An efficient protocol for the synthesis of highly sensitive indole imines utilizing green chemistry: optimization of reaction conditions

2018 ◽  
Vol 22 (3) ◽  
pp. 709-722
Author(s):  
Bushra Nisar ◽  
Syeda Laila Rubab ◽  
Abdul Rauf Raza ◽  
Sobia Tariq ◽  
Ayesha Sultan ◽  
...  
Keyword(s):  
Green Chemistry ◽  
Reaction Conditions ◽  
Highly Sensitive

scholarly journals Correction to: An efficient protocol for the synthesis of highly sensitive indole imines utilizing green chemistry: optimization of reaction conditions

2018 ◽  
Vol 23 (1) ◽  
pp. 261-261
Author(s):  
Bushra Nisar ◽  
Syeda Laila Rubab ◽  
Abdul Rauf Raza ◽  
Sobia Tariq ◽  
Sana Jamshaid ◽  
...  
Keyword(s):  
Green Chemistry ◽  
Reaction Conditions ◽  
Highly Sensitive

scholarly journals FLUORESCENCE HISTOCHEMICAL DEMONSTRATION OF PEPTIDES WITH NH2- OR COOH-TERMINAL TRYPTOPHAN OR DOPA BY CONDENSATION WITH GLYOXYLIC ACID

1973 ◽  
Vol 21 (3) ◽  
pp. 253-265 ◽  
Author(s):  
ANDERS BJÖRKLUND ◽  
ROLF HAKANSON ◽  
OLLE LINDVALL ◽  
FRANK SUNDLER
Keyword(s):  
Acid Treatment ◽  
Spectral Characteristics ◽  
Glyoxylic Acid ◽  
Histochemical Demonstration ◽  
Reaction Conditions ◽  
Terminal Position ◽  
Acid Vapor ◽  
Cell Systems ◽  
Highly Sensitive ◽  
Sensitive Method

Condensation with glyoxylic acid vapor, recently introduced as a highly sensitive method for fluorescence histochemical visualization of biogenic monamines, has been found to allow also the demonstration of certain tryptophan- or dopa-containing peptides. Thus, in model experiments, treatment with glyoxylic acid vapor induced fluorescence from di- and tetrapeptides with tryptophan or dopa in NH2-terminal or COOH-terminal position. Peptides without tryptophan or dopa in terminal positions gave no observable fluorescence. Differences were recorded between peptides with NH2-terminal and COOH-terminal tryptophan with respect to their fluorescence yields under different reaction conditions and the spectral characteristics of the fluorophores (excitation/emission maxima: 375-380/500-520 nm and 340-370/435 nm, respectively). In addition, the tryptophan-containing peptides could be distinguished microspectrofluorometrically from the dopa-containing peptides. Thus, the fluorophore of the NH2-terminal dopa peptide had excitation/emission maxima at 330 and 380/495 nm, and the corresponding values for the fluorophore of the COOH-terminal dopa peptide were 330 and 370/460 nm. The glyoxylic acid treatment produced intense fluorescence in certain endocrine cell systems in pituitary, thyroid and gastric mucosa, previously suggested to store peptides with NH2-terminal tryptophan. The present findings support this hypothesis.

Ultrasound-Promoted Organic Synthesis – A Recent Update

2021 ◽  
Vol 25 ◽  
Author(s):  
Goutam Brahmachari ◽  
Nayana Nayek ◽  
Mullicka Mandal ◽  
Anindita Bhowmick ◽  
Indrajit Karmakar
Keyword(s):  
Organic Chemistry ◽  
Green Chemistry ◽  
Organic Synthesis ◽  
Ultrasound Irradiation ◽  
Present Review ◽  
Organic Transformations ◽  
Reaction Conditions ◽  
Catalytic Systems ◽  
Bond Forming ◽  
Reducing Energy

: Ultrasonication, nowadays, is well-regarded as an effective green tool in implementing a plethora of organic transformations. The last decade has seen quite useful applications of ultrasound irradiation in synthetic organic chemistry. Ultrasound has already come out as a unique technique in green chemistry practice, for its inherent properties of minimizing wastes and reducing energy and time, thereby increasing the product yields with higher purities under milder reaction conditions. The present review summarizes ultrasound-promoted useful organic transformations involving both carbon-carbon and carbon-heteroatom (N, O, S) bond-forming reactions in the absence or presence of varying catalytic systems, reported during the period 2016-2020.

