Calcium phosphate (CaP) biomaterials containing Chinese medicine, Danshen (Salvia
Miltiorrhiza Bunge, SMB), have been synthesized in our previous study via the wet chemical
method. However, CaP biomaterials were generally synthesized in the alkaline solution. The
purpose of the present study was to investigate the effect of pH on SMB and the influence of SMB
on the synthesis of CaP biomaterials. The SMB solutions of different pH from 5.0 to 10.0, were
scanned with the UV-VIS spectrophotometer (UV-VIS) in the wavelength ranged from 200.00 to
400.00 nm. CaP biomaterials containing SMB were synthesized from (NH4)2HPO4, Ca(NO3)2,
NH4OH and SMB. The filtrates of the wet synthesis of CaP biomaterials containing SMB were
measured by UV-VIS. The synthesized CaP biomaterials containing SMB were characterized by the
X-ray diffraction (XRD) and Fourier-transform infrared spectroscopy (FTIR). The results showed
that the maximum absorption peak appeared at 281.00 nm for solutions of pH 5.0, 6.0 and 7.0.
Although there were a new absorption peaks as the pH were 8.0 and 9.0, the absorption curves of
SMB became similar to that of SMB as pH at 7.0 after the pH were readjusted to 7.0. The
absorption peak appeared an Einstein shift to 347.00 nm at pH 10.0, which did not return to 281.00
nm when the pH of SMB solution was readjusted to 7.0. The absorption peak of filtrates containing
SMB of CaP biomaterials reaction system was still at 281.00 nm when their pH was 7.0 and 8.0.
Moreover, SMB had no obvious effect on the phase component and functional groups of products.
Hence, it could be predicted that calcium phosphate biomaterials containing SMB, such as DCPD
and TCP containing SMB, which could be prepared at the pH ranged from 5.0 to 9.0.
Microwave-Assisted Fabrication of Mesoporous Silica-Calcium Phosphate Composites for Dental Application