Abstract
Objective A retrospective study, handling the prognostic factors for bile leak and long term survival in 23 patients, with Hilar Cholangiocarcinoma, Bismuth Type III exclusively. Methods Between 2010 and 2017, 23 patients underwent major hepatectomy for Type III Klatskin Tumor at our institution. 11 patients underwent hepatectomy for Type IIIB tumors, 10 patients underwent right hepatectomy for Type IIIA and 2 were omitted for loss of follow-up. Results In 20 patients an R0 resection was achieved. Survival at 1, 3 and 5 years was respectively 78.3%, 61.9% and 38.1%. A BMI > 24 kg/m2 at presentation, was associated with a worse prognosis, at 1, 3 and 5 years, with statistical significance (p<0.05). A Creatinine > 0.74 at presentation, was associated with a decreased 5-year survival, with statistical significance (p<0.05). Conclusion A BMI > 24 kg/m2, a Creatinine > 0.74, are factors of worse prognosis when present in a Type III Klatskin tumor patient. Age, sex, hemoglobin level, tumor size, cusa use, and the correlation of Type IIIB tumors with bile leakage, are all variables that showed borderline significance, and thus warrant further investigations in larger studies, using multicentric data.