scholarly journals Evaluating Mechanisms: Mapping Weekly Dynamics between Experiential Avoidance and SAD Symptoms

Author(s):  
Laurel D. Sarfan ◽  
Joshua C. Magee ◽  
Elise M. Clerkin

AbstractWidely-used, empirically-supported treatments focus on reducing experiential avoidance (EA) as a mechanism of social anxiety disorder (SAD) symptom change. However, little is known about how EA and SAD symptoms bidirectionally interrelate from session to session, or throughout the course of an intervention—a gap that raises significant theoretical and clinical questions about the mechanistic role of EA. Participants (N = 78) with elevated EA and SAD symptoms completed a 3-session pilot intervention (Approach-Avoidance Task training plus psychoeducation) designed to target EA. Bivariate latent change score modeling was then used to map the bidirectional, temporal interrelationships between EA and SAD symptoms from session to session. Analyses accounted for the overall trajectory of change in both variables (i.e., EA and SAD) and both variables’ preceding measurement. Findings suggested that changes in SAD symptoms preceded and predicted changes in EA from session to session. Contrary to hypotheses, this effect was not bidirectional, as changes in EA did not precede and predict changes in SAD symptoms from session to session. The use of a relatively small analogue sample limit the external validity of the present findings. Nevertheless, these novel findings advance our understanding of the dynamic interrelationships between EA and SAD symptoms throughout treatment. Moreover, given that many leading treatments target EA, this study highlights a need for future work to continue evaluating whether EA is indeed a mechanism of SAD symptom change.

2007 ◽  
Author(s):  
Rebecca M. Pasillas ◽  
Mark Stalnaker ◽  
Jason Deviva ◽  
Andrew Santanello ◽  
Melissa Decker ◽  
...  

Author(s):  
Shardé M. Davis

Investigating the role of physiology in communication research is a burgeoning area of study that has gained considerable attention by relational scholars in the past decade. Unfortunately, very few published studies on this topic have evoked important questions about the role of race and ethnicity. Exploring issues of ethnicity and race provides a more holistic and inclusive view of interpersonal communication across diverse groups and communities. This chapter addresses the gap in literature by considering the ways in which race and ethnicity matter in work on physiology and interpersonal interactions. More specifically, this chapter will first discuss the conceptual underpinnings of race, ethnicity, and other relevant concepts and then review extant research within and beyond the field of communication on race, ethnicity, interpersonal interactions, and physiology. These discussions set the foundation for this chapter to propose new lines of research that pointedly connect these four concepts and advance key principles that scholars should consider in future work.


2021 ◽  
Vol 22 (4) ◽  
pp. 1991
Author(s):  
Jimok Yoon ◽  
Heng Wu ◽  
Ruei-Jiun Hung ◽  
Jonathan R. Terman

To change their behaviors, cells require actin proteins to assemble together into long polymers/filaments—and so a critical goal is to understand the factors that control this actin filament (F-actin) assembly and stability. We have identified a family of unusual actin regulators, the MICALs, which are flavoprotein monooxygenase/hydroxylase enzymes that associate with flavin adenine dinucleotide (FAD) and use the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH) in Redox reactions. F-actin is a specific substrate for these MICAL Redox enzymes, which oxidize specific amino acids within actin to destabilize actin filaments. Furthermore, this MICAL-catalyzed reaction is reversed by another family of Redox enzymes (SelR/MsrB enzymes)—thereby revealing a reversible Redox signaling process and biochemical mechanism regulating actin dynamics. Interestingly, in addition to the MICALs’ Redox enzymatic portion through which MICALs covalently modify and affect actin, MICALs have multiple other domains. Less is known about the roles of these other MICAL domains. Here we provide approaches for obtaining high levels of recombinant protein for the Redox only portion of Mical and demonstrate its catalytic and F-actin disassembly activity. These results provide a ground state for future work aimed at defining the role of the other domains of Mical — including characterizing their effects on Mical’s Redox enzymatic and F-actin disassembly activity.


Perfusion ◽  
2021 ◽  
pp. 026765912098653
Author(s):  
Hafiz Naderi ◽  
Shaun Robinson ◽  
Martin J Swaans ◽  
Nina Bual ◽  
Wing-See Cheung ◽  
...  

The COVID-19 pandemic has altered our approach to inpatient echocardiography delivery. There is now a greater focus to address key clinical questions likely to make an immediate impact in management, particularly during the period of widespread infection. Handheld echocardiography (HHE) can be used as a first-line assessment tool, limiting scanning time and exposure to high viral load. This article describes a potential role for HHE during a pandemic. We propose a protocol with a reporting template for a focused core dataset necessary in delivering an acute echocardiography service in the setting of a highly contagious disease, minimising risk to the operator. We cover the scenarios typically encountered in the acute cardiology setting and how an expert trained echocardiography team can identify such pathologies using a limited imaging format and include cardiac presentations encountered in those patients acutely unwell with COVID-19.


