scholarly journals Application of Poly (Agar-Co-Glycerol-Co-Sweet Almond Oil) Based Organo-Hydrogels as a Drug Delivery Material

2021 ◽  
Author(s):  
Tuba Ersen Dudu ◽  
Duygu Alpaslan ◽  
Nahit Aktas
Keyword(s):  
Drug Delivery ◽  
Almond Oil ◽  
Sweet Almond

scholarly journals Effect of Body Lotions on Capillary Blood Glucose Measurement – Interference of Hydroquinone-containing Body Lotion with Capillary Glucose Measurement

2018 ◽  
Vol 14 (1) ◽  
pp. 44
Author(s):  
Andrea MA Omengue ◽  
Eugène Sobngwi ◽  
Mesmin Dehayem ◽  
Eric V Balt ◽  
Anne MO Boli ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Glucose Level ◽  
Capillary Blood ◽  
Glucose Measurement ◽  
Capillary Blood Glucose ◽  
Almond Oil ◽  
Patients With Diabetes ◽  
Capillary Glucose ◽  
The Impact ◽  
Sweet Almond

The reliability of capillary blood glucose measurements is tremendously important for patients’ care and follow-up. Some factors independent of glucose control could however affect readings during ambulatory monitoring of capillary glucose levels in patients with diabetes mellitus. We sought to evaluate the impact of three body lotions commonly used in Cameroon on different strata of glycaemia. We explored their influence over time on measured capillary glucose values. We enrolled 16 participants. Eligible individuals were adult patients with diabetes (n=12) stratified into three levels of capillary glucose values (100 ± 40 mg/dL [5.55 ± 2.22 mmol/L], 200 ± 40 mg/dL [11.1 ± 2.22 mmol/L] and 300 ± 40 mg/dL [16.65 ± 2.22 mmol/L]) and normoglycaemic individuals (n=4). We measured capillary blood glucose before application, immediately after, then 5, 30 and 60 minutes after application of sweet almond oil, corticosteroid cream and hydroquinone lotion. The measurements made on impregnated body lotion-permeated fingers were compared to that of a clean finger. We observed a significant increase (delta [95% confidence interval, CI]: 119.5% [77.4–222.1]) of capillary glucose level immediately after administration of hydroquinone-containing body lotion (p<0.001). Capillary glucose values after the use of corticoid cream and sweet almond oil was stable 5, 30 and 60 minutes after application (p=0.875 and p=0.883 respectively). In the case of the hydroquinone-containing body lotion, there was a significant difference between capillary glucose level at 5 minutes (delta [95%CI]: 81.6% [55.3–214.2]; p<0.001), 30 minutes (delta [95%CI]: 71.6% [21.8–134.6]; p<0.001) and 60 minutes (delta [95%CI]: 58.3% [2.8–133.3]; p=0.013) after application compared to the value obtained from the clean finger. We observed from our study that there were significant variations in capillary blood glucose measurements induced by the use of hydroquinone lotion.

The effect of Aloe vera gel and sweet almond oil on striae gravidarum in nulliparous women

2017 ◽  
Vol 31 (13) ◽  
pp. 1703-1708 ◽  
Author(s):  
Maryam Hajhashemi ◽  
Mahmoud Rafieian ◽  
Hojjat Allah Rouhi Boroujeni ◽  
Sepideh Miraj ◽  
Shadman Memarian ◽  
...  
Keyword(s):  
Aloe Vera ◽  
Almond Oil ◽  
Nulliparous Women ◽  
Aloe Vera Gel ◽  
Striae Gravidarum ◽  
Sweet Almond

scholarly journals Physical properties and caffeine release from creams prepared with different oils

2014 ◽  
Vol 27 (4) ◽  
pp. 224-228 ◽  
Author(s):  
Katarzyna Wojciechowska ◽  
Maria Zun ◽  
Dorota Dwornicka ◽  
Katarzyna Swiader ◽  
Regina Kasperek ◽  
...  
Keyword(s):  
Mode Of Delivery ◽  
Coconut Oil ◽  
Sesame Oil ◽  
Jojoba Oil ◽  
Walnut Oil ◽  
Almond Oil ◽  
Coffee Arabica ◽  
The Central Nervous System ◽  
Physical Tests ◽  
Sweet Almond

