Animal Models in Bariatric Surgery—A Review of the Surgical Techniques and Postsurgical Physiology

2010 ◽  
Vol 20 (9) ◽  
pp. 1293-1305 ◽  
Author(s):  
Raghavendra S. Rao ◽  
Venkatesh Rao ◽  
Subhash Kini
Keyword(s):  
Bariatric Surgery ◽  
Animal Models ◽  
Surgical Techniques

Factors Predictive of Venous Thromboembolism in Bariatric Surgery

2011 ◽  
Vol 77 (10) ◽  
pp. 1403-1406 ◽  
Author(s):  
Hossein Masoomi ◽  
Brian Buchberg ◽  
Kevin M. Reavis ◽  
Steven D. Mills ◽  
Michael Stamos ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Gastric Bypass ◽  
Venous Thromboembolism ◽  
Surgical Techniques ◽  
Significant Risk ◽  
Patient Characteristics ◽  
Morbidly Obese ◽  
Open Gastric Bypass ◽  
Open Operation ◽  
Surgical Options

Venous thromboembolism (VTE) is a significant cause of morbidity and mortality in bariatric surgery. The aim of this study was to evaluate the effect of patient characteristics, payer type, comorbidities, and surgical techniques on development of VTE in bariatric surgery. Using the National Inpatient Sample (NIS) database from 2006 to 2008, clinical data of 304,515 morbidly obese patients who underwent bariatric surgery were examined. Multiple regression analysis was performed to identify factors predictive of VTE. The overall rate of in-hospital VTE was 0.17 per cent, with the highest rate of VTE observed in open gastric bypass (0.45%). The VTE rate was significantly lower in laparoscopic compared with open gastric bypass (0.13% vs 0.45%, respectively, P < 0.01) and in nongastric bypass compared with gastric bypass procedures (0.06% vs 0.21%, respectively, P < 0.01). Alcohol abuse [odds ratio (OR): 8.7], open operation (OR: 2.5), gastric bypass procedures (OR: 2.4), renal failure (OR: 2.3), congestive heart failure (OR: 2.0), male gender (OR: 1.5), and chronic lung disease (OR: 1.4) were associated with a higher rate of VTE. This study identified several significant risk factors for development of VTE in bariatric surgery. To minimize the risk of VTE, surgeons may consider these factors in selection of appropriate prophylaxis and bariatric surgical options.

Revisional Bariatric Surgery

2018 ◽  
Author(s):  
Catherine Frenkel ◽  
Aurora Pryor
Keyword(s):  
Bariatric Surgery ◽  
Weight Loss ◽  
Weight Regain ◽  
Gastric Band ◽  
Surgical Techniques ◽  
Jejunoileal Bypass ◽  
Revisional Bariatric Surgery ◽  
Laparoscopic Gastric Band ◽  
Ensure Patient Safety ◽  
Failed Weight Loss

The annual volume of bariatric surgery is growing, giving rise to an increase in complications requiring complex management, including revision. Bariatric revision procedures are also becoming increasingly necessary for weight-loss recidivism and patients at the extreme of obesity. This chapter outlines clinical management pathways used to address secondary bariatric surgery. It summarizes reasons for, and outcomes with, revision of a laparoscopic gastric band, vertical banded gastroplasty, sleeve gastrectomy, or Roux-en-Y gastric bypass. Surgical techniques used to manage weight regain or failed weight loss after bariatric surgery are also discussed. Finally, surgical solutions for bariatric surgery-induced malnutrition are described, particularly in the setting of biliopancreatic diversion, duodenal switch, or jejunoileal bypass. Overall, the chapter concludes that standardization of revisional procedures can have a significant patient impact, and guidelines must be evidence-based in order to ensure patient safety and success.

scholarly journals Small animal models of heart failure

2019 ◽  
Vol 115 (13) ◽  
pp. 1838-1849 ◽  
Author(s):  
Christian Riehle ◽  
Johann Bauersachs
Keyword(s):  
Heart Failure ◽  
Animal Models ◽  
Surgical Techniques ◽  
Treatment Strategies ◽  
Small Animal ◽  
Therapeutic Strategies ◽  
Genetic Modifications ◽  
Small Animal Models ◽  
New Treatment ◽  
Underlying Mechanisms

Abstract Heart disease is a major cause of death worldwide with increasing prevalence, which urges the development of new therapeutic strategies. Over the last few decades, numerous small animal models have been generated to mimic various pathomechanisms contributing to heart failure (HF). Despite some limitations, these animal models have greatly advanced our understanding of the pathogenesis of the different aetiologies of HF and paved the way to understanding the underlying mechanisms and development of successful treatments. These models utilize surgical techniques, genetic modifications, and pharmacological approaches. The present review discusses the strengths and limitations of commonly used small animal HF models, which continue to provide crucial insight and facilitate the development of new treatment strategies for patients with HF.