2017 ◽  
Vol 36 (4) ◽  
pp. 309-325 ◽  
Author(s):  
Wangzhong Mu ◽  
Pär Göran Jönsson ◽  
Keiji Nakajima

AbstractIntragranular ferrite (IGF), which nucleates from specific inclusion surfaces in low alloy steels, is the desired microstructure to improve mechanical properties of steel such as the toughness. This microstructure is especially important in the coarse grain heat affected zone (CGHAZ) of weldments. The latest review paper focusing on the role of non-metallic inclusions in the IGF formation in steels has been reported by Sarma et al. in 2009 (ISIJ int., 49(2009), 1063–1074). In recent years, large amount of papers have been presented to investigate different issues of this topic. This paper mainly highlights the frontiers of experimental and theoretical investigations on the effects of inclusion characteristics, such as the composition, size distribution and number density, on the IGF formation in low carbon low-alloyed steels, undertaken by the group of Applied Process Metallurgy, KTH Royal Institute of Technology. Related results reported in previous studies are also introduced. Also, plausible future work regarding various items of IGF formation is mentioned in each section. This work aims to give a better control of improving the steel quality during casting and in the heat affected zone (HAZ) of weldment, according to the concept of oxide metallurgy.


2012 ◽  
Vol 29 (3) ◽  
pp. 371-385 ◽  
Author(s):  
Serkan Perkmen ◽  
Beste Cevik ◽  
Mahir Alkan

Guided by three theoretical frameworks in vocational psychology, (i) theory of work adjustment, (ii) two factor theory, and (iii) value discrepancy theory, the purpose of this study was to investigate Turkish pre-service music teachers' values and the role of fit between person and environment in understanding vocational satisfaction. Participants were 85 students enrolled in the department of music education in a Turkish university. The Minnesota Importance Questionnaire (MIQ) was used to examine the participants’ values in six dimensions: achievement, comfort, status, altruism, safety and autonomy. Results revealed that the pre-service teachers value achievement most followed by autonomy, which suggests that they would like to have a sense of accomplishment and control in their future job. The degree to which their values fit their predictions about future work environment was found to be highly correlated with vocational satisfaction. These results provided evidence that the vocational theories used in the current study offers a helpful and different perspective to understand the pre-service teachers' satisfaction with becoming a music teacher in the future. We believe that researchers in the field of music education may use these theories and MIQ to examine the role of values in pre-service and in-service music teachers' job satisfaction.


2021 ◽  
pp. 1-29
Author(s):  
Minh-Cam Duong ◽  
Hung Nguyen-Viet ◽  
Delia Grace ◽  
Chhay Ty ◽  
Huy Sokchea ◽  
...  

Abstract Objective: To examine whether mothers’ perceived neighborhood food access is associated with their own and their young children’s consumption of animal-flesh food, fruits and vegetables in peri-urban areas of Cambodia. Design: A cross-sectional survey measured food consumption frequency and perceived neighborhood food access, the latter including six dimensions of food availability, affordability, convenience, quality, safety and desirability. Multivariate logistic regression was used to assess the association between food access and food consumption. Setting: Peri-urban districts of Phnom Penh and Siem Reap, Cambodia Participants: 198 mothers of children between 6 to 24 months old. Results: Over 25% of the mothers and 40% of the children had low consumption (< once a day) of either animal-flesh food or fruits and vegetables. Compared with perceived high food access, perceived low food access was associated with an adjusted 5.6-fold and 4.3-fold greater odds of low animal-flesh food consumption among mothers (95% CI 2.54, 12.46) and children (95% CI 2.20, 8.60) respectively. Similarly, relative to perceived high access, perceived low food access was associated with 7.6-times and 5.1-times higher adjusted odds of low fruits and vegetables consumption among mothers (95% CI 3.22, 18.02) and children (95% CI 2.69, 9.83) respectively. Conclusions: Mothers’ perceived neighborhood food access was an important predictor of their own and their young children’s nutrient-rich food consumption in peri-urban Cambodia. Future work is needed to confirm our findings in other urban settings and examine the role of neighborhood food environment on the consumption of both nutrient-rich and nutrient-poor food.


2021 ◽  
Author(s):  
Rohan Prabhu ◽  
Mohammed Alsager Alzayed ◽  
Elizabeth Starkey

Abstract Empathy plays an important role in designers’ ability to relate to problems faced by others. Several researchers have studied empathy development in engineering design education; however, a majority of this work has focused on teaching designers to empathize with primary users. Little attention in empathy development research is given to empathizing with those affected in a secondary and tertiary capacity. Moreover, little research has investigated the role of students’ empathy in influencing their emphasis on sustainability, especially in the concept evaluation stage. Our aim in this paper is to explore this research gap through an experimental study with engineering students. Specifically, we introduced first-year engineering students at a large public university in the northeastern United States to a short workshop on sustainable design. We compared changes in their trait empathy and attitudes towards sustainability from before to after participating in the workshop. We also compared the relationship between students’ trait empathy, attitudes towards sustainability, and the self-perceived sustainability of their solutions in a design task. From our results, we see that students reported an increase in their beliefs and intentions towards sustainability and a decrease in their personal distress from before to after participating in the workshop. Furthermore, students’ trait empathy correlated negatively with the self-perceived sustainability of their solutions. These findings highlight the need for future work studying the role of empathy in encouraging a sustainable design mindset among designers.


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