Delayed association of acute particulate matter 2.5 air pollution exposure with loss of complexity in cardiac rhythm dynamics: insight from detrended fluctuation analysis

2020 ◽  
Author(s):  
Tsung-Ying Tsai ◽  
Li-Wei Lo ◽  
Shin-Huei Liu ◽  
Wen-Han Cheng ◽  
Yu-Hui Chou ◽  
...  
Keyword(s):  
Air Pollution ◽  
Particulate Matter ◽  
Cardiac Rhythm ◽  
Detrended Fluctuation Analysis ◽  
Fluctuation Analysis ◽  
Air Pollution Exposure ◽  
Particulate Matter 2.5 ◽  
Pollution Exposure ◽  
Detrended Fluctuation

scholarly journals Air pollution and the development of asthma from birth until young adulthood

2020 ◽  
Vol 56 (1) ◽  
pp. 2000147 ◽  
Author(s):  
Ulrike Gehring ◽  
Alet H. Wijga ◽  
Gerard H. Koppelman ◽  
Judith M. Vonk ◽  
Henriette A. Smit ◽  
...  
Keyword(s):  
Air Pollution ◽  
Particulate Matter ◽  
Early Adulthood ◽  
Childhood And Adolescence ◽  
Asthma Incidence ◽  
Mite Allergy ◽  
Increased Risk ◽  
Air Pollution Exposure ◽  
Pollution Exposure ◽  
The Impact

BackgroundAir pollution is associated with asthma development in children and adults, but the impact on asthma development during the transition from adolescence to adulthood is unclear. Adult studies lack historical exposures and consequently cannot assess the relevance of exposure during different periods of life. We assessed the relevance of early-life and more recent air pollution exposure for asthma development from birth until early adulthood.MethodsWe used data of 3687 participants of the prospective Dutch PIAMA (Prevention and Incidence of Asthma and Mite Allergy) birth cohort and linked asthma incidence until age 20 years to estimated concentrations of nitrogen dioxide (NO2), particulate matter with a diameter <2.5 μm (PM2.5), <10 μm (PM10), and 2.5–10 μm, and PM2.5 absorbance (“soot”) at the residential address. We assessed overall and age-specific associations with air pollution exposure with discrete time-hazard models, adjusting for potential confounders.ResultsOverall, we found higher incidence of asthma until the age of 20 years with higher exposure to all pollutants at the birth address (adjusted odds ratio (95% CI) ranging from 1.09 (1.01–1.18) for PM10 to 1.20 (1.10–1.32) for NO2) per interquartile range increase) that were rather persistent with age. Similar associations were observed with more recent exposure defined as exposure at the current home address. In two-pollutant models with particulate matter, associations with NO2 persisted.ConclusionsExposure to air pollution, especially from motorised traffic, early in life may have long-term consequences for asthma development, as it is associated with an increased risk of developing asthma through childhood and adolescence into early adulthood.

scholarly journals Air pollution interventions and respiratory health: a systematic review

2020 ◽  
Vol 24 (2) ◽  
pp. 150-164 ◽  
Author(s):  
S. Saleh ◽  
W. Shepherd ◽  
C. Jewell ◽  
N. L. Lam ◽  
J. Balmes ◽  
...  
Keyword(s):  
Air Pollution ◽  
Particulate Matter ◽  
Respiratory Health ◽  
Grey Literature ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
Potential Health ◽  
Exposure Reduction ◽  
Air Pollution Exposure ◽  
Pollution Exposure

BACKGROUND: Indoor and ambient air pollution exposure is a major risk to respiratory health worldwide, particularly in low- and middle-income countries (LMICs). Interventional trials have mainly focused on alternatives to cooking stoves, with mixed results. Beyond cooking, additional sources of particulate matter also contribute to the burden of air pollution exposure. This review explores evidence from current randomised controlled trials (RCTs) on the clinical effectiveness of interventions to reduce particulate matter in LMICs.METHODS: Twelve databases and the grey literature (e.g., Government reports and policy papers) were searched. Eligible studies were RCTs conducted in LMICs aiming to reduce particulate exposure from any source and reporting on at least one clinical respiratory outcome (respiratory symptoms, lung function or clinical diagnoses). Data from relevant studies were systematically extracted, the risk of bias assessed and narrative synthesis provided.RESULTS: Of the 14 included studies, 12 tested ‘improved' cookstoves, most using biomass, but solar and bioethanol cookers were also included. One trial used solar lamps and another was an integrated intervention incorporating behavioural and environmental components for the treatment and prevention of chronic obstructive pulmonary disease. Of the six studies reporting child pneumonia outcomes, none demonstrated significant benefit in intention-to-treat analysis. Ten studies reported respiratory symptom outcomes with some improvements seen, but self-reporting made these outcomes highly vulnerable to bias. Substantial inter-study clinical and methodological heterogeneity precluded calculation of pooled effect estimates.CONCLUSION: Evidence from the RCTs performed to date suggests that individual household-level interventions for air pollution exposure reduction have limited benefits for respiratory health. More comprehensive approaches to air pollution exposure reduction must be developed so their potential health benefits can be assessed.

scholarly journals Personal-Level Protective Actions Against Particulate Matter Air Pollution Exposure: A Scientific Statement From the American Heart Association

