From behavioral risk factors to metabolic risk factors of non-communicable diseases: a path analysis using national survey data in Vietnam

Author(s):  
Thi Hoang Lan Vu ◽  
Quynh Long Khuong ◽  
Quynh Nga Pham ◽  
Tuan Lam Nguyen ◽  
Quoc Bao Tran ◽  
...  
Author(s):  
Nam Jeong Jeong ◽  
Eunil Park ◽  
Angel P. del Pobil

Non-communicable diseases (NCDs) are one of the major health threats in the world. Thus, identifying the factors that influence NCDs is crucial to monitor and manage diseases. This study investigates the effects of social-environmental and behavioral risk factors on NCDs as well as the effects of social-environmental factors on behavioral risk factors using an integrated research model. This study used a dataset from the 2017 Korea National Health and Nutrition Examination Survey. After filtering incomplete responses, 5462 valid responses remained. Items including one’s social-environmental factors (household income, education level, and region), behavioral factors (alcohol use, tobacco use, and physical activity), and NCDs histories were used for analyses. To develop a comprehensive index of each factor that allows comparison between different concepts, the researchers assigned scores to indicators of the factors and calculated a ratio of the scores. A series of path analyses were conducted to determine the extent of relationships among NCDs and risk factors. The results showed that social-environmental factors have notable effects on stroke, myocardial infarction, angina, diabetes, and gastric, liver, colon, lung, and thyroid cancers. The results indicate that the effects of social-environmental and behavioral risk factors on NCDs vary across the different types of diseases. The effects of social-environmental factors and behavioral risk factors significantly affected NCDs. However, the effect of social-environmental factors on behavioral risk factors was not supported. Furthermore, social-environmental factors and behavioral risk factors affect NCDs in a similar way. However, the effects of behavioral risk factors were smaller than those of social-environmental factors. The current research suggests taking a comprehensive view of risk factors to further understand the antecedents of NCDs in South Korea.


BMJ Open ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. e049565
Author(s):  
Tilahun Tewabe Alamnia ◽  
Wubshet Tesfaye ◽  
Solomon Abrha ◽  
Matthew Kelly

ObjectivesNon-communicable diseases (NCDs) are causing a new and yetsignificant health challenge in low-income countries. In Ethiopia, although 39% of deaths are NCD related, the health system remains underprepared, highlighting the clear need for evidence on risk factor distributions to inform resource planning and the health response. Therefore, this review investigates prevalence distributions and sex and age variations of metabolic risk factors among Ethiopian adults.Research design and methodsThis systematic review used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Studies published until 6 January 2021 were searched from PubMed, Scopus, ProQuest and Web of Science databases, reference lists of selected studies and grey literature. Studies reporting prevalence of metabolic risk factors: overweight/obesity, hypertension, impaired glucose homoeostasis and metabolic syndrome among Ethiopian adults were eligible for this systematic review and meta-analysis. Two authors independently extracted data and used the Joanna Briggs Institute tool for quality appraisal. The random effects model was used to conduct meta-analysis using Stata V.16. Subgroup analyses examined prevalence differences by region, study year, sample size and settings.ResultsFrom 6087 records, 74 studies including 104 382 participants were included. Most showed high prevalence of metabolic risk factors. Meta-analysis revealed pooled prevalence of metabolic risk factors from 12% to 24% with the highest prevalence observed for overweight/obesity (23.9%, 95% CI 19.9% to 28.0%) and hypertension (21.1%, 95% CI 18.7% to 23.5%), followed by metabolic syndrome (14.7%, 95% CI 9.8% to 19.6%) and impaired glucose tolerance (12.4%, 95% CI 8.7% to 16.1%). The prevalence of overweight/obesity was higher in women. All metabolic risk factors were higher among people aged above 45 years.ConclusionsA signficant proportion of Ethiopian adults have at least one metabolic risk factor for NCDs. Despite heterogeneity of studies limiting the certainty of evidence, the result suggests the need for coordinated effort among policymakers, healthcare providers, non-governmental stakeholders and the community to implement appropriate preventive measures to reduce these factors.