A clean, simple and efficient synthesis of trans-[3-(aryl)-2,3-dihydrofuro[3,2-h] quinolin-2-yl]-(4-chlorophenyl)methanones

2017 ◽  
Vol 41 (7) ◽  
pp. 380-383
Author(s):  
Maryam Salari ◽  
Alireza Hassanabadi ◽  
Mohammad H. Mosslemin
Keyword(s):  
Reaction Time ◽  
Green Chemistry ◽  
Aromatic Aldehyde ◽  
Efficient Method ◽  
Efficient Synthesis ◽  
Reaction Conditions ◽  
Short Reaction Time ◽  
High Yields

We report a green and efficient method for the synthesis of trans-[3-(aryl)-2,3-dihydrofuro[3,2- h]quinolin-2-yl]-(4-chlorophenyl) methanones from the condensation of 2-[2-(4-chlorophenyl)-2-oxoethyl)]isoquinolinium bromide with 8-hydroxyquinoline and an aromatic aldehyde in the presence of catalytic amounts of choline hydroxide in water at reflux conditions. This new protocol employing choline hydroxide, which is a green and inexpensive catalyst, offers advantages such as mild reaction conditions, short reaction time, high yields and does not involve any hazardous solvent. Therefore, this procedure can be classified as green chemistry.

3-Amino-2-methylquinazolin-4-(3H)-one Schiff Bases Synthesis – a Green Chemistry Approach – a Comparison of Microwave and Ultrasound Promoted Synthesis with Mechanosynthesis.

2020 ◽  
Vol 07 ◽  
Author(s):  
Mario Komar ◽  
Fran Prašnikar ◽  
Tatjana Gazivoda Kraljević ◽  
Krunoslav Aladić ◽  
Maja Molnar
Keyword(s):  
Mass Spectrometry ◽  
Green Chemistry ◽  
Schiff Bases ◽  
13C Nmr Spectroscopy ◽  
Synthetic Methods ◽  
Reaction Conditions ◽  
1H And 13C Nmr ◽  
Microwave Assisted ◽  
Ultrasound Assisted ◽  
High Yields

: A green chemistry methods are important modern pathways in synthetic chemistry with main advantages such as milder reaction conditions, shorter time and higher yields. A series of quinazolinone based Schiff bases (1−27) have been successfully synthesized by using green synthetic methods including microwave-assisted, ultrasound-assisted and mechanochemical synthesis, respectively. Desired compounds were prepared from 3-amino-2-methylquinazolin-4(3H)- one and substituted benzaldehydes with moderate to high yields (11−90%). Benzoxazinone and 3-amino-2- methylquinazolin-4(3H)-one, the precursors of Schiff bases, were prepared by microwave induced synthesis. The structures of all Schiff bases are confirmed by 1H and 13C NMR spectroscopy and mass spectrometry as well. A novelty of this research is the application and comparison of green chemistry methods in the synthesis of desired compounds are listed above. The simplicity of synthesis includes ethanol as solvent and no need for further purification.

scholarly journals Simple Sensitive Spectrophotometric Determination of Vanadium in Biological and Environmental Samples

2006 ◽  
Vol 3 (4) ◽  
pp. 286-297 ◽  
Author(s):  
B. Krishna Priya ◽  
P. Subrahmanyam ◽  
J. Dilip Kumar ◽  
P. Chiranjeevi
Keyword(s):  
Biological Samples ◽  
Wave Length ◽  
Coupling Reaction ◽  
Basic Medium ◽  
Reaction Conditions ◽  
Highly Sensitive ◽  
Biological And Environmental Samples ◽  
Environmental And Biological Samples ◽  
Optimum Reaction