Circulation ◽  
2020 ◽  
Vol 142 (23) ◽  
Author(s):  
Sanjay Rajagopalan ◽  
Michael Brauer ◽  
Aruni Bhatnagar ◽  
Deepak L. Bhatt ◽  
Jeffrey R. Brook ◽  
...  
Keyword(s):  
Air Pollution ◽  
Particulate Matter ◽  
American Heart Association ◽  
American Heart ◽  
Heart Association ◽  
Writing Group ◽  
Air Pollution Exposure ◽  
Scientific Statement ◽  
Personal Level ◽  
Pollution Exposure

Since the publication of the last American Heart Association scientific statement on air pollution and cardiovascular disease in 2010, unequivocal evidence of the causal role of fine particulate matter air pollution (PM 2.5 , or particulate matter ≤2.5 μm in diameter) in cardiovascular disease has emerged. There is a compelling case to provide the public with practical personalized approaches to reduce the health effects of PM 2.5 . Such interventions would be applicable not only to individuals in heavily polluted countries, high-risk or susceptible individuals living in cleaner environments, and microenvironments with higher pollution exposures, but also to those traveling to locations with high levels of PM 2.5 . The overarching motivation for this document is to summarize the current evidence supporting personal-level strategies to prevent the adverse cardiovascular effects of PM 2.5 , guide the use of the most proven/viable approaches, obviate the use of ineffective measures, and avoid unwarranted interventions. The significance of this statement relates not only to the global importance of PM 2.5 , but also to its focus on the most tested interventions and viable approaches directed at particulate matter air pollution. The writing group sought to provide expert consensus opinions on personal-level measures recognizing the current uncertainty and limited evidence base for many interventions. In doing so, the writing group acknowledges that its intent is to assist other agencies charged with protecting public health, without minimizing the personal choice considerations of an individual who may decide to use these interventions in the face of ongoing air pollution exposure.

Respiratory Effects of Particulate Matter Exposure During Short-Term Cycling Among Healthy Adults in Three Chinese Cities

2020 ◽  
Author(s):  
Lejian He ◽  
Laijun Zhao ◽  
Yonghong Liu ◽  
Zhaowen Qiu ◽  
H. Oliver Gao
Keyword(s):  
Air Pollution ◽  
Particulate Matter ◽  
Lung Function ◽  
Fine Particles ◽  
Aerodynamic Diameter ◽  
Short Term ◽  
Respiratory Effects ◽  
Air Pollution Exposure ◽  
Pollution Exposure ◽  
The Impact

Abstract Background: Cycling to work has been promoted as a green commute in many countries because of its reduced congestion relative to that of cars and its reduced environmental impact on air pollution. However, cyclists might be exposed to higher air pollution, causing adverse health effects. Few studies have examined the respiratory effects of traffic-related air pollution exposure during short-term cycling, especially in developing countries with heavy air pollution. The aim of this study was to assess the impact of air pollution exposure on lung function while cycling in traffic. Methods: Twenty-five healthy adults in total cycled on a specified route in each of three Chinese cities during four periods of a day. Lung function measures were collected immediately before and after cycling. Real-time particulate matter (PM) and the particle number count (PNC) for particles with different sizes were measured along each cycling route, while ambient sulfur dioxide (SO2), nitrogen dioxide (NO2), ozone (O3), and carbon monoxide (CO) levels were measured at the nearest stations. Mixed-effect models were used to estimate the impact of short-term air pollution exposure on participants’ lung function measures during cycling. Results: We found that an interquartile increase in particulate matter consisting of fine particles (PM1, aerodynamic diameter £ 1 mm; and PM2.5, aerodynamic diameter £ 2.5 mm) was associated with a significant decrease in forced vital capacity (FVC) (PM1, –5.61%, p = 0.021; PM2.5, –5.57%, p = 0.022). Interquartile increases in the 99th percentile of PNC for fine particles (aerodynamic diameter 0.3–0.4 mm) also had significant negative associations with FVC (0.3 mm, –5.13%, p = 0.041; 0.35 mm, –4.81%, p = 0.045; 0.4 mm, –4.59%, p = 0.035). We also observed significant inverse relationships between ambient CO levels and FVC (–5.78%, p = 0.015).Conclusions: Our results suggest that short-term exposure to fine particles and CO while cycling in traffic contributes to a reduction in FVC of cyclists.

Particulate Matter Air Pollution Exposure And Adult-Onset Asthma And Copd In The Nurses' Health Study

2015 ◽  
Vol 2015 (1) ◽  
pp. 919
Author(s):  
Jared A Fisher ◽  
Robin C. Puett ◽  
Jaime E. Hart ◽  
Carlos A. Camargo ◽  
Raphaelle Varraso ◽  
...  
Keyword(s):  
Air Pollution ◽  
Particulate Matter ◽  
Health Study ◽  
Adult Onset ◽  
Air Pollution Exposure ◽  
Pollution Exposure

scholarly journals Growing evidence links air pollution exposure to risk of Alzheimer’s disease and related dementia

Brain ◽  
2019 ◽  
Vol 143 (1) ◽  
pp. 8-10
Author(s):  
Melinda C Power
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Air Pollution ◽  
Particulate Matter ◽  
Episodic Memory ◽  
Memory Decline ◽  
Air Pollution Exposure ◽  
Pollution Exposure

This scientific commentary refers to ‘Particulate matter and episodic memory decline mediated by early neuroanatomic biomarkers of Alzheimer’s disease’, by Younan et al. (doi: 10.1093/brain/awz348).

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