sleep disorders in children who suffer from acute lymphoblastic leukemia. Sleep disorders experienced by children have an impact on optimizing the long-term quality of life of children. This study aims to describe sleep problems that occur in children suffering from acute lymphoblastic leukemia who undergo induction phase chemotherapy. The design of this study was descriptive analytic with repeated measurements of sleep disorders in children aged 7-18 years (n = 62). Data collection was carried out for 7 days, that is, one day before, five days during, and one day after chemotherapy. The results of data analysis found that children have > 15 minutes to fall asleep, children have less than normal amounts of sleep (the number of hours of sleep is normal, school age: 9-11 hours / day, adolescence: 8-10 hours / day) and there was a decrease in the quality of sleep scores. In conclusion, there are sleep disorders that occur in children, namely children have less time to sleep, children need a long time to be able to fall asleep, and children experience a decrease in the quality of sleep. The need for exploration of interventions to facilitate efficient sleep according to the stages of child development.


Author(s):  
Christina Lemhöfer ◽  
Christian Sturm ◽  
Dana Loudovici-Krug ◽  
Norman Best ◽  
Christoph Gutenbrunner

Abstract Background In COVID-19 survivors a relatively high number of long-term symptoms have been observed. Besides impact on quality of life, these symptoms (now called Post-COVID-Syndrome) may have an impact on functioning and may also hinder to participation in social life in affected people. However, little is known about developing such syndrome a for patients with mild and moderate COVID-19 who did not need hospitalization or intensive care. Methods A cross-sectional study in 1027 patients with mild or moderate COVID-19 was performed in two communities in Bavaria, Germany. The Rehabilitation-Needs-Survey (RehabNeS) including the Short Form 36 Health Survey (SF-36) on health-related quality of life, was used. Descriptive statistics were calculated. Results In all, 97.5% of patients reported one symptom in the infection stage, such as fatigue, respiratory problems, limitations of the senses of taste and smell, fear and anxiety and other symptoms. In this time period, 84.1% of the participants experienced activity limitations and participation restrictions such as carrying out daily routines, handling stress, getting household tasks done, caring for/supporting others, and relaxing and leisure concerns. In all, 61.9% of participants reported persisting symptoms more than 3 months after infection. These were fatigue, sleep disturbances, respiratory problems, pain, fear and anxiety, and restrictions in movement; 49% of the participants reported activity limitations and participation restrictions. Predominately, these were handling stress, carrying out daily routines, looking after one’s health, relaxing and leisure activities and doing house work. The impacts on quality of life and vocational performance were rather low. Conclusion The results show that long-term symptoms after mild and moderate COVID-19 are common and lead to limitations of activities and participation. However, it seems that in most cases they are not severe and do not lead to frequent or serious issues with quality of life or work ability.


2018 ◽  
Vol 14 (4) ◽  
pp. 776-791
Author(s):  
Veronika V. Nourkova ◽  
Alena A. Gofman ◽  
Mikhail D. Kozlov

While such factors as demand characteristics, encoding, and retrieval inhibition were shown to be significant in producing the directed forgetting effect, no attention was paid to whether the intention to manage one’s own memory, per se, matters. In the present article, we addressed this important gap in the literature. To control the quality of encoding we ensured that both the to-be-remembered (TBR) and to-be-forgotten (TBF) items were genuinely learned before the manipulation. We used extremely long delays between the memory instructions and testing to release inhibition associated with the content of instructions. 98 participants demonstrated flawless recall of 12 Russian - made up language word pairs. They then viewed each Russian word from a pair once, with randomized instructions “Forget”, “Remember”, “Repeat”, or a short cognitive task. Self-reports on the mnemonic strategies were collected. Free recall and recognition tests were administered three times - 45 minutes, a month and a year (N = 58) later. Despite a strong incentive to recall all word pairs, fewer TBF pairs were recalled in comparison with TBR pairs, both after 45 minutes and after one month’s delay. Recognition among all conditions was equally high. A year later free recall was close to zero. In contrast, the TBR and TBF pairs were recognized equally better than pairs presented in “Repeat” and “Task” conditions. Thus, our results show that the intention to manage one’s own memory enhances the accessibility of memories at a very long time delay, no matter what type of instruction is issued.


2016 ◽  
Vol 31 (1_suppl) ◽  
pp. 125-129 ◽  
Author(s):  
Roshan Bootun ◽  
Alun H Davies

Management of varicose vein disease has changed drastically over the past decades. Since its introduction in vein practice, surgery has gone through several stages of evolution until the method of ligation with stripping eventually became and remained the standard for a long time. It was found to be effective at treating the condition and, indications of its beneficial impact on patients’ quality of life soon also became evident. However, being associated with significant morbidity, surgery gradually fell out of favour, especially, once the newer endovenous techniques were launched around the turn of the century. These endothermal methods allowed procedures to be carried out under local anaesthetic as day case interventions, often with a similar or even better effect on occlusion rates and quality of life. In addition, there is mounting evidence that these newer techniques might be more cost-effective. This review evaluates surgical treatment of varicose veins compared to endovenous methods and also assesses its place in current phlebological practice.


2012 ◽  
Vol 151 ◽  
pp. 700-702
Author(s):  
Hua Zhang

As health is a major event in life, almost as a kind of urbanites’ Consensus, and spending money on health, taking the time to exercise has become a must of some people in life. In order to better guide the middle-aged women in scientific fitness training, this paper plans to analyze the following issues: the physical status of infrequent exercise of older women, fitness exercises on the impact of middle-aged women, the comparison about different types of fitness training methods on the impact of middle-aged women. The results shows long-term exercise can delay and change in body shape and quality of the middle-aged women on the law of aging, and can prevent the aging state such as being fat early, gaining weight, decreasing physical fitness. Physical exercise has enhanced the middle-aged women’s function of cardio-cerebral-vascular system and respiratory system. The exercisers who insist for a long time have obviously higher cardiopulmonary load ability than those who have no exercise.


2021 ◽  
Vol 13 (3) ◽  
pp. 93-98
Author(s):  
D. R. Khasanova ◽  
Yu. V. Zhitkova ◽  
G. R. Vaskaeva

In the context of the COVID-19 pandemic, healthcare is faced with several new problems, one of which is a post-covid syndrome. Symptoms in many COVID-19 survivors can persist for a long time, significantly affecting the quality of life and work performance. All of the above makes post-covid syndrome a socially significant disease, requires dynamic follow-up of such patients, and rehabilitation programs development. We are currently at the stage of accumulating knowledge about the SARS-CoV-2 pathophysiology and morphogenesis and its long-term consequences. This article discusses neuropsychiatric aspects of the post-covid syndrome: pathogenetic hypotheses, clinical features, and potentially promising treatment strategies.


Author(s):  
Judit Váradi

Cultural heritage is a socially created and interpreted narrative, which becomes interpretable through cultural transfer (Sagrillo, 2018). The role of culturally creative communities in shaping and maintaining cultural constructs has always been decisive. Lasting values are determined by cultural choice. Through crossing cultural and historical boundaries, music a deeply coded discourse establishes communication at all times. The experience and emotional effects produced by music are based on previous experiences, emotional reactions, and memories. The art of listening to music has always been governed by the social norms and etiquette of the period, which also dictate the nature and quality of reception. The history of listening to music has, however, enjoyed little academic attention. Since it is an unobservable and amorphous phenomenon, it was defined as a natural receptive process for a long time. Only in recent decades has the question come into focus as various disciplines have explored short-term and long-term transformative processes to reveal the effect of social, political, and economic characteristics of several eras. Keywords: listening to music, musical experience, receiving competence, concert


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