Novel, rapid, highly sensitive and selective spectrophotometric method for the determination of traces of vanadium (V) in environmental and biological samples, pharmaceutical and steel samples was studied. The method is based on oxidation of 2,4- dinitro phenyl hydrazine(2,4-DNPH) by vanadium (V) followed by coupling reaction withN-(1-naphthalene-1-yl)ethane-1,2-diamine-dihydrochloride (NEDA) in acidic medium to give red colored derivative or on oxidation of 4-Amino Pyridine by vanadium (V) followed by coupling reaction with NEDA in basic medium to give pink colored derivative. The red colored derivative having an λmax495 nm which is stable for 8 days and the pink colored derivative with 525 nm is stable for more than 7 days at 350C. Beer's law is obeyed for vanadium (V) in the concentration range of 0.02 - 3.5 μg mL–1(red derivative) and 0.03 – 4.5 μg mL–1(pink derivative) at the wave length of maximum absorption. The optimum reaction conditions and other analytical parameters were investigated to enhance the sensitivity of the present method. The detailed study of various interferences made the method more selective. The proposed method was successfully applied to the analysis of vanadium in natural water samples, plant material, soil samples, synthetic mixtures, pharmaceutical samples and biological samples. The results obtained were agreed with the reported methods at the 95 % confidence level. The performance of proposed method was evaluated in terms of Student'st-test and Variance ratiof-test which indicates the significance of proposed method over reported method.

scholarly journals Palladium Nanoparticles Fabricated by Green Chemistry: Promising Chemotherapeutic, Antioxidant and Antimicrobial Agents

Materials ◽  
2020 ◽  
Vol 13 (17) ◽  
pp. 3661 ◽  
Author(s):  
Sherif Fahmy ◽  
Eduard Preis ◽  
Udo Bakowsky ◽  
Hassan Mohamed Azzazy
Keyword(s):  
Green Chemistry ◽  
Physicochemical Properties ◽  
Plant Extracts ◽  
Palladium Nanoparticles ◽  
Biomedical Applications ◽  
Antimicrobial Agents ◽  
Reaction Conditions ◽  
Chemical Methods ◽  
Physical And Chemical

Palladium nanoparticles (Pd NPs) showed great potential in biomedical applications because of their unique physicochemical properties. Various conventional physical and chemical methods have been used for the synthesis of Pd NPs. However, these methods include the use of hazardous reagents and reaction conditions, which may be toxic to health and to the environment. Thus, eco-friendly, rapid, and economic approaches for the synthesis of Pd NPs have been developed. Bacteria, fungi, yeast, seaweeds, plants, and plant extracts were used to prepare Pd NPs. This review highlights the most recent studies for the biosynthesis of Pd NPs, factors controlling their synthesis, and their potential biomedical applications.

scholarly journals Hydrogenation of Some Vegetable Oils by Scrap Automobile Catalyst

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Fatih Sonmez ◽  
Hakan Ercan ◽  
Hayriye Genc ◽  
Mustafa Arslan ◽  
Mustafa Zengin ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Reaction Time ◽  
Green Chemistry ◽  
Vegetable Oils ◽  
Elaidic Acid ◽  
Sunflower Oil ◽  
Reaction Conditions ◽  
Catalyst Amount ◽  
Optimum Reaction ◽  
High Yields

Some vegetable oils were hydrogenated with scrap automobile catalyst (SAC) as a catalyst. The optimum reaction conditions (solvent, reaction time, and catalyst amount) were determined. Our results showed that the linoleic acid was reduced to elaidic acid in the sunflower oil. This procedure not only gives high yields but also allows recycling of automobile wastes as a catalyst in organic reactions and is representative of green chemistry.

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