Abstract Caffeine is a methylxanthine typically found in the Coffee Arabica L plant. Generally, caffeine is well-known as a orally administered mild stimulant of the central nervous system. However, for cosmetic purpose, caffeine is an active compound ingredient, at 7% concentration, in several anticellulite products. The efficiency of this mode of delivery is not fully understood. Hence, the aim of the study was to ascertain the effectiveness of particular carriers to release this ingredient. In so doing, we prepared six creams based upon different oils (Sesame oil, Rice oil, Walnut oil, Coconut oil, Sweet almond oil and Jojoba oil), containing 5% of caffeine, and compared the release of the substance from the obtained preparations. Initially, all of the creams were subjected to a variety of physical tests, among these being for slippage and spreadability. Furthermore, their rheological properties were evaluated. Subsequently, the creams were tested for caffeine release. In the slippage and spreadability tests, the coconut oil-based cream was revealed as having the best parameters. However, the rheological tests showed that all of the preparations had the pseudoplastic character of flowing according to the Ostwald de Waele power law model. The power low index (n) for all the preparations was from 0.2467-0.3179 at 20°C and 0.2821-0.3754 at 32°C. At 20°C, the Sesame oil-, Walnut oil-, Sweet almond oil- and Jojoba oil-based creams were thixotropic, but at 32°C, thixotropy appeared only in the Walnut oil-based creams. The release studies, conducted by way of an extracting chamber (according to Polish Pharmacoeia IX) in the Paddle Apparatus (according to Polish Pharamcopoeia IX), showed that the amount of released caffeine is the largest in the case of Jojoba oil-based cream, at 85.23% ± 0.8% (SD), and the least in the case of Coconut oil-based cream, at 62,78%± 0.87% (SD).

Application of Newly Synthesized Sulfobetaine Based on Sweet Almond Oil in Bath Liquids for Sensitive Skin

2021 ◽  
Vol 58 (2) ◽  
pp. 106-113
Author(s):  
Emilia Klimaszewska ◽  
Daria Wieczorek ◽  
Artur Seweryn ◽  
Marta Ogorzałek
Keyword(s):  
Molecular Structures ◽  
Sulfonate Group ◽  
Albumin Solution ◽  
Sensitive Skin ◽  
Almond Oil ◽  
Quaternary Nitrogen ◽  
Ph Increase ◽  
Cocamidopropyl Betaine ◽  
Positively Charged ◽  
Sweet Almond

Abstract Three formulations for bath liquids were developed, differing in the type of amphoteric surfactant applied. The formulations used Cocamidopropyl Betaine, Cocamidpropyl Hydroxide and newly synthesized sulfobetaine based on sweet almond oil (Oleicamidopropyl Sultaine). The molecular structure of the surfactant used in the manufactured formulations has a negatively charged sulfonate group and a positively charged quaternary nitrogen atom. Such molecular structures suggest that the functional properties of this substance are mild. Based on the research, it was found that the bath fluid containing the newly synthesized sulfobetaine based on sweet almond oil had the lowest zein number, the lowest pH increase of bovine albumin solution and the lowest ability to emulsify fatty dirt. This indicates a very low irritant effect of the tested bath liquid.

Effect of sweet almond oil on survival rate and plasma cholinesterase activity of aluminum phosphide-intoxicated rats

2011 ◽  
Vol 31 (5) ◽  
pp. 518-522 ◽  
Author(s):  
Hossein Saidi ◽  
Shayan Shojaie
Keyword(s):  
Survival Rate ◽  
Cholinesterase Activity ◽  
Plasma Cholinesterase ◽  
Control Group ◽  
Aluminum Phosphide ◽  
Time Intervals ◽  
Almond Oil ◽  
Plasma Cholinesterase Activity ◽  
Reduction Of Mortality ◽  
Sweet Almond

Introduction: Aluminum phosphide (ALP), as an effective pesticide and a substance used for protecting rice during storage, has become one of the commonest causes of poisoning and even suicide in developing countries including Iran and India. The authors aimed to study the efficacy of sweet almond oil as an antidote in ALP toxicity. Methods: The present experimental study was conducted over 35 rats. The animals were divided into four groups: one group as the control group and three other groups which received ALP alone or ALP and sweet almond oil with different time intervals. In addition to estimating the survival rate of the animals, plasma cholinesterase activity as a possible factor affected in ALP poisoning was evaluated. Results: Treatment by intragastric irrigation of sweet almond oil resulted in significant reduction of mortality. Moreover, mean plasma cholinesterase levels were inhibited in groups receiving ALP. Conclusion: Oral sweet almond oil, if especially used immediately after poisoning with ALP, improves the survival rate.