Long-Term Food Tolerance After Bariatric Surgery: Comparison of Three Different Surgical Techniques

2017 ◽  
Vol 27 (11) ◽  
pp. 2868-2872 ◽  
Author(s):  
Oscar Cano-Valderrama ◽  
Andrés Sánchez-Pernaute ◽  
Miguel A. Rubio-Herrera ◽  
Inmaculada Domínguez-Serrano ◽  
Antonio J. Torres-García
Keyword(s):  
Bariatric Surgery ◽  
Surgical Techniques ◽  
Food Tolerance

scholarly journals History of surgical treatment of obesity and metabolic disorders

2018 ◽  
Vol 9 (4) ◽  
pp. 87-104
Author(s):  
Dmitrij I. Vasilevsky ◽  
Yuri I. Sedletsky ◽  
Kristina A. Anisimova ◽  
Leysan I. Davletbaeva
Keyword(s):  
Bariatric Surgery ◽  
Surgical Treatment ◽  
Cultural Values ◽  
Medical Science ◽  
Surgical Techniques ◽  
Main Idea ◽  
Surgical Interventions ◽  
Minimally Invasive Surgical ◽  
Negative Side Effects ◽  
Stomach Volume

Surgery of obesity (bariatric surgery) as a separate area of medical science dates back its history from the middle of the previous century. The foundation for its development was based on the ideas of physiology of digestion, the causes and mechanisms of its disturbances that had been formed at that time. An important role was played by achievements in related areas of medicine: anesthesiology, transfusiology. Before that effective antibacterial drugs have already been created. Rich experience in various fields was brought for medicine by the Second World War. The return of society to pre-war cultural values became the impetus for bariatric surgery genesis. For two first decades, the main method of surgical treatment of overweight was shunting operations in the small intestine, aimed at reducing absorption of nutrients (malabsorption techniques). However, a significant number of negative side effects gradually forced to abandon this group of procedures and were the basis for the search for other options in surgical interventions. Since the late 60-es of the 20th century for two decades, methods have been actively developed that limited the flow of nutrients (restrictive approach). The main idea in the development of this group of operations was to reduce the volume of the stomach. At the same time, attempts were made to combine both malabsorptive and restrictive mechanisms in one technique. By the beginning of the 90-es, practically all the available variants of surgical interventions have been proposed and introduced into clinical practice. At the same time, minimally invasive surgical technologies began to be actively introduced into this area of medicine. By the beginning of the 21st century almost all surgical techniques have been adapted to endovideo- (laparoscopic-) surgery. Over the past decade, intraluminal (endoscopic) methods for reducing stomach volume and reducing nutrient absorption have been developed.

scholarly journals BARIATRIC SURGERY IN BRAZILIAN PUBLIC HEALTH SYSTEM: THE GOOD, THE BAD AND THE UGLY, OR A LONG WAY TO GO. YELLOW SIGN!

2019 ◽  
Vol 32 (4) ◽  
Author(s):  
Antoninho José TONATTO-FILHO ◽  
Felipe Melloto GALLOTTI ◽  
Marcio Fernandes CHEDID ◽  
Tomaz de Jesus Maria GREZZANA-FILHO ◽  
Ana Maria Stapasolla Vargas GARCIA
Keyword(s):  
Public Health ◽  
Bariatric Surgery ◽  
Health System ◽  
Public Health System ◽  
Descriptive Analysis ◽  
Age Groups ◽  
Surgical Techniques ◽  
Current Status ◽  
The Public ◽  
Health Registry

ABSTRACT Background: In Brazil, there has been a significant increase in obesity rates in all age groups. Data from 2017 show that obesity affects 19% of the population. Due to the magnitude of the problem, public health policies have aimed to prevent complications related to obesity by increasing the offerfor bariatric surgeries. Aim: To analyze the current status of bariatric surgery performed in the Brazilian public health system, including data from macroregions and also the effect of digestive surgery training on the number of procedures. Methods: The database of the public health registry (DATASUS) was assessedbetween 2008 and 2018 for descriptive analysis of data and evaluation of the selected parameters. The main surgical techniques, comorbidities, mortality and the costs profile of the system were evaluated. Results: There was a 339% increase in the number of bariatric surgeries in the period evaluated. Gastric bypass was performed in 94% of cases whereas sleeve in 2.4%. Other techniques were used in 3.6%. There were discrepancies in the number of surgeries performed in different regions of the country. Conclusion: There was a considerable advance in the number of bariatric surgeries performed by the public health system between 2008 and 2018. However, there is a need to increase the offer of this service and alsospecialized training, as well as a correction in the distribution of these procedures in the national territory to achieve integrality among its users.

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