Serum total sialic acid levels in smokers and users of smokeless tobacco in form of oral powder (Maraş powder)

Maraş powder (MP), a different type of smokeless tobacco (ST) and prepared from a tobacco of speciesNicotiana rusticaLinn, is widely used in Turkey. We aimed to investigate the effects of MP on salivary total sialic acid (TSA) and malondialdehyde (MDA) levels and to compare these parameters in smokers and MP users (MPUs). The salivary TSA and MDA concentrations were significantly higher in the smokers and MPU than those of control subjects and also in MPU than that of smokers. We have also observed that as the number of cigarettes consumed and MP amount increases, TSA and MDA levels increase too. In smokers, MDA values were significantly correlated with the number of cigarettes smoked and the duration of smoking. In MPU, both MDA and TSA levels were significantly correlated with the duration of MP use and the amount of daily consumed MP. We have concluded increased salivary TSA and MDA levels associated in MPU and smokers. Results can help to evaluate harmful effects of these habits. It is important to point out that bigger change in the measured parameters has been observed for MP use. This observation may be an important indication of harmful effects of ST use as MP.

Download Full-text

Salivary Total Sialic Acid Levels Increase in Breast Cancer Patients: A Preliminary Study

Medicinal Chemistry ◽

10.2174/157340611796799230 ◽

2011 ◽

Vol 7 (5) ◽

pp. 443-447 ◽

Cited By ~ 16

Author(s):

Leyla Koc Ozturk ◽

Ebru Emekli-Alturfan ◽

Emel Kasikci ◽

Gokhan Demir ◽

Aysen Yarat

Keyword(s):

Breast Cancer ◽

Sialic Acid ◽

Cancer Patients ◽

Breast Cancer Patients ◽

Total Sialic Acid ◽

Preliminary Study

Download Full-text

Studies on the к-casein complex: II. The isolation of a sialic acid-containing fraction by disrupting the complex at low pH in the presence of sodium chloride

Journal of Dairy Research ◽

10.1017/s0022029900018379 ◽

1965 ◽

Vol 32 (1) ◽

pp. 57-63 ◽

Cited By ~ 9

Author(s):

R. Beeby

Keyword(s):

Sialic Acid ◽

Sodium Chloride ◽

Deae Cellulose ◽

Low Ph ◽

The Other ◽

Trichloracetic Acid ◽

Complex Ii ◽

Total Sialic Acid

SummaryWhen crude к-casein was precipitated at pH 3 in the presence of 0·4m-NaCl the supernatant contained up to 80% of the total sialic acid but no detectable cystine or cysteine. Two fractions were obtained from this supernatant by chromatography on DEAE cellulose; one containing 4–6% sialic acid and the other only onetenth of this amount.Most of the sialic acid of the sialic acid-rich fraction was soluble in 12% trichloracetic acid following treatment with rennin. It is suggested that the glycopeptide released by the action of the enzyme on casein originates from this fraction.

Download Full-text

Effects of Smokeless Tobacco “Maras Powder” Use on Respiratory Functions

The Tohoku Journal of Experimental Medicine ◽

10.1620/tjem.204.173 ◽

2004 ◽

Vol 204 (3) ◽

pp. 173-178 ◽

Cited By ~ 9

Author(s):

Mehmet Akif Buyukbese ◽

Nurhan Koksal ◽

Aytekin Guven ◽

Ali Cetinkaya

Keyword(s):

Smokeless Tobacco ◽

Maras Powder

Download Full-text

The evaluation of serum total sialic acid and lipid-bound sialic acid levels in chronically exposed rats to 7,12-dimethylbenz(a)anthracene and fluoride

10.1063/1.4981754 ◽

2017 ◽

Author(s):

Gokhan Oto ◽

Suat Ekin ◽

Hasan Uyar ◽

Hulya Ozdemir ◽

Damla Yıldız ◽

...

Keyword(s):

Sialic Acid ◽

Total Sialic Acid

Download Full-text

A STUDY OF TOTAL SIALIC ACID AND LIPID BOUND SIALIC ACID LEVELS AND TOTAL SIALIC ACID TO TOTAL PROTEIN RATIO IN CANCER PATIENTS

Journal of Evolution of Medical and Dental Sciences ◽

10.14260/jemds/2017/391 ◽

2017 ◽

Vol 6 (22) ◽

pp. 1778-1783

Author(s):

Sarat Chandan Tummalacharla ◽

Gonella Geetha Meenakshi

Keyword(s):

Sialic Acid ◽

Cancer Patients ◽

Total Protein ◽

Protein Ratio ◽

Total Sialic Acid

Download Full-text

Increased Oxidative Stress Related To Using Smokeless Tobacco Maras Powder

Turkish Thoracic Journal ◽

10.5152/ttd.2011.22 ◽

2011 ◽

Vol 12 (3) ◽

pp. 94-99 ◽

Cited By ~ 3

Author(s):

Elif Kose ◽

Ozlem Yazicioglu Mocin ◽

Hakim Celik ◽

Mehmet Gencer

Keyword(s):

Oxidative Stress ◽

Smokeless Tobacco ◽

Maras Powder

Download Full-text

Serum Total Sialic Acid and Highly Sensitive C-reactive Protein: Prognostic Markers for the Diabetic Nephropathy

Journal of Laboratory Physicians ◽

10.4103/0974-2727.176230 ◽

2016 ◽

Vol 8 (01) ◽

pp. 025-029 ◽

Cited By ~ 6

Author(s):

Vandana Varma ◽

Meena Varma ◽

Amit Varma ◽

Ravindra Kumar ◽

Anuradha Bharosay ◽

...

Keyword(s):

Diabetes Mellitus ◽

Diabetic Nephropathy ◽

Sialic Acid ◽

Multinomial Logistic Regression ◽

C Reactive Protein ◽

Diabetes Mellitus Group ◽

Reactive Protein ◽

Total Sialic Acid ◽

Highly Sensitive ◽

Hs Crp

ABSTRACT Background: This study was undertaken to evaluate and establish the role of total sialic acid (TSA) and highly sensitive C-reactive protein (hs-CRP) in type 2 diabetes mellitus (T2DM) and its correlation with complications such as diabetic nephropathy. Materials and Methods: One hundred fifty-seven patients with T2DM with nephropathy (DN) and 162 patients of T2DM without nephropathy (DM) along with 165 unrelated age and sex-matched healthy controls were included in the study. Serum glucose (fasting and postprandial) levels, renal profile, and lipid profile were done as per standard protocol. Serum TSA test levels and hs-CRP level were evaluated using thiobarbituric acid assay and immunoturbidimetric method respectively. Results: We observed a higher concentration of serum TSA (82.67 ± 6.63 mg/dl) and hs-CRP (3.2 ± 1.44 mg/L) in diabetic nephropathy than the diabetes mellitus group (73.83 ± 6.90 mg/dl and 2.07 ± 1.32 mg/L, respectively). Both TSA and hs-CRP levels were found significantly correlated with fasting and postprandial blood sugar, hemoglobin A1c, and urine microalbumin levels in both DM and DN groups. Multinomial logistic regression analysis showed that both TSA and hs-CRP was independently associated with diabetic nephropathy. Conclusion: High serum TSA and hs-CRP levels may increase the microangiopathic (diabetic nephropathy) complications of T2DM.

Download Full-text