scholarly journals Comparing the Effect of Foot Massage with Grape Seed Oil and Sweet Almond Oil on Physiological Leg Edema in Primigravidae: A Randomized Clinical Trial

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Maryam Navaee ◽  
Marzieh Rakhshkhorshid
Keyword(s):  
Clinical Trial ◽  
Pregnant Women ◽  
Randomized Clinical Trial ◽  
Seed Oil ◽  
Grape Seed ◽  
Control Group ◽  
Almond Oil ◽  
Grape Seed Oil ◽  
Leg Edema ◽  
Sweet Almond

Background. Leg edema is a prevalent problem in pregnancy causing activity restrictions for pregnant women. This study was performed to compare the effect of foot massage using grape seed oil and sweet almond oil on physiological leg edema. Methods. A randomized clinical trial was conducted on 90 primigravidae referred to public health centres of Zahedan, Iran. The participants’ gestational age was 30–40 weeks. The study was conducted from August 2016 to November 2017. The participants were randomly assigned to three groups (massage with grape seed oil, massage with sweet almond oil, and without intervention). After determining the extent of leg edema, foot massages were done for 20 minutes within 5 days in the two intervention groups. Then, foot circumferences were measured on day 5 after the intervention. Foot circumferences for the control group were measured on days 1 and 5. A nonelastic tape measure was used to measure the circumferences. To analyse the data, SPSS 21 software and statistical tests including one-way ANOVA, Tukey’s test, and paired t-test were used. Results. The results from this study showed a significant difference in the mean score change of foot circumferences between groups (P=0.001). According to the results of Tukey’s test, mean score changes of foot circumferences of both intervention groups were significantly different those of the control group. However, this difference was not significant between the two intervention groups (P=0.865). Conclusion. The findings of this study confirmed the effectiveness of foot massage using grape seed and sweet almond oils to reduce pregnancy physiological edema. Therefore, foot massage with appropriate oils can be used as a useful technique by trained midwives in prenatal care centres or at pregnant women houses. This trial is registered with IRCT2015072723370N1.

scholarly journals Application of poly (Agar-co-Glycerol-co-Sweet Almond Oil) based organohydrogels as a Drug Delivery Material

2021 ◽  
Author(s):  
Tuba Ersen Dudu ◽  
Duygu Alpaslan ◽  
Nahit Aktas
Keyword(s):  
Blood Compatibility ◽  
Release Kinetics ◽  
Antioxidant Properties ◽  
In Vitro Release ◽  
Skin Surface ◽  
Gastric Fluid ◽  
Polymerization Reaction ◽  
Almond Oil ◽  
Sweet Almond

Abstract In this study, it was aimed to investigate the synthesis, characterization and drug release behaviors of organohydrogels containing pH-sensitive Agar (A), Glycerol (G), Sweet Almond oil (SAO). Organohydrogels, which contained Agar, Glycerol and different amounts of Sweet Almond oil, were synthesized via the free-radical polymerization reaction with emulsion technique using glutaraldehyde or methylene bis acrylamide crosslinkers. Then, the degree of swelling, bond structures, blood compatibility and antioxidant properties of the synthesized organohydrogels were examined. In addition, Organohydrogels which loaded with Ceftriaxone (antibiotic) and Oxaliplatin (an anti-cancer agent), were synthesized with the same polymerization reaction and release kinetics were investigated. In vitro release studies were performed at media similar pH to gastric fluid (pH 2), skin surface (pH 5.5), blood fluid (pH 7.4) and intestinal fluid (pH 8), at 37° C. The effects on release of crosslinker type and sweet almond oil amount were investigated. Kinetic parameters were determined using release results and these results were applied to zero and first-order equations and Korsmeyer-Peppas and Higuchi equations. Diffusion exponential was calculated for drug diffusion of organohydrogels and values consistent with release results were found.

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