2020 ◽  
Author(s):  
Sphamandla Josias Nkambule ◽  
Indres Moodley ◽  
Desmond Kuupiel ◽  
Tivani P. Mashamba-Thomson

Abstract BackgroundIn previous studies, food insecurity has been hypothesised to promote the prevalence of metabolic risk factors on the causal pathway to diet-sensitive non-communicable diseases (NCDs). This prevalence has been shown to differ between gender and populations. However, evidence of this association in resources-limited settings with high levels of food insecurity such as sub-Saharan African countries remains elusive.PurposeWe aimed to identify the association between food insecurity and key metabolic risk factors on the causal pathway to diet-sensitive NCDs in sub-Saharan African population.MethodsWe did a systematic review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Relevant studies published between January 2015 and October 2019 were searched in PubMed, Web of Science (SCiELO Citation Index), and five other databases followed by explicit and reproducible hand-searches of included studies which were peer-reviewed epidemiological studies conducted in sub-Saharan Africa, directly measured food insecurity, and compared food insecurity to a metabolic risk factor outcome. Two reviewers extracted all the necessary data from individual studies independently and employed the Mixed Methods Appraisal Tool (MMAT) – Version 2018 to evaluate the risk of bias. Prevalence estimates from individual studies were pooled using the random-effect model.ResultsThe initial searches yielded 11 803 articles, 22 were eligible for inclusion, presenting data from 26 609 food-insecure participants and 11 545 incident of metabolic risk factor cases. Most studies confirmed an adverse association between food insecurity and key metabolic risk factors for diet-sensitive NCDs. The Meta-analysis showed a significantly high pooled prevalence estimate of key metabolic risk factors at 41.8 per cent (95% CI: 33.2% to 50.8%, I2 = 99.5% p-value < 0.00). The most prevalent type of metabolic risk factors was dyslipidaemia 27.6 per cent (95% CI: 6.5% to 54.9%), hypertension 24.7 per cent (95% CI: 15.6% to 35.1%), and overweight 15.8 per cent (95% CI: 10.6% to 21.7%). Notably, the prevalence estimates of these metabolic risk factors were considerably more frequent in females than males.ConclusionThis study is the first to systematically review or meta-analyse the association between food insecurity and key metabolic risk factors for diet-sensitive non-communicable diseases (NCDs) in sub-Saharan African countries, in order to generate an integrated, evidence-based, comprehensive summary of how key metabolic risk factors are patterned by food insecurity. Further high-quality longitudinal data and mediation analysis are warranted to understand the basis of this findings to support targeted prevention and control strategies for those confronted with food insecurity.PROSPERO registration number: PROSPERO 2019 CRD42019136638


2018 ◽  
Vol 4 (1) ◽  
pp. 60-66
Author(s):  
Soni Shrestha ◽  
Radha Kumari Paudel ◽  
Nisha Shrestha

Non Communicable Diseases are the biggest cause of death worldwide. There are eight major risk factors, out of which four of them are behavioral risk factors (tobacco use, harmful alcohol consumption, unhealthy diets and physical inactivity) and four of them are biological risk factors. The general objective of this study is to assess prevalence of behavioral risk factors of non-communicable diseases among adolescents. The study was conducted on students of higher secondary schools of Lalitpur. A descriptive cross-sectional study was conducted with the sample size 396. Structured questionnaire developed by STEPS SURVEY Nepal 2013 was used for data collection. Data management, analysis and interpretation were done using SPSS 20 version by calculating frequency and percentage. The prevalence of current tobacco (smoking) consumption was 17.2% and the prevalence of smokeless tobacco consumption was 8.1%. Current alcohol consumption was 14.4%. The prevalence of inadequate vigorous intensity activity was 58.3% and moderate intensity activity was 50.5%. The prevalence of fruit and vegetables consumption was 21.2% and 60.4% respectively. On the basis of findings of study it is concluded that use of tobacco products and alcohol was higher in male than female. All of the students consumed fruits and vegetables at least once a day but none of adolescents follow the consumption of fruits and vegetables as recommended by WHO. The adolescents were active as they involved in both vigorous and moderate intensity activity. The private schools students were less involved in physical activity as compared to public schools.


2013 ◽  
Vol 34 (3) ◽  
pp. 39-43
Author(s):  
K Adhikari ◽  
MR Adak

Introduction: Cardiovascular and other chronic diseases are becoming the major causes of morbidity and mortality in most of the third world countries, including Nepal. Unhealthy diet, physical inactivity and consumption of tobacco, alcohol, drugs etc. are major global determinants of non-communicable diseases and contribute to the excess death and disability among the poor in terms of mortality. This study was done to estimate the prevalence of behavioral risk factors of NCDs among adolescent. Methods: A cross sectional study based on WHO stepwise approach for surveillance of Non- Communicable Diseases (NCDs) risk factors was conducted in Chitwan District to assess the risk factors of NCDs. Information was collected on substance abuse, dietary habits and physical activity through personal interview. Results: A bout 50% male and 30% female respondents were currently abusing one or other forms of substance. Male (39%) and female (26%) were using tobacco products. It was found that only 14% of respondents were doing satisfactory level of physical activities. Conclusions: Substantially high levels of the various behavioral risk factors among adolescents in Chitwan District suggest an urgent need for awareness raising programmes. DOI: http://dx.doi.org/10.3126/joim.v34i3.8916 Journal of Institute of Medicine, December, 2012; 34:39-43  


2021 ◽  
Vol 11 (3) ◽  
pp. 217-224
Author(s):  
I. A. Krylova ◽  
V. I. Kupaev ◽  
A. V. Ljamin

The earliest correction of behavioral risk factors for chronic non-communicable diseases will reduce the rates of premature mortality of the population. Currently, the relationship between the altered spectrum of intestinal microflora in various indicators of suboptimal health status and body mass index is not sufficiently studied. When they are in a state of suboptimal health status, patients consider themselves healthy and do not go to the doctor for a long time, which makes it difficult to implement early preventive measures in this group of patients. Goal. To determine the qualitative and quantitative composition of the intestinal microflora before and 1 month after taking a metaprebiotic complex containing dietary fiber (inulin) and oligosaccharides (oligofructose) in outpatient patients who consider themselves healthy, have behavioral risk factors for chronic non-communicable diseases or chronic non-communicable diseases in remission, and/or do not consult a doctor within the last 3 months. Materials and methods. Outpatient patients were examined (114 people: 36 men, 78 women aged 18 to 72 years). A survey was conducted, including a detailed active collection of complaints (including using the international SHSQ-25 questionnaire) and anamnesis, as well as a thorough physical examination with an anthropometric study. Using the MALDI-ToF mass spectrometry method, the degree of microbiotic disorders, the structure of the intestinal microflora were determined with the identification of microorganisms isolated from feces before and after taking the course of the metaprebiotic complex with various indicators of suboptimal status and body mass index. Results. New data were obtained on the intestinal biocenosis of patients who consider themselves healthy at different levels of suboptimal status. When using a metaprebiotic complex containing inulin and oligofructose, an improvement in the composition of the intestinal microflora was found due to a decrease in the frequency of release of conditionally pathogenic enterobacteria and other gram-negative microorganisms (median degree of contamination: from 0.45 (0.3-0.98) to 0.3(0.21-0.7) at low suboptimal status and from 0.5(0.7-1.7) to 0.31 (0.2-1.3) at high) and increase the frequency of enterococcal excretion (median degree of contamination: from 5,58 (4,16-7,0) tо 6,3 (4,8-7,8) at low suboptimal status and from от 4,5 (2,8-6,3) tо 5,1 (3,8-6,4) at high). Conclusion. The importance of studying the microbiotic complex of the intestine in increasing the indicators of suboptimal health status and body mass index in patients who consider themselves healthy is proved, which will allow for the earliest detection and rational individual prevention of chronic non-communicable diseases.


Sign in / Sign up

Export Citation Format

